Potential Role of Whole Genome Sequencing to Predict the Virulence, Anti-TB Resistance, and Variants of Mycobacterium tuberculosis Strains from Rifampicin-sensitive Pulmonary Tuberculosis Patients in Surabaya, East Java, Indonesia [0.03%]
万基测序预测印度尼西亚东爪哇泗水市利福平敏感性肺结核患者中结核分枝杆菌毒力、抗药性和菌株变异的潜在作用
Ni Made Mertaniasih,Muhamad Frendy Setyawan,Ummi Amaliatush Sholichah Putri Merdekawati et al.
Ni Made Mertaniasih et al.
Background: Tuberculosis (TB) is the second concern of a fatal infectious disease in the world caused by Mycobacterium tuberculosis (MTB). Indonesia has many regions that is known as a hotspot region for MTB cases, one of...
Causes and Management of Chest Computed Tomography Lesions Progression in Pulmonary Tuberculosis during Antituberculosis Treatment [0.03%]
抗结核治疗过程中肺结核胸部CT病灶演变的原因及处理措施分析
Shuangyin Yang,Yanmei Feng,Kuiliang Yang et al.
Shuangyin Yang et al.
Background: Even with early antituberculosis (TB) treatment, some patients with pulmonary TB (PTB) may experience progression of chest computed tomography (CT) lesions. However, there is limited information on the causes ...
Dynamics of the In vitro Growing of Mycobacterium bovis from the Lungs of Vaccinated and Infected Mice [0.03%]
结核分枝杆菌在接种疫苗和感染小鼠体外培养中的生长动力学研究
Federico Carlos Blanco,Laura Inés Klepp,Cristina Lourdes Vazquez et al.
Federico Carlos Blanco et al.
Background: Bovine tuberculosis (bTB) is a disease primarily caused by Mycobacterium bovis. Currently, no commercial vaccines exist for controlling bTB, making the development of effective vaccine candidates and testing m...
Evolutionary Genetic Analysis of the Pyrazinamidase Gene in Seven Global Populations of Mycobacterium tuberculosis [0.03%]
鸟分枝杆菌在全球七个地区人群中的进化遗传分析
Neha Kumari,Nikhat Khan,Aparup Das
Neha Kumari
Background: This study aims to identify the signatures of natural selection in the pyrazinamidase (pncA) gene to see if genetic adaptations by Darwinian natural selection have shaped genetic composition of Mycobacterium t...
Clinical Profile, Outcomes, and Predictors of Outcomes in Patients with Tuberculosis with Arachnoiditis [0.03%]
结核性蛛网膜炎患者的临床特征、结局及预后影响因素分析
David Mathew Daniel,Samuel George Hansdak,Tina George et al.
David Mathew Daniel et al.
Background: Tuberculosis (TB) remains a leading global cause of infectious disease-related mortality. This study aimed to investigate the clinical characteristics, outcomes, and prognostic factors in patients diagnosed wi...
Molecular Detection of Gene Mutation Related to Drug Resistance in Mycobacterium leprae [0.03%]
麻风分枝杆菌耐药相关基因突变的分子检测方法研究进展
Saumya Shukla,Shaina Gaikwad,Dhandapani Sureshgopi et al.
Saumya Shukla et al.
Background: Mycobacterium lepare-induced leprosy continues to pose a significant public health threat. Drug-resistant strains pose a major challenge for effective management, necessitating molecular studies to identify re...
Diagnostic Modalities for Detecting Extrapulmonary Tuberculosis and Resistance Patterns of Rifampicin and Isoniazid at a Referral Hospital: A Retro Prospective Study [0.03%]
诊断肺外结核的检测方法及利福平和异烟肼耐药模式：一项回顾性研究
Ankur Kumar,Amresh Kumar Singh,Vivek Gaur et al.
Ankur Kumar et al.
Background: Tuberculosis (TB), caused by Mycobacterium tuberculosis complex, results in approximately 1.5 million annual deaths globally. Diagnosing extrapulmonary TB (EPTB) remains challenging due to the invasive nature ...
Mitigating Tuberculosis Drug-induced Liver Injury: The Role of Moringa oleifera and Other Herbal Extracts [0.03%]
利用摩尔吉亚叶和其他草药提取物减轻结核病药物引起的肝损伤
Herin Mawarti,Khotimah Khotimah,Yuly Peristiowati et al.
Herin Mawarti et al.
Background: Tuberculosis (TB) is a significant public health issue, and drug-induced liver injury (DILI) from anti-TB medications poses a major challenge to treatment efficacy. This study aims to evaluate the protective e...
The Effect of Sex on Active and Latent Tuberculosis Occurrence Based on Mannose-Binding Lectin 2 Gene Expression and Mannose-binding Lectin Plasma Concentration in Indonesia [0.03%]
基于结合凝集素2基因表达和岩藻糖结合凝集素血浆浓度的印尼活动性和潜在性肺结核发病的性别差异研究
Yanti Leman,Muhammad Nasrum Massi,Peter Kabo et al.
Yanti Leman et al.
Background: Studies on the role of mannose-binding lectin 2 (MBL2) in individuals infected with tuberculosis (TB) remain limited. This study aimed to compare MBL2 gene expression and protein concentration between active a...
Studying the Effect of Tumor Necrosis Factor-Alpha and Tumor Necrosis Factor Gene Polymorphisms on the Incidence of Tuberculosis [0.03%]
肿瘤坏死因子-α和肿瘤坏死因子基因多态性对结核发病影响的调查研究
Jalaledin Ghanavi,Poopak Farnia
Jalaledin Ghanavi
Tuberculosis and its pathogen, Mycobacterium tuberculosis complex, are a major health challenge. The causative agent of tuberculosis is M. tuberculosis complex and is transmitted through airborne droplets. Tumor necrosis factor-alpha (TNF-...