Expression profile of Rab5, Rab7, tryptophan aspartate-containing coat protein, leprae lipoarabinomannan, and phenolic glycolipid-1 on the failure of the phagolysosome process in macrophages of leprosy patients as a viability marker of Mycobacterium leprae [0.03%]
麻风患者巨噬细胞溶酶体吞噬过程失败的表达谱系：作为麻风杆菌活力标记的Rab5、Rab7、含色氨酸丝氨酸衣被蛋白、结核分枝杆菌脂阿拉伯甘露糖和苯酚甘油基脂-1的作用
Cita Rosita Sigit Prakoeswa,Ratna Wahyuni,Iswahyudi et al.
Cita Rosita Sigit Prakoeswa et al.
Objective/background: Phagolysosome process in macrophage of leprosy patients' is important in the early phase of eliminating Mycobacterium leprae invasion. This study was to clarify the involvement of Rab5, Rab7, and try...
Use of RODAC plates to measure containment of Mycobacterium tuberculosis in a Class IIB biosafety cabinet during routine operations [0.03%]
RODAC平板法检测Ⅱ级生物安全柜内常规操作中结核分枝杆菌的泄漏情况
Géraldine Daneau,Elie Nduwamahoro,Kristina Fissette et al.
Géraldine Daneau et al.
Objective/background: Guidelines for the manipulation of Mycobacterium tuberculosis (MTB) cultures require a Biosafety Level 3 (BSL-3) infrastructure and accompanying code of conduct. In this study, we aimed to validate a...
K N&#x;guessan Kouassi,Alagna Riccardo,C Dutoziet Christian et al.
K N&#x;guessan Kouassi et al.
Objective/background: Tuberculosis remains an important cause of mortality worldwide. Previous tuberculosis treatment is a strong determinant of multi-drug resistant tuberculosis. The study objective was to describe the m...
Mycobacterium leprae specific genomic target in the promoter region of probable 4-alpha-glucanotransferase (ML1545) gene with potential sensitivity for polymerase chain reaction based diagnosis of leprosy [0.03%]
麻风分枝杆菌基因ML1545(假定的4-葡萄糖转移酶基因)启动子区PCR诊断靶点的筛选与鉴定
V Sundeep Chaitanya,Madhusmita Das,Tiffany L Eisenbach et al.
V Sundeep Chaitanya et al.
With the absence of an effective diagnostic tool for leprosy, cases with negative bacteriological index and limited clinical manifestations often pose diagnostic challenges. In this study, we investigated the utility of a novel Mycobacteriu...
A cross-sectional study about knowledge and attitudes toward multidrug-resistant and extensively drug-resistant tuberculosis in a high-burden drug-resistant country [0.03%]
耐多药和广泛耐药结核病知识和态度的横断面研究——来自高负担国家的数据
Hasnain Javed,Zarfishan Tahir,Hafiza Jawairia Hashmi et al.
Hasnain Javed et al.
Objective/background: Tuberculosis (TB) is a leading cause of death worldwide, with new threats of multidrug-resistant (MDR) and extensively drug-resistant (XDR) TB. Pakistan is the fifth highest among high-burden TB coun...
Selection of phage-displayed human antibody fragments specific for CD1b presenting the Mycobacterium tuberculosis glycolipid Ac2SGL [0.03%]
人源抗体片段文库筛选结合MTB特异性脂类抗原Ac2SGL-CD1b复合物的抗体分子
Frank Camacho,María E Sarmiento,Fatima Reyes et al.
Frank Camacho et al.
Objective/background: The development of new tools capable of targeting Mycobacterium tuberculosis (Mtb)-infected cells have potential applications in diagnosis, treatment, and prevention of tuberculosis. In Mtb-infected ...
Association of plasma cytokines with radiological recovery in pulmonary tuberculosis patients [0.03%]
肺结核患者的血浆细胞因子与影像学恢复之间的关联
Najeeha Talat Iqbal,Rabia Hussain,Firdaus Shahid et al.
Najeeha Talat Iqbal et al.
Objective/background: The characterization of tuberculosis (TB) patients as slow or fast responders post anti-TB treatment has always been a matter of tremendous interest as slow responders are most likely to relapse and/...
Meropenem-clavulanate has high in vitro activity against multidrug-resistant Mycobacterium tuberculosis [0.03%]
美罗培南-克拉维酸对耐多药结核分枝杆菌具有较强的体外活性
L Davies Forsman,C G Giske,J Bruchfeld et al.
L Davies Forsman et al.
Aims and objectives: With the relentless increase in multidrug- and extensively-drug resistant tuberculosis (MDR/XDR-TB), new treatment strategies are necessary. Favorable results have been reported by combining a β-lact...
Molecular structure of Mycobacterium tuberculosis population in Russia and its interaction with neighboring countries [0.03%]
俄罗斯结核分枝杆菌分子结构及其与周边国家的关系探究
I Mokrousov
I Mokrousov
Background: The tuberculosis (TB) situation in Russia is aggravated by the emergence and the spread of multidrug-resistant strains, HIV co-infection and drawbacks in the health control system. The Mycobacterium tuberculos...
Fluoroquinolone resistance in Mycobacterium tuberculosis isolates from Pakistan 2010-2014: Implications for disease control [0.03%]
巴基斯坦（2010-2014年）结核分枝杆菌耐氟喹诺酮情况及其对疾病控制的影响
Kausar Jabeen,Sadia Shakoor,Faisal Malik et al.
Kausar Jabeen et al.
Introduction: Fluoroquinolones (FQ) are an essential component of current and new regimens for the treatment of tuberculosis (TB). The 2014 Global TB report indicates a FQ resistance rate of 17% amongst multidrug-resistan...