Targeting menin for precision therapy in high-risk acute myeloid leukemia [0.03%]
靶向MENIN对高危急性髓系白血病的精准治疗
Abdur Jamil,Zaheer Qureshi,Zain Mary El-Amir et al.
Abdur Jamil et al.
Objective: This mini-review provides an overview of the current evidence for Revumenib, a first-in-class menin inhibitor, in treating AML with KMT2A rearrangements or NPM1 mutations. This therapy represents a promising ad...
Retrospective claims data analysis of ASCT characteristics and costs for working-age, multiple myeloma patients in the US, 2017-2019 [0.03%]
美国2017至2019年工作年龄的多发性骨髓瘤自体干细胞移植特征和费用的回顾性理赔数据分析
Whanhui Chi,Juhyeon Song,Tyler J Varisco
Whanhui Chi
Multiple myeloma (MM) is a rare hematologic malignancy with a 5-year survival rate of 52 %. For transplant-eligible MM patients, high-dose chemotherapy followed by autologous stem cell transplant (ASCT) is recommended. Given the complexitie...
When the mask slips: A peripheral T-cell lymphoma disguised as lupus with myelofibrosis in a patient with May-Hegglin syndrome [0.03%]
当伪装失效时：一位患有May-Hegglin综合征的患者中，外周T细胞淋巴瘤被红斑狼疮和骨髓纤维化掩盖
V Da Silva Constante,H Couvert,A Wolfromm et al.
V Da Silva Constante et al.
We describe the case of a female patient with May-Hegglin syndrome who developed peripheral T-cell lymphoma not otherwise specified. The patient presents with systemic lupus erythematous phenotype and myelofibrosis secondary to T-cell lymph...
Acute lower limb ischemia revealing hypo granular acute promyelocytic leukemia [0.03%]
急性下肢缺血伴原粒细胞缺乏的急性早幼粒细胞白血病
Sabrina Belmahi,Zainab Kajeiou,Loubna Yacoubi et al.
Sabrina Belmahi et al.
Introduction: Acute promyelocytic leukemia (AML-M3), classified as acute Myeloid leukemia with PML RARA according to the 5th edition of the World Health Organization classification of haematolymphoid tumors 2022 [1], is m...
Management of hemolytic transfusion reactions in a patient with chronic myelomonocytic leukemia and rare antibodies: A case report [0.03%]
一例慢性粒单细胞白血病罕见抗体患者的溶血性输血反应管理：病例报告
Grace S Park,Himachandana Atluri,Courtney D DiNardo et al.
Grace S Park et al.
Delayed hemolytic transfusion reaction (DHTR) poses a significant challenge in patients receiving blood transfusions. This case report highlights the complexities of managing DHTR in a newly diagnosed chronic myelomonocytic leukemia (CMML) ...
Treatment of Vietnamese patients diagnosed with myelodysplastic neoplasms: Practical experience in a developing country [0.03%]
越南MDS患者治疗：发展中国家的实践经验分析
Quang Hao Nguyen,Minh Phuong Vu,Ha Trang Kieu et al.
Quang Hao Nguyen et al.
Background: Treatment of patients diagnosed with myelodysplastic neoplasms (MDS) is difficult and the outcome is still limited, especially in developing countries. We conducted this study in order to share some experience...
First-line therapy with daratumumab, lenalidomide and dexamethasone for patient with POEMS syndrome: A case report [0.03%]
达托慕单抗、来那度胺和地塞米松作为POEMS综合征一线疗法的案例报告
E Amabile,F Fazio,M Martelli et al.
E Amabile et al.
POEMS syndrome (polyneuropathy, organomegaly, endocrinopathy, M-protein, skin changes syndrome) is a rare condition due to an underlying plasma cell neoplasm whose clinical presentation can be various so it could lead to delayed diagnosis a...
Indolent infections in patients with hematologic malignancy: A single-center experience screening for tuberculosis and strongyloidiasis prior to cytotoxic therapy in Boston [0.03%]
造血恶性肿瘤患者中的惰性感染——波士顿一所医院在细胞毒性治疗前筛查结核和盘尾丝虫病的经验
K A Reifler,T Francoeur Smith,G Bodanapu et al.
K A Reifler et al.
Individuals with hematologic malignancy have increased risk of latent tuberculosis infection (LTBI) reactivation and Strongyloides stercoralis (SS) dissemination. However, screening prior to chemotherapy or corticosteroids is not routine. W...
An uncommon triad of myelodysplastic syndrome, Crohn's disease and autoimmune hepatitis: A case report and review of the literature [0.03%]
一种罕见的骨髓增生异常综合征、克罗恩病和自身免疫性肝炎三联征：病例报告及文献回顾
Arij Cheffai,Wiem Boufrikha,Rim Rakez et al.
Arij Cheffai et al.
Myelodysplastic syndrome (MDS) is associated with an autoimmune disease (AD) in 10 to 20% of cases. Crohn's disease (CD) is not a common autoimmune manifestation reported with MDS. The triad made up of MDS, CD and another autoimmune manifes...
A rapid progression from classical mantle cell lymphoma to a blastoid variant [0.03%]
经典型套细胞淋巴瘤迅速进展为blastoid变异型
Radu Chiriac,Marie Donzel,Lucile Baseggio
Radu Chiriac
This case report presents an 82-year-old male initially diagnosed with classical mantle cell lymphoma (MCL) that progressed to the aggressive blastoid variant. The patient was initially treated with oral chemotherapy (PEP-C), followed by ib...