A tertiary care centre experience with Elranatamab: A report of three cases [0.03%]
Elranatamab的三级护理中心经验报告：三例报道
Disha Kakkar,Aakanksha Singh,Reshmi Harikumar Pillai et al.
Disha Kakkar et al.
Introduction: The introduction of proteasome inhibitors, immunomodulatory drugs, and monoclonal antibodies has changed the treatment paradigm of multiple myeloma. With the advent of these new therapeutic options, life exp...
Acute myeloid leukemia with a novel AKAP9::PDGFRA fusion transformed from essential thrombocythemia: A case report and mini review [0.03%]
由原发性血小板增多症转化而成的带有新型AKAP9::PDGFRA融合急性髓系白血病1例及文献复习
Yavuz Sahin,Jianming Pei,Don A Baldwin et al.
Yavuz Sahin et al.
Acute myeloid leukemia (AML) is a heterogeneous hematological malignancy associated with various combinations of gene mutations, epigenetic abnormalities, and chromosome rearrangement-related gene fusions. Despite the significant degree of ...
Central nervous system relapse after combination therapy including polatuzumab vedotin in patients with diffuse large B-cell lymphoma [0.03%]
达罗妥尤单抗维多汀联合治疗后弥漫性大B细胞淋巴瘤患者的中枢神经系统复发
Yoshikazu Hori,Hiroki Hosoi,Toshiki Mushino et al.
Yoshikazu Hori et al.
Preventing central nervous system (CNS) relapse is a major challenge in the treatment of diffuse large B-cell lymphoma (DLBCL). However, no previous studies have examined the efficacy of polatuzumab vedotin (PV)-containing regimens in preve...
Sawyer J Bawek,Eunice S Wang,Steven D Green
Sawyer J Bawek
Mixed-phenotype acute leukemia (MPAL) is a rare form of leukemia with ambiguous lineage, and there are challenges in accurately diagnosing this entity according to formal criteria. Here we report a case which was initially diagnosed as "AML...
A rare case of Blastic plasmacytoid dendritic cell neoplasm with gynecologic presentation [0.03%]
以妇科表现为特征的树突细胞肿瘤一例报告
Marzouk Khouloud,Slama Nader,Bellalah Ahlem et al.
Marzouk Khouloud et al.
Blastic plasmacytoid dendritic cell neoplasm (BPDCN) is a rare hematological malignancy characterized by the proliferation of plasmacytoid dendritic cells with a blast-like appearance. It usually presents in elderly people, and clinical man...
Cup-like nuclei in adult B-cell acute lymphoblastic leukemia with the translocation (4;11)(q21;q23) [0.03%]
伴有(4;11)(q21;q23)易位的成人前体B细胞急性淋巴细胞白血病中的杯状核现象报告两例并文献复习
Yuyang Lu,Xinran Feng,Fengyu Chen
Yuyang Lu
Cuplike Nuclei(CLN) cells, particularly rare in Acute Lymphoblastic Leukemia(ALL), have been documented in only few cases to date. A recent study has revealed a correlation between CLN and IKZF1 deletions in pediatric B-ALL. This study intr...
A comprehensive case study on successful multimodal therapy in philadelphia chromosome-positive acute myeloid leukemia with NPM1 and IDH2 mutations [0.03%]
携带NPM1和IDH2基因突变的Ph阳性急性髓系白血病综合模态成功治疗病例报告
Syed Muhammad Waqar Haider,Mehwish Zehra,Nikesh N Shah et al.
Syed Muhammad Waqar Haider et al.
A 67-year-old female came to Tampa General Hospital with Philadelphia chromosome-positive (Ph+) acute myeloid leukemia (AML) featuring an intriguing combination of mutations, including NPM1 and IDH2 mutations. Novel combination therapy with...
Extramedullary plasmacytoma of the orbit complicating the evolution of multiple myeloma in complete remission [0.03%]
缓解期多发性骨髓瘤的眼眶外胚窦肿瘤变并发症病例报告
Nader Slama,Inaam Bizid,Ahlem Bellalah et al.
Nader Slama et al.
Orbital plasmacytoma is rare and has only been reported in the context of the initial diagnosis of multiple myeloma. Moreover, isolated orbital plasmacytoma without any signs of multiple myeloma is extremely rare. We report the case of a 59...
Treatment of relapsed/refractory chronic lymphocytic leukemia with Zanubrutinib after progressing on other BTK inhibitors [0.03%]
继其他布鲁顿酪氨酸激酶抑制剂进展后使用zanubrutinib治疗复发/难治性慢性淋巴细胞白血病
Nkolika Nwankwo,Aswanth Reddy,Swarup Kumar et al.
Nkolika Nwankwo et al.
Chronic Lymphocytic Leukemia (CLL) is the most common type of leukemia in the US, representing approximately 1.1% of all new cancers diagnosed. Most patients with CLL can be monitored without treatment, and the indicated treatment options i...
Late-onset Familial Hemophagocytic Lymphohistiocytosis in a survivor of Hodgkin's Lymphoma [0.03%]
霍奇金淋巴瘤幸存者晚期发作的家族性噬血细胞综合征病例报告
Mirza Rameez Samar,Daania Shoaib,Nida E Zehra et al.
Mirza Rameez Samar et al.
Hemophagocytic Lymphohistiocytosis is an inflammatory condition which results in over activation of the immune system. It could be either sporadic or familial. The familial subtype is linked with various genetic mutations and is commonly a ...