Gilteritinib monotherapy as a transplant bridging option for high risk FLT3-mutated AML with t(6;9)(p23;q34.1);DEK-NUP214 in morphological but not cytogenetic or molecular remission following standard induction chemotherapy [0.03%]
吉瑞替尼单药治疗标准诱导化疗后形态学缓解但细胞遗传学和分子标志未缓解的高危FLT3突变型伴t(6;9)(p23;q34.1);DEK-NUP214不良染色体类型的急性髓系白血病以进行移植的有效性研究
James W Day,Thomas A Fox,Rajeev Gupta et al.
James W Day et al.
We report a case of FLT3-mutated AML with t(6;9) in which induction chemotherapy with DA and midostaurin failed to achieve complete cytogenetic or molecular remission. Due to the COVID-19 pandemic and co-existing cellulitis, monotherapy wit...
Case of Pulmonary Extramedullary Hematopoiesis Responding to Ruxolitinib [0.03%]
一例对鲁索利替尼有效的肺外造血病例报告
Ayumi Fujimoto,Shunichi Hamaguchi,Ritsuro Suzuki
Ayumi Fujimoto
We report a case of 43-year-old woman diagnosed with essential thrombocythemia in 1992. She was diagnosed with secondary myelofibrosis in 2011. Later, she suffered mild dyspnea, which gradually worsened. She was admitted to our hospital to ...
B/T mixed phenotype acute leukemia with high hyperdiploidy and lineage switch to B-cell acute leukemia [0.03%]
高超二倍体B/T双表型急性白血病向B细胞急淋转换1例报告
Hanaa Skhoun,Mohammed Khattab,Zahra Takki Chebihi et al.
Hanaa Skhoun et al.
Acute leukemias are often of myeloid or lymphoid origin. However, some acute leukemias revealed an undefined differentiation into a single lineage. Mixed phenotype acute leukemia (MPAL) is an uncommon diagnosis were blasts can share B/T/mye...
Satoshi Ichikawa,Noriko Fukuhara,Ko Hashimoto et al.
Satoshi Ichikawa et al.
A 52-year-old man with rapidly progressive paraplegia was presented to us with paravertebral tumors. Laminectomy with tumor resection was performed, and pathological analysis of the tumor revealed compact proliferation of anaplastic plasmac...
Novel biologic therapies in relapsed or refractory diffuse large B cell lymphoma: CAR-T is not the only answer [0.03%]
复发或难治性弥漫大B细胞淋巴瘤的新型生物治疗手段：CAR-T并非唯一选择
Jérôme Paillassa,Firas Safa
Jérôme Paillassa
Patients with diffuse large B-cell lymphoma who have refractory or relapsed disease following first line treatment have a poor prognosis when treated with conventional therapies. Significant efforts have been made in recent years to bring a...
Acute myeloid leukemia with RAM immunophenotype presenting with extensive mesenteric and retroperitoneal lymphadenopathy: A case report and review of the literature [0.03%]
以肠系膜及腹膜后广泛淋巴结肿大为表现的RAM型急性髓系白血病1例并文献复习
N Wick,I Hitto,D Welder et al.
N Wick et al.
Acute myeloid leukemia (AML) with RAM immunophenotype is a rare recently described AML subtype. It is defined by blasts with strong expression of CD56 and weak to absent expression of CD45, HLA-DR....., and CD38 and characterized by signifi...
Bladder Myeloid Sarcoma with TP53 mutated Myelodysplastic Syndrome/Myeloproliferative Neoplasm Overlap syndrome: Response to Decitabine-Venetoclax regimen [0.03%]
TP53突变的骨髓增生性肿瘤/myelodysplastic综合征重叠综合征伴发膀胱粒细胞性肉瘤对地西他滨-维奈克拉方案的反应
Nikeeta Mandhan,Farah Yassine,Ke Li et al.
Nikeeta Mandhan et al.
Myeloid sarcoma (MS) is a rare extramedullary blast proliferation of immature cells of myeloid origin. It is commonly associated with acute myeloid leukemia (AML), myelodysplastic syndrome (MDS), or myeloproliferative neoplasm (MPN), and ma...
Post-operative hyperleukocytosis and leukostasis as the initial presentation of chronic myelomonocytic leukemia: A case report and review of literature [0.03%]
慢性粒单细胞白血病术后发生高白细胞计数和白细胞淤滞的病例报道及文献复习
Sumit Gaur,Alexander Philipovskiy,Attilio Orazi
Sumit Gaur
Leukemoid reactions following surgery are commonly caused by infections or tissue injury. Management is directed towards underlying condition and cytoreduction is not indicated. Chronic myelo-monocytic leukemia (CMML) is a clonal hematologi...
Outcomes of patients with double/triple expressor diffuse large B-cell lymphoma (DLBCL) treated with R-DA-EPOCH/R-CHOP: A single-center experience [0.03%]
R-DA-EPOCH-R-CHOP方案治疗双表达和三表达弥漫大B细胞淋巴瘤患者的疗效分析：单中心经验性研究
Kanta Devi,Muhammad Usman Shaikh,Natasha Bahadur Ali et al.
Kanta Devi et al.
In Pakistan 76.4% of all NHLs to be diagnosed as DLBCLs. The survival of R-CHOP is better compared to the DA-REPOCH treatment regimen. A prospective follow-up study was conducted with 113 patients to study the outcomes of treatment. Multiva...
Bilateral auricular lymphoplasmacytic lymphoma: barely mere coincidence [0.03%]
双侧耳廓淋巴浆细胞淋巴瘤：仅仅是巧合吗？
Leonid L Yavorkovsky,Zuoqin Tang,Anita Tayin Chen Lee
Leonid L Yavorkovsky
We describe the first case of LPL simultaneously involving both auricles. Affected ears were the first manifestation of the disease that led to the diagnosis. The lack of appreciable systemic disease allowed sparing the patient from immunoc...