Severe SARS-CoV-2 and subsequent fungal infections after CAR T-cell therapy for relapsed/refractory multiple myeloma: a challenging and happy ending fight [0.03%]
CAR-T细胞治疗后复发/难治性多发性骨髓瘤患者严重SARS-CoV-2感染及继发真菌感染:充满挑战的战斗,但最终获得胜利
Claudia Ielo,Francesca Fazio,Serena Rocchi et al.
Claudia Ielo et al.
Chimeric antigen receptor (CAR) T-cells have unveiled a promising therapeutic horizon for relapsed/refractory multiple myeloma (R/R MM). Nevertheless, immune impairment induced by cellular therapies, previous treatments and MM itself could ...
Impact of cytogenetic abnormalities in symptomatic multiple myeloma; a Japanese real-world analysis from Kansai Myeloma Forum [0.03%]
染色体异常在症状性多发性骨髓瘤中的影响:来自关西骨髓瘤论坛的日本真实世界分析
Aya Nakaya,Hirohiko Shibayama,Nobuhiko Uoshima et al.
Aya Nakaya et al.
To evaluate the specific prognostic value of CAs, we conducted an analysis of 923 symptomatic multiple myeloma patients. Among this cohort, 480 patients had complete data set of high-risk CAs by interphase fluorescent in situ hybridization ...
Testicular involvement in mantle cell lymphoma: An analysis of 16 patients [0.03%]
套细胞淋巴瘤睾丸受累的临床分析——16例报告
Samer Alkhalili,Dharmini Manogna,Hana Safah et al.
Samer Alkhalili et al.
Mantle cell lymphoma (MCL) with testicular involvement is a rare presentation and only a few cases have been described in the literature. We present a case of MCL with testicular involvement and the first analysis of all previously reported...
Cytogenetic abnormalities correlate with clinico-biological characteristics in 30 Moroccan multiple myeloma patients [0.03%]
细胞遗传学异常与30例摩洛哥多发性骨髓瘤患者的临床生物学特征相关
Hasna Hamdaoui,Badreddine Nouadi,Oumaima Benlarroubia et al.
Hasna Hamdaoui et al.
Background: The nonrandom recurrence of chromosomal abnormalities in multiple myeloma (MM) raises the possibility that they play a role in the pathophysiology and development of the disease. Fluorescence in situ hybridiza...
The use of cell free DNA (cfDNA) for mutational screening of multiple myeloma [0.03%]
利用细胞游离DNA检测多发性骨髓瘤基因突变筛查的方法
A-M Joëlle Marivel,Yafeng Ma,Therese M Becker et al.
A-M Joëlle Marivel et al.
Multiple myeloma (MM) is an incurable haematological malignancy which relies heavily on bone marrow biopsies for disease monitoring and prediction of treatment response. In recent years, liquid biopsy derived cell-free DNA (cfDNA) has emerg...
Leukemic infiltration of the optic nerve in chronic lymphocytic leukemia: A case report and review of literature [0.03%]
慢性淋巴细胞白血病视神经浸润1例报告及文献复习
Louisa Liu,Sana Hadyah,Annie Park et al.
Louisa Liu et al.
Ophthalmic and neurologic involvement are rare complications of CLL, with few cases reported in the literature. We report a case of CLL with leukemic infiltration of the optic nerve and review of literature focusing on management and outcom...
Allogeneic stem cell transplant for multiple myeloma & myelofibrosis with split-dose busulfan, fludarabine & cyclophosphamide [0.03%]
用于多发性骨髓瘤及原发性骨纤的allo移植应用分剂量_busulfan_fludarabine_和环磷酰胺预处理方案
Andrew D Trunk,Sagar S Patel,Josef T Prchal et al.
Andrew D Trunk et al.
Allogeneic stem cell transplant can have high morbidity and mortality in patients with myelofibrosis (MF) and multiple myeloma (MM). This phase 2 study used a novel myeloablative regimen of split-dose busulfan, fludarabine, and then post-tr...
Isochromosome 7p, i(7)(p10): A rare AML, myelodysplasia-related entity [0.03%]
7号染色体短臂异染色体(i(7)(p10)):一种罕见的与骨髓增生异常相关的急性髓系白血病实体
Reza Nejati,Ryan Neumann-Domer,Zemin Liu et al.
Reza Nejati et al.
We describe genomic findings in an AML case with isochromosome 7p, i(7)(p10), in which SNP array analysis uncovered an additional 7.07-Mb 20q deletion not detected by karyotyping. Several AML cases with i(7)(p10) as an isolated cytogenetic ...
Waldenstrom's macroglobulinemia-like B cell lymphoma with MYD88 L265P mutation and t(14;18)(q32;q21) involving IGH - MALT1 [0.03%]
带有MYD88 L265P突变和t(14;18)(q32;q21)涉及IGH-MALT1的华氏巨球蛋白血症样B细胞淋巴瘤
Rie Furuta,Hiro Tatetsu,Jun-Ichirou Yasunaga et al.
Rie Furuta et al.
A 65-year-old woman was referred to the hospital for further investigation of weight loss, hyperproteinemia, and anemia. Serum immunofixation electrophoresis revealed IgM-κ M protein. Bone marrow examination revealed an increase in the num...