Incidental discovery of acquired factor X deficiency in a patient with multiple myeloma [0.03%]
偶发发现一例浆细胞瘤合并获得性因子X减少症
Yousra Sbibih,Mohammed Bensalah,Abderrazak Saddari et al.
Yousra Sbibih et al.
Factor X deficiency is a very rare coagulopathy caused by a constitutional or acquired deficiency of factor X, or by the presence of a circulating anticoagulant in the blood. Factor X deficiency has already been described in patients with A...
Evaluating the effectiveness of reduced-intensity conditioning regimens in acute myeloid leukemia patients after hematopoietic stem cell transplantation in Vietnam [0.03%]
评估造血干细胞移植后越南急性髓系白血病患者减量化疗方案的有效性
Man Van Huynh,Huu Than Huynh,Thu Hanh Nguyen et al.
Man Van Huynh et al.
Objective: Hematopoietic stem cell transplantation (HSCT) is an effective treatment for acute myeloid leukemia (AML) patients, leveraging cytotoxic conditioning regimens and graft-versus-leukemia effects. Reduced-intensit...
The role of RAS mutations in leukemia progression, differentiation, and drug resistance [0.03%]
RAS突变在白血病进展、分化和耐药中的作用
Congfa Jiang,Hangxuan Wang,Jiaxin Zhao et al.
Congfa Jiang et al.
Mutations in the RAS gene family (NRAS, KRAS) are critical drivers of late-stage acute myeloid leukemia (AML) progression. They are frequently detected in relapsed/refractory AML and AML transformed from myelodysplastic syndrome (MDS). Occu...
JAK2 V617F mutations and thrombosis in BCR-ABL1 negative myeloproliferative neoplasms: clinical profile and hematologic insights [0.03%]
jak2V617F突变在BCR-ABL1阴性骨髓增生异常/增殖性肿瘤中的血栓形成：临床特征和血液学意义
Anna Mira Lubis,Muhammad Orri Baskoro,Gabriella Anindyah et al.
Anna Mira Lubis et al.
Background: The interplay between JAK2 mutation, thrombosis, and the baseline clinical and hematologic profile of MPN remains poorly understood. This study aims to provide insight on the relationship between the clinical ...
Multidisciplinary approaches to coexisting Glanzmann thrombasthenia and juvenile polyposis syndrome [0.03%]
Glanzmann 血小板病伴幼年性息肉症的多学科诊治体会
Sondus Alsharidah,Eman Almatter,Hana&#x; Nofal et al.
Sondus Alsharidah et al.
Glanzmann thrombasthenia (GT) is a rare autosomal recessive bleeding disorder from defects in the αIIbβ3 integrin receptor, impairing platelet aggregation and often overlooked due to normal platelet counts. Juvenile polyposis syndrome (JP...
Gilteritinib-associated hand-foot syndrome: a novel dermatologic reaction in refractory FLT3 Acute myeloid leukemia [0.03%]
吉瑞替尼相关的手足综合征：难治性FLT3急性髓系白血病的一种新型皮肤反应
Jack T Seki,Jad Sibai,Maria Agustina Perusini et al.
Jack T Seki et al.
Objective: Second generation tyrosine kinase inhibitors (TKIs) such as gilteritinib, characterized by minimal EGFR and absent VEGFR inhibition, are in theory associated with low dermatologic toxicity. This case report bri...
FLT3 inhibitor and venetoclax therapy in elderly patients with relapsed/refractory FLT3-ITD+ AML: A report of three cases [0.03%]
用于治疗复发/难治性FLT3-ITD+AML老年患者的FLT3抑制剂和venetoclax疗法：三例报告
Daisuke Ikeda,Satoshi Uchiyama,Yong-Mei Guo et al.
Daisuke Ikeda et al.
This case report examines three patients with relapsed/refractory FLT3-ITD+ acute myeloid leukemia (AML) treated with FLT3 inhibitors (FLT3i) and venetoclax (VEN). While the combination therapy showed promising antileukemic activity, all pa...
A case report of multifocal gastrointestinal myeloid sarcoma without leukemic involvement: an unusual presentation posing a diagnostic challenge [0.03%]
一例无白血病侵犯的多灶性胃肠粒细胞肉瘤病例报告：一种罕见的具有诊断挑战性的表现形式
Engy S Alhariry,Abdulkarim Hasan,Nageh R Abd-Elhameed et al.
Engy S Alhariry et al.
Myeloid sarcoma is a rare hematologic malignancy defined by the extramedullary proliferation of myeloid blasts. It may occur without concurrent acute myeloid leukemia, creating a significant diagnostic challenge, particularly when it involv...
Encouraging response rates and high mobilization success with brentuximab vedotin plus GDP in adult relapsed/refractory classical Hodgkin lymphoma: A real-world study [0.03%]
brentuximab Vedotin联合吉西他滨/多柔比星/泼尼松治疗成人复发/难治性经典型霍奇金淋巴瘤的高效性和安全性：一项真实世界研究
Sinem Namdaroğlu,Hikmetullah Batgi,Merve Kakcı et al.
Sinem Namdaroğlu et al.
Background: Relapsed or refractory classical Hodgkin lymphoma (R/R cHL) remains challenging, and achieving metabolic complete response prior to autologous stem cell transplantation (ASCT) is important. GDP is a generally ...
Shiqiang Qu,Peihong Zhang,Zefeng Xu et al.
Shiqiang Qu et al.
We report a case of a 25-year-old male with recurrent oral ulcers, upper respiratory tract infections, and an 8-year history of chronic neutropenia. Previously diagnosed with Behçet's disease, the patient had undergone comprehensive hemato...