Epidemiology of Tuberculosis in Qatar: Eight-year Retrospective Cohort Study [0.03%]
卡塔尔结核病流行病学：八年回顾队列研究
Joanne Daghfal,Sara Al Balushi,Masautso Chaponda et al.
Joanne Daghfal et al.
Background: Tuberculosis (TB) remains a major global health challenge, responsible for substantial morbidity and mortality. Understanding national epidemiological patterns, particularly in countries with large expatriate ...
Reuse of Residual DNA Eluates from TrueNat™ Testing for Mycobacterium tuberculosis Complex Subspecies Differentiation: A Proof-of-concept Implementation Feasibility Study [0.03%]
一项概念验证实施可行性研究：重复利用TrueNatTM检测后的残留DNA洗脱液进行结核分枝杆菌复合群种间鉴别
Hindol Maity,Keshao Hiwale,Supriya Meshram et al.
Hindol Maity et al.
Background: The Mycobacterium tuberculosis complex (MTBC) includes human-and animal-adapted species. Routine TrueNat™ testing detects MTBC but does not differentiate subspecies. This study evaluated the reuse of residual...
Genotypic Characterization of Drug Resistance-associated Mutations in Mycobacterium tuberculosis Using Line Probe Assays in Central India [0.03%]
中央印度地区利用线探针测定技术对结核分枝杆菌耐药相关突变的基因表型特征分析
Antisha Tiwari,Shaina Gaikwad,Vishal Dangi et al.
Antisha Tiwari et al.
Background: Drug-resistant tuberculosis (TB), especially rifampicin-resistant and multidrug-resistant TB, remains a significant public health challenge worldwide. Rapid and accurate methods for molecular diagnostics, such...
Comparative Evaluation of Fluorescein Diacetate/Ethidium Bromide Viability Microscopy and Ziehl-Neelsen Staining for Rapid Diagnosis of Pulmonary Tuberculosis [0.03%]
荧光素二醋酸酯/溴已新活力显微镜与抗酸染色法快速诊断肺结核的比较研究
Shubhendu Singh,Dakshina Bisht,Ajoy Kumar Verma et al.
Shubhendu Singh et al.
Background: Ziehl-Neelsen (ZN) staining is routinely used for tuberculosis (TB) diagnosis, but cannot differentiate viable from nonviable bacilli. This limitation is particularly relevant in smear-positive pulmonary TB pa...
Diabetes-associated Phenotypic Masking of Fluoroquinolone Resistance in Multidrug-resistant Tuberculosis: Evidence from Genotypic-Phenotypic Discordance in Surabaya, Indonesia [0.03%]
糖尿病掩盖了印度尼西亚泗水市多药耐药结核分枝杆菌的氟喹诺酮类药物抗性：来自基因型和表型不一致的证据
Lyndia Effendy,Ni Made Mertaniasih,Soedarsono Soedarsono et al.
Lyndia Effendy et al.
Background: Emerging fluoroquinolone (FQ) resistance threatens multidrug-resistant tuberculosis (MDR-TB) management, complicating access to shorter regimens. This study characterizes FQ-resistant TB (FQ-R-TB) patients in ...
Depression Level and Quality of Life between Shorter and Longer Regimens among Patients with Multidrug-resistant Tuberculosis [0.03%]
耐多药结核病短程和长程方案患者抑郁水平及生活质量比较研究
Oki Nugraha Putra,Nur Indah,Nurul Damayanti
Oki Nugraha Putra
Background: This study estimated the prevalence of depression among Indonesian multidrug-resistant tuberculosis (MDR-TB) patients and quality of life (QoL) between shorter and longer regimens, as well as factors associate...
Drug Reaction with Eosinophilia and Systemic Symptoms Syndrome in Pulmonary Tuberculosis Patient with Type 2 Respiratory Failure and Sepsis [0.03%]
合并二型呼吸衰竭及脓毒症的肺结核患者发生药物反应伴嗜酸性粒细胞增多和系统性症状综合征
Brigita Sanina Manullang,Isnin Anang Marhana
Brigita Sanina Manullang
While anti-tuberculosis drugs (ATDs) are essential for tuberculosis (TB) treatment, they can induce severe hypersensitivity reactions, including drug reaction with eosinophilia and systemic symptoms (DRESS) syndrome. Its occurrence presents...
Mesenchymal Stem Cell-derived Exosomes for the Treatment of Bronchiectatic Nontuberculous Mycobacterial Pulmonary Disease [0.03%]
间充质干细胞衍生的外泌体治疗支气管扩张型非结核分枝杆菌肺病
Gaoxiang Wu,Fei He
Gaoxiang Wu
Nontuberculous mycobacterial pulmonary disease (NTM-PD) is a chronic and challenging infectious condition with rising global prevalence, and its bronchiectatic subtype is particularly difficult to treat with conventional regimens due to fre...
Leishmaniasis Masquerading as Lepromatous Leprosy: A Rare Dermatological Diagnostic Pitfall [0.03%]
误诊为瘤型梅毒的皮肤黏膜利什曼病——一种罕见的皮肤病诊断陷阱
Madhuri Singh,Shirish S Chandanwale,Sushama Gurwale et al.
Madhuri Singh et al.
Dermal leishmaniasis, particularly postkala-azar dermal leishmaniasis (PKDL), is an uncommon entity that may closely mimic lepromatous leprosy in endemic regions. Both conditions present with chronic, symmetric nodular or plaque-like lesion...
Investigation of In vitro Efficacy of New Generation Drugs Tedizolid and Omadacycline against Nontuberculous Mycobacteria [0.03%]
特地唑和奥马扎 cycline 体外对抗非结核分枝杆菌疗效的研究
Seda Türkkal Arli,Nazli Ece Özçatalkaya,Elif Çiftçi et al.
Seda Türkkal Arli et al.
Background: Species-specific antimicrobial susceptibility testing is crucial for the effective treatment of nontuberculous mycobacteria (NTM). In this study, the in vitro antimicrobial activities of two next-generation an...