Mark G Evans,Anthony Crymes,Adam Bedeir et al.
Mark G Evans et al.
Adult granulosa cell tumor (GCT) is an uncommon sex cord-stromal neoplasm of the ovary. It typically demonstrates locoregional spread, and disease outside of the pelvis as metastasis is uncommon. Only a rare case of primary thoracic adult G...
Severe denosumab-induced hypocalcemia requiring long-term intensified medication in a patient with EGFR-mutant lung cancer and diffuse osteoblastic bone metastases [0.03%]
EGFR突变型肺癌和广泛性成骨性骨转移患者出现严重denosumab诱导的低钙血症，需要长期强化治疗
Masayuki Mori,Masayuki Shirasawa,Akihito Oguri et al.
Masayuki Mori et al.
Lung cancer often causes bone metastasis, and denosumab is administered to bone metastases to prevent bone-related adverse events. One of the important side effects of denosumab is hypocalcemia, but this is generally not a problem, as it is...
New onset bronchial asthma following oral propranolol for infantile hemangioma [0.03%]
婴儿血管瘤口服普萘洛尔后新发支气管哮喘
Yuki Yamaguchi,Satoshi Horino,Hiroki Miyabayashi et al.
Yuki Yamaguchi et al.
Propranolol, a nonselective adrenergic beta-receptor blocker, is the first-line drug used for the treatment of infantile hemangiomas (IH). However, its use is contraindicated in patients with bronchial asthma. Nevertheless, studies assessin...
Bilal Alqam,Sarah Medrek
Bilal Alqam
An 81-year-old man with a history of interstitial lung disease attributed to idiopathic pulmonary fibrosis, severe aortic stenosis, and stable coronary artery disease was started on inhaled treprostinil for pulmonary hypertension associated...
Efficacy and safety of lenvatinib in a case of thymic carcinoma complicated with interstitial lung disease and anti-melanoma differentiation-associated gene 5 antibody-positive dermatomyositis: A case report [0.03%]
仑伐替尼治疗合并间质性肺疾病和抗黑色素瘤分化相关基因5抗体阳性皮肤炎肌炎的胸腺癌一例：病例报告iệu
Yuki Hatakeyama,Jun Sakakibara-Konishi,Masato Tarumi et al.
Yuki Hatakeyama et al.
Based on the results of a multicenter phase II study of patients with previously treated thymic carcinoma, lenvatinib administration for unresectable thymic cancer has been covered under insurance in Japan since 2021. However, patients with...
Allergic bronchopulmonary mycosis induced by pembrolizumab for bladder cancer: A case report [0.03%]
派姆单抗治疗膀胱癌导致的过敏性支气管肺真菌病：病例报告
Hiroki Iida,Kenichiro Atsumi,Naohiro Kadoma et al.
Hiroki Iida et al.
Pembrolizumab is an immune checkpoint inhibitor (ICI) of programmed cell death-1 category, used for treating various types of cancer. ICIs can sometimes result in immune-related adverse events. Allergic bronchopulmonary mycosis (ABPM) induc...
Pulmonary artery aneurysm as a rare manifestation of Alpha-1 antitrypsin deficiency [0.03%]
α抗胰蛋白酶缺乏症的一种罕见表现：肺动脉瘤
Mark A Colantonio,Sanjana Aggarwal,Himanshu Deshwal
Mark A Colantonio
Alpha-1 antitrypsin is a relatively well-known genetic disease known to primarily affect the lungs and liver. Extrapulmonary manifestations of this disease have been reported, including vascular aneurysms. To date, few cases have reported v...
Pulmonary vascular malformations in genetic epileptic encephalopathy: A rare, fatal case report [0.03%]
遗传性癫痫脑病中的肺血管畸形：一项罕见的死亡病例报告
N Garancini,M Ghezzi,A Farolfi et al.
N Garancini et al.
Mutations of KCNT1 gene, encoding for a sodium-gated potassium channel, are causative of a wide spectrum of epilepsies and neurodevelopmental disorders; cardiovascular involvement also seems to be significant, with cardiac arrhythmia and, l...
Reduced tracheal stenosing effect of nintedanib in a patient with scarred posttraumatic tracheal stenosis and airflow limitation - a case report [0.03%]
对于有瘢痕性创伤气管狭窄和气流受限的患者，尼达尼布的气管缩窄作用降低-病例报告
Stefanie Klampfleitner,Andreas Fertl,Ositha Prinz et al.
Stefanie Klampfleitner et al.
Introduction: Nintedanib is a tyrosine kinase inhibitor and has been approved for the treatment of idiopathic pulmonary fibrosis (IPF) since 2020. In Clinical trials, the antifibrotic effect of nintedanib was shown. ...
Idiopathic CD4 lymphocytopenia: An uncommon but fatal cause of Pneumocystis pneumonia [0.03%]
原因不明的CD4淋巴细胞减少症：一种罕见但致死的肺炎病因
Julia Schearer,Christopher Merrick
Julia Schearer
Pneumocystis pneumonia (PCP) is a fungal infection with primary occurrence in immunocompromised individuals by the etiologic agent Pneumocystis jirovecii. In those without previously identified risk factors, maintaining an index of suspicio...