Factors associated with treatment success and death in cases with multidrug-resistant tuberculosis in Bulgaria, 2009-2010 [0.03%]
2009-2010年保加利亚耐多药肺结核治疗成功与死亡的相关因素分析
Vladimir Milanov,Dennis Falzon,Mariya Zamfirova et al.
Vladimir Milanov et al.
Objective: To analyze determinants of success and death in multidrug-resistant tuberculosis patients (MDR-TB; resistance to, at least, isoniazid and rifampicin) placed on treatment in Bulgaria during the period September ...
Immunoconfirmation of central nervous system tuberculosis by blotting: A study of 300 cases [0.03%]
300例中枢神经系统结核的免疫证实研究
Shripad Patil,Prashant Giribhattanavar,Madhusudan Patil et al.
Shripad Patil et al.
Tuberculous meningitis (TBM) is a serious form of disease of the central nervous system. Early and accurate diagnosis of the disease and effective treatment are key important factors to contain the disease. The disease presents as chronic m...
Joseph Mwanzia Nguta,Regina Appiah-Opong,Alexander K Nyarko et al.
Joseph Mwanzia Nguta et al.
Aims: The current study was designed to document medicinal plant species that are traditionally used to treat tuberculosis (TB) by Ghanaian communities. M...
Benzothiazinone-piperazine derivatives as efficient Mycobacterium tuberculosis DNA gyrase inhibitors [0.03%]
作为高效抗结核杆菌DNA解旋酶抑制剂的苯并噻唑酮-哌嗪类衍生物
Manoj Chandran,Janupally Renuka,Jonnalagadda Padma Sridevi et al.
Manoj Chandran et al.
Background and objectives: Bacterial DNA topoisomerases are unique in maintaining the DNA topology for cell viability. Mycobacterium tuberculosis (MTB) DNA gyrase, a sole type II topoisomerase has a larger scope as a targ...
E84G mutation in dihydrofolate reductase from drug resistant strains of Mycobacterium tuberculosis (Mumbai, India) leads to increased interaction with Trimethoprim [0.03%]
来自印度孟买耐药结核分枝杆菌株的二氢叶酸还原酶(E84G)突变体与甲氧苄氨嘧啶的相互作用增强
Archana Raju,Savita Kulkarni,M K Ray et al.
Archana Raju et al.
Background: Dihydrofolate reductase (DHFR) (dfrA gene) is an essential enzyme for cell survival and an unexplored target in Mycobacterium tuberculosis (Mtb). This study was carried out to analyze mutations in the dfrA gen...
Samuel Halstrom,Patricia Price,Rachel Thomson
Samuel Halstrom
Pulmonary infections with nontuberculous mycobacteria (NTM) are recognized as a problem in immunodeficient individuals and are increasingly common in older people with no known immune defects. NTM are found in soil and water, but factors in...
Efficacy and safety of isoniazid preventive therapy in light of increasing multi-drug resistance in tuberculosis [0.03%]
结核病多重耐药性增加背景下异烟肼预防治疗的有效性和安全性
Lingaraja Jena,Bhaskar C Harinath
Lingaraja Jena
A 7-year-old girl with multiple skin ulcers: Case report and literature review [0.03%]
多发性皮肤溃疡患儿的临床病例及文献回顾
Eman Sobh,Amira Bahour,Sahar Elsayed et al.
Eman Sobh et al.
Introduction: There has been an increase in the number of tuberculosis (TB) cases worldwide, but TB of the skin remains rare. Case presentation: ...
Mohamed Ali Sbai,Sofien Benzarti,Monia Boussen et al.
Mohamed Ali Sbai et al.
Tuberculosis is a major public health problem in developing countries. Flexor tenosynovitis of the fingers constitutes an exceptional tuberculosis localization (Gabl et al., 1997; Senda et al., 2011) [1,2]. Unusual presentations, such as tu...
Sequence comparison of six human microRNAs genes between tuberculosis patients and healthy individuals [0.03%]
结核病患者与健康人六种人microRNAs基因的序列比较分析
A Amila,A Acosta,M E Sarmiento et al.
A Amila et al.
Objective/background: MicroRNAs (miRNAs) play an important role in diseases development. Therefore, human miRNAs may be able to inhibit the survival of Mycobacterium tuberculosis (Mtb) in the human host by targeting criti...