COVID-19 in patients with acute leukemia: Two cases with different outcomes [0.03%]
急性白血病患者感染新冠肺炎病毒感染：两例不同结局的病例报告
Venkat Rajasurya,Kathleen Elliott,James Dugan et al.
Venkat Rajasurya et al.
Use of Tocilizumab in Management of Post-Operative Myelomonocytic Leukemoid Reaction [0.03%]
托珠单抗治疗术后髓单核细胞类白血病反应病例报告
Megan Melody,Emily Butts,David Menke et al.
Megan Melody et al.
Interleukin 6 receptor (IL6R) inhibitor, tocilizumab, has been effectively used in the treatment of cytokine release syndrome in patients receiving chimeric antigen receptor T-cell therapy. Here we present a patient with chronic myelomonocy...
Plerixafor on-demand in association with low-dose cyclophosphamide and G-CSF in the mobilization of patients with multiple myeloma: High effectiveness, low toxicity, and affordable cost [0.03%]
低剂量环磷酰胺联合普乐沙福和G-CSF在多发性骨髓瘤患者动员中的效果、安全性及经济性分析
Giuseppe Milone,Concetta Conticello,Salvatore Leotta et al.
Giuseppe Milone et al.
In CD34+ cells mobilization of patients with multiple myeloma (MM), the use of Cyclophosphamide (CTX) at a dose of 2 g/m2 has low efficacy although also lower toxicity. The suboptimal mobilizing effect of low-dose CTX, however, may be overc...
Efficacy of ruxolitinib in a patient with myelodysplastic/myeloproliferative neoplasm unclassifiable and co-mutated JAK2, SF3B1 and TP53 [0.03%]
利妥昔替尼治疗共突变JAK2、SF3B1和TP53的无法分类的骨髓增生异常/骨髓增殖性肿瘤患者的疗效
Qian Wang,Hai-Ping Dai,Dan-Dan Liu et al.
Qian Wang et al.
Myelodysplastic/myeloproliferative neoplasm, unclassifiable (MDS/MPN-U) is a rare but heterogeneous subtype of MDS/MPN, with no specific genetic alterations and standard treatments. ASXL1, SRSF2, TET2, JAK2 and NRAS are commonly mutated in ...
Focal blast crisis in concomitant myelodysplastic syndrome and chronic myelogenous leukemia [0.03%]
伴发骨髓增生异常综合征的慢性粒细胞白血病急变期的特点
Leo Reap,Lyle Goldman
Leo Reap
Leukemic transformation of myelodysplastic syndrome (MDS) or chronic myelogenous leukemia (CML) is a well-established phenomenon. However, co-occurrence of MDS and CML is a rare phenomenon, with few reports to date. Though blast crisis typi...
Myasthenia Gravis and Large Granular Lymphocytic Leukemia: a rare association [0.03%]
重症肌无力和大颗粒淋巴细胞白血病：一种罕见的联合病症
Yumeng Zhang,Christa Varnadoe,Ankita Tandon et al.
Yumeng Zhang et al.
Myasthenia gravis (MG) is an autoimmune neuromuscular junction disorder sometimes observed in hematologic malignancies as a paraneoplastic syndrome. T-cell Large Granular Lymphocytic Leukemia (T-LGLL) is a rare lymphoproliferative clonal fr...
Vincristine and prednisone regulates cellular and exosomal miR-181a expression differently within the first time diagnosed and the relapsed leukemia B cells [0.03%]
长春新碱和强的松调节初诊和复发B淋巴细胞白血病中的细胞和外泌体miR-181a表达不同
Shabirul Haque,Sarah R Vaiselbuh
Shabirul Haque
We explored the effect of vincristine and prednisone on cellular and exosomal miR-181a expression in first time diagnosed leukemia and relapsed leukemia. Vincristine and prednisone induced apoptosis/pro-apoptotic genes in first time diagnos...
Even mild hemolysis in paroxysmal nocturnal hemoglobinuria could severely compromise the quality of life due to long-term sustained intolerant fatigue [0.03%]
阵发性睡眠性血红蛋白尿即使出现轻微溶血,由于长期耐受性疲劳，也可能严重损害生活质量
Kazuya Sakai
Kazuya Sakai
Fatigue is one of the most common symptoms associated with paroxysmal nocturnal hemoglobinuria (PNH), a rare acquired disorder of hematopoietic stem cells. While it directly impairs lifestyle leading to poor quality of life (QOL), it is not...
A case report and case review: Chronic myeloid leukemia (CML) blast phase with myelomastocytic differentiation [0.03%]
病例报告及文献回顾：慢粒急变期伴髓-嗜酸细胞分化一例报道
Jinming Song,Kenian Liu,Javier Pinilla-Ibarz et al.
Jinming Song et al.
We presented a patient with CML who progressed to unclassical blast phase after Tyrosine Kinase Inhibitors (TKIs) therapy. The patient presented with 2 populations of blasts: one with no cytoplasmic granules and was CD117 weak+/tryptase-/CD...
Primary adrenal extranodal NK/T-cell lymphoma: A case report and literature review [0.03%]
原发性肾上腺 extravascular NK/T细胞淋巴瘤：病例报告及文献回顾
Satoshi Ichikawa,Kei Saito,Noriko Fukuhara et al.
Satoshi Ichikawa et al.
A 37-year-old man was admitted to our department following the detection of bulky tumors in his bilateral adrenal glands. A biopsy resulted in the diagnosis of extranodal NK/T cell lymphoma, nasal type (ENKL). After debulking by chemotherap...