Circulating miRNAs can serve as potential diagnostic biomarkers in chronic myelogenous leukemia patients [0.03%]
循环miRNA可以作为慢性粒细胞白血病患者的潜在诊断生物标志物
Farid Keramati,Arefeh Jafarian,Adele Soltani et al.
Farid Keramati et al.
Introduction: Chronic Myelogenous Leukemia (CML) is a myeloproliferative disorder described as a malignant blood disorder by accounts for 15-20% of all adult leukemia. MicroRNAs (miRNAs) play an important role in post-tra...
Oral etoposide combined with oral arsenic plus retinoic acid for two cases with newly diagnosed high-risk acute promyelocytic leukemia during COVID19 pandemic [0.03%]
依托泊苷联合口服砷剂及维甲酸治疗2例新冠肺炎疫情期间高危全新诊急性早幼粒细胞白血病患者报告
Sheng-Ye Lu,Li Wen-Jing,Rui Lou et al.
Sheng-Ye Lu et al.
Acute promyelocytic leukemia (APL) is a highly curable hematology malignancy. The major factor influence prognosis of APL is early deaths (ED) during the course of induction therapy, especially in high-risk APL. Therefore, effective reducti...
Anti-CD19 CAR T-cell therapy remission despite prior anti-CD19 antibody Tafasitamab in relapsed/refractory DLBCL [0.03%]
来那度胺难治的弥漫大B细胞淋巴瘤(DLBCL)患者接受Tafasitamab治疗后复发,使用抗CD19 CAR-T产品回输获得持久缓解病例报告
Nadeem Tabbara,Daria Gaut,Caspian Oliai et al.
Nadeem Tabbara et al.
Tafasitamab (MOR208) is an Fc-enhanced, humanized, monoclonal antibody that targets CD19. The L-MIND (NCT02399085) trial, an open-label, single-arm, phase II study of Tafasitamab (TAFA) plus lenalidomide (LEN), reported progression-free sur...
Influence of HLA-DPB1 mismatches on outcome after allogeneic hematopoietic stem cell transplantation [0.03%]
HLA-DPB1不匹配对allo-HSCT预后的的影响
Mireille Hunziker,Jakob Passweg,Michael Medinger
Mireille Hunziker
Potent efficacy of chlorpromazine in acute myeloid leukemia harboring KIT-D816V mutation [0.03%]
氯丙嗪对KIT-D816V突变阳性急性髓系白血病具有显著疗效
Shinya Rai,Hirokazu Tanaka,J Luis Espinoza et al.
Shinya Rai et al.
Acute myeloid leukemia (AML) is a heterogeneous disease often associated with poor prognosis. We previously showed that the localization of KIT-D816V at endolysosomes is critical to activate aberrant Akt signaling and Chlorpromazine (CPZ) p...
Distal chromosome 1q aberrations and initial response to ibrutinib in central nervous system relapsed mantle cell lymphoma [0.03%]
染色体1q远端异常与中枢神经系统复发套细胞淋巴瘤患者伊布替尼初始治疗反应的关系研究
Marcus Høy Hansen,Karen Juul-Jensen,Oriane Cédile et al.
Marcus Høy Hansen et al.
Relapse involving the central nervous system (CNS) is an infrequent event in the progression of mantle cell lymphoma (MCL) with an incidence of approximately four percent. We report four cases of MCL with CNS relapse. In three of the four p...
A rare case of B cell lymphoblastic leukemia with inv(7)(p15q34) with review of literature [0.03%]
染色体易位inv(7)(p15q34)伴有的罕见B淋巴母细胞急性白血病病例报告及文献复习
Bernhisel Andrew,Orazi Attilio,Guar Sumit et al.
Bernhisel Andrew et al.
The inv(7)(p15q34) chromosomal abnormality which juxtaposes part of the HOXA gene cluster on 7p15 to the TCRβ locus on 7q34, has been described in a subset of cases of T-cell lymphoblastic leukemia, but its presence in cases of B-cell lymp...
Hyperleukocytosis during clozapine treatment: A rare presentation of B-cell Acute lymphoblastic leukemia [0.03%]
氯氮平治疗期间的高白细胞增多症:B细胞急性淋巴细胞白血病的罕见表现形式
Neslyne B Augustin,Michael Maroules
Neslyne B Augustin
Clozapine has been widely used as an antipsychotic drug for the treatment of refractory schizophrenia. Unfortunately, a wide range of blood dyscrasias have been reported as adverse effects of this drug. Agranulocytosis has gotten the most c...
Lebanese Real-World Experience in Treating Multiple Myeloma: A Multicenter Retrospective Study [0.03%]
一项多中心回顾性研究:黎巴嫩真实世界条件下多发性骨髓瘤的治疗经验
Fadi Nasr,Ahmad Al Ghoche,Saada Diab et al.
Fadi Nasr et al.
Objective: The present retrospective multicenter study aims at documenting characteristics of multiple myeloma (MM) patients and the effect of autologous stem cell transplant (ASCT) on survival. ...
Acute myeloid leukemia with hepatic infiltration presenting as obstructive jaundice [0.03%]
以阻塞性黄疸表现为肝浸润的急性髓系白血病
Landis R Walsh,Chaofan Yuan,James T Boothe et al.
Landis R Walsh et al.
We present the case of a 55-year-old woman who presented with laboratory studies concerning for acute myeloid leukemia (AML) as well as obstructive cholestasis. In similar previously reported cases, concerns of chemotherapy toxicity exacerb...