Fecal microbiota transplantation: History, procedure and regulatory considerations [0.03%]
粪菌移植：历史、流程与监管考量
Thanush D,M P Venkatesh
Thanush D
Fecal microbiota transplantation (FMT) is a medical treatment which involves the transfer of feces from a healthy donor to a recipient to restore the balance of gut microbiota and improve clinical outcomes. FMT has gained recognition in rec...
Philippe Connes,Céline Renoux,Philippe Joly et al.
Philippe Connes et al.
Sickle cell disease (SCD) is an hereditary disorder characterized by the production of an abnormal hemoglobin called hemoglobin S (HbS). HbS may polymerize in deoxygenated conditions, which leads to red blood cell (RBC) sickling. Sickled RB...
Julie Carrara,Anoosha Habibi,Alexandra Benachi et al.
Julie Carrara et al.
Pregnancy is a particularly risky period in the life of patients with sickle cell disease (SCD). Physiological changes during pregnancy increase the risk of vaso-occlusive crises (VOC), acute chest syndrome, venous thromboembolic events, an...
Prevention of neurovascular complications in children with Sickle Cell Disease in the real-world setting: What adult medicine physicians should know [0.03%]
实际情况下预防镰状细胞病患儿的神经血管并发症：内科医生应该了解什么
Giulia Reggiani,Maria Paola Boaro,Raffaella Colombatti
Giulia Reggiani
Neurovascular complications represent one of the most detrimental manifestations of Sickle Cell Disease (SCD), affecting many patients since infancy. They include overt stroke, silent cerebral infarcts and neurocognitive disorders. In fact,...
Electrical therapies in heart failure: Evolving technologies and indications [0.03%]
心力衰竭中的电学治疗：技术发展及应用指征
Cecilia Linde
Cecilia Linde
Device therapy for heart failure has rapidly evolved over 2 decades. The knowledge of indications, assessment lead and device technology has expanded to include CRT, leadless pacing and conduction system pacing such as His bundle and left b...
End-stage heart failure: The future of heart transplant and artificial heart [0.03%]
终末期心力衰竭：心脏移植与人工心脏的未来方向
Karl Bounader,Erwan Flécher
Karl Bounader
In the last decades, outcomes significantly improved for both heart transplantation and LVAD. Heart transplantation remains the gold standard for the treatment of end stage heart failure and will remain for many years to come. The most rele...
Heart failure with preserved ejection fraction: New challenges and new hopes [0.03%]
射血分数保留的心力衰竭：新的挑战与新的希望
Damien Logeart
Damien Logeart
Heart failure (HF) is a major public health problem affecting millions of adults worldwide. HF with preserved ejection fraction, i.e. > 50 %, (HFpEF) accounts for more than half of all HF cases, and its incidence and prevalence are increasi...
Ayu Asakage,Alexandre Mebazaa,Benjamin Deniau
Ayu Asakage
Acute heart failure (AHF) is a clinical complex disease and a worldwide issue due to its inconsistent diagnosis and poor prognosis. The cornerstone of pathophysiology of AHF is systemic venous congestion, which is led by the underlying stru...
Epistemological challenges for neural correlates of consciousness: A defense of medical research on consciousness [0.03%]
论意识神经相关研究的科学地位
Armance Neveu,Vincent Degos,Anouk Barberousse
Armance Neveu
Recent work in the field of consciousness science has predominantly focused on the search for neural correlates of consciousness (NCC). However, despite significant technological advances in recent decades, defining NCC remains an ambitious...
Disorders of Consciousness: navigating between nihilism and unrealistic hopes [0.03%]
意识障碍：在虚无主义与不切实际的希望之间寻求平衡
Benjamin Rohaut
Benjamin Rohaut