Isotretinoin is active in the initial management of acute pro-myelocytic leukemia [0.03%]
异维甲酸在急性早幼粒细胞白血病初始治疗中发挥重要作用
Husain Y Alkhaldy,Ali M Assiri,Sohaila Fatima et al.
Husain Y Alkhaldy et al.
Pro-myelocytic acute leukemia (APL) is characterized by the proliferation of cells blocked at promyelocytic stage and ATRA is the choice of initial treatment because of the APL sensitivity to this compound. In this case study we report a 28...
Targeted therapy for medullary and extramedullary relapse of FLT3-ITD acute myeloid leukemia following allogeneic hematopoietic stem cell transplantation [0.03%]
异基因造血干细胞移植后FLT3-ITD急性髓系白血病髓内和髓外复发的靶向治疗
Takahiro Kumode,Shinya Rai,Hirokazu Tanaka et al.
Takahiro Kumode et al.
We report a case with extramedullary tumors affecting the supraclavicular region that presented as a relapse of acute myeloid leukemia (AML) with FLT3-ITD mutation after allogeneic hematopoietic stem cell transplantation (allo-HSCT). Treatm...
Screening for an underlying myeloproliferative neoplasm in patients with thrombocytosis post-induction chemotherapy for acute myeloid leukemia [0.03%]
急性髓系白血病诱导化疗后血小板增多患者潜在骨髓增生性肿瘤的筛查
Stephen E Langabeer
Stephen E Langabeer
Near tetrapoloid karyotype with translocation t(11;14) in a Moroccan patient with amyloid light-chain amyloidosis and multiple myeloma [0.03%]
伴有染色体易位t(11;14)的近四倍体核型出现在一名摩洛哥患者中，该患同时患有轻链淀粉样变性和多发性骨髓瘤
Hasna Hamdaoui,Abdelhafid Natiq,Oumaima Benlarroubia et al.
Hasna Hamdaoui et al.
Cytogenetic and iFISH plays a major part in the diagnosis of the MM and have an important prognostic significance. 10-15% of patients with amyloidosis will also have multiple myeloma (MM). Few studies have addressed the clinical and cytogen...
Y S Jethava,Rafael Fonseca,Ola Landgren
Y S Jethava
At the end of 2019, a novel coronavirus was identified as the cause of pneumonia cases in Wuhan, a city in the Hubei Province of China. On January 30, 2020, the World Health Organization (WHO) declared the COVID-19 outbreak a public health ...
Immune checkpoints bone marrow expression as the predictor of clinical outcome in myelodysplastic syndrome [0.03%]
免疫检查点骨髓表达作为预测骨髓增生异常综合征预后的标志
Nikolai Tcvetkov,Artem Gusak,Elena Morozova et al.
Nikolai Tcvetkov et al.
Aims: In our single-center retrospective study we evaluated whether level of different checkpoint molecules in bone marrow biopsies at diagnosis affect the clinical course of patients with myelodysplastic syndrome (MDS). ...
A rare case of acute myeloid leukemia with t(12;19)(q13;q13) [0.03%]
涉及12号和19号染色体易位(t(12;19)(q13;q13))的急性髓系白血病罕见病例报告
Alain Chebly,Fady Gh Haddad,Josiane Bassil et al.
Alain Chebly et al.
Acute myeloid leukemia (AML) is characterized by chromosomal abnormalities affecting both prognosis and course of treatment. While most AML patients have well described chromosomal aberrations, around 10% present with rare chromosomal abnor...
BCR-ABL tyrosine kinase inhibitor (TKI)-induced nephropathy: An under-recognized phenomenon [0.03%]
BCR-ABL酪氨酸激酶抑制剂(TKI)诱导的肾损害：一种被忽视的现象
Michele Stanchina,Zoe McKinnell,Jae H Park et al.
Michele Stanchina et al.
Nicolette T Morris,Mihaela B Taylor,Melkon Hacobian et al.
Nicolette T Morris et al.
An association between tyrosine-kinase inhibitor therapy for chronic myeloid leukemia and vascular adverse events including peripheral arterial disease, coronary artery disease, and pulmonary hypertension has been described. We present a pa...
First case of near haploid philadelphia negative B-Cell acute lymphoblastic leukaemia relapsing as acute myeloid leukemia following allogeneic hematopoietic stem cell transplantation [0.03%]
首例费城染色体阴性近单倍体B细胞急性淋巴细胞白血病allo-HSCT后复发为急性髓系白血病
Claire Horgan,Charalampos Kartsios,Emmanouil Nikolousis et al.
Claire Horgan et al.
Herein we present a female patient aged 61 with Philadelphia negative acute lymphoblastic leukaemia demonstrating near haploid karyotype and abnormal TP53 expression at diagnosis, who relapsed with lineage switch as Acute Monocytic Leukemia...