Computational approach to understanding the mechanism of action of isoniazid, an anti-TB drug [0.03%]
计算分析异烟肼的抗结核作用机制
Lingaraja Jena,Pranita Waghmare,Supriya Kashikar et al.
Lingaraja Jena et al.
Tuberculosis (TB) is an ancient disease caused by Mycobacterium tuberculosis (MTB), which remains a major cause for morbidity and mortality in several developing countries. Most drug-resistant MTB clinical strains are resistant to isoniazid...
Barriers to access to antiretroviral treatment for HIV-positive tuberculosis patients in Windhoek, Namibia [0.03%]
纳米比亚温得和克艾滋病阳性肺结核病人接受抗逆转录病毒治疗的障碍分析
Stefanie Seeling,Farai Mavhunga,Albertina Thomas et al.
Stefanie Seeling et al.
Setting: Namibia faces a high burden of tuberculosis (TB) and HIV-infection. In 2011, 50% of the TB patients were co-infected with HIV. While all patients co-infected with TB and HIV are eligible for antiretroviral treatm...
Optimization and validation of Mycobacterium marinum-induced adult zebrafish model for evaluation of oral anti-tuberculosis drugs [0.03%]
优化和验证用于评估口服抗结核药物的鱼藤酮诱导成年斑马鱼模型
Jonnalagadda Padma Sridevi,Hasitha Shilpa Anantaraju,Pushkar Kulkarni et al.
Jonnalagadda Padma Sridevi et al.
Introduction: Mycobacterium marinum has emerged as a suitable species for induction of tuberculosis-like disease in zebrafish, and various zebrafish models (larval and adult) for drug screening have been proposed in the l...
Polymerase Chain Reaction targeting insertion sequence IS6110 for the diagnosis of pulmonary tuberculosis among Sudanese children and young adults [0.03%]
针对插入序列IS6110的聚合酶链反应在苏丹儿童和年轻人中诊断肺结核的应用
Ahmed L Osman,Nageeb S Saeed,Mogahid M Elhassan
Ahmed L Osman
This study was carried out in Khartoum State during the period from January 2011 to December 2013 to improve the rate of detection of Mycobacterium tuberculosis (MTB) in children with symptoms of tuberculosis (TB) infection using different ...
Safety of the two-step tuberculin skin test in Indian health care workers [0.03%]
印度医务人员中两步结核菌素皮肤试验的安全性
Devasahayam J Christopher,Deepa Shankar,Ashima Datey et al.
Devasahayam J Christopher et al.
Background: Health care workers (HCW) in low and middle income countries are at high risk of nosocomial tuberculosis infection. Periodic screening of health workers for both TB disease and infection can play a critical ro...
E A R Edirisinghe,D R A Dissanayake,C L Abayasekera et al.
E A R Edirisinghe et al.
Nontuberculous mycobacteria (NTM) have been reported to cause opportunistic infections with increasing frequency, especially in immunocompromised patients. Water plays a major role in the epidemiology of nontuberculous mycobacterial infecti...
Resazurin microtiter assay for isoniazid, rifampicin, ethambutol and streptomycin resistance detection in Mycobacterium tuberculosis: Updated meta-analysis [0.03%]
用于检测结核分歧杆菌异烟肼、利福平、乙胺丁醇和链霉素耐药性的微孔板雷锁试剂试验:荟萃分析更新结果
Ahmet Yilmaz Coban,Aydin Deveci,Ahmet Tevfik Sunter et al.
Ahmet Yilmaz Coban et al.
Aims: The present meta-analysis aims to assess the evidence regarding the diagnostic accuracy and performance characteristics of the colorimetric redox indicator (CRI) assay with a special emphasis on the use of the resaz...
Sarcoidosis: Role of non-tuberculosis mycobacteria and Mycobacterium tuberculosis [0.03%]
肉芽肿性多angiitis的血管病变特征及治疗反应关系的研究
Esmaeil Mortaz,Ian M Adcock,Peter J Barnes
Esmaeil Mortaz
Sarcoidosis is a granulomatous inflammatory disease that is induced by unknown antigen(s) in a genetically susceptible host. Although the direct link between Mycobacterium tuberculosis (MTB) infection and sarcoidosis can be excluded on the ...
Pulmonary infection with caseating mediastinal lymphadenitis caused by Mycobacterium gordonae [0.03%]
戈登分枝杆菌所致肺感染伴肉芽肿性纵隔淋巴结炎病例报告
Dima Youssef,Wael E Shams,Yasmin Elshenawy et al.
Dima Youssef et al.
It is often difficult to discern true mycobacterial infection from colonization due to Mycobacterium gordonae (M. gordonae) since this organism is ubiquitous and is commonly an innocuous saprophyte. This study reports a rare case of caseati...
Rida-Allah Bassir,Fouad Saoudi,Farid Ismael et al.
Rida-Allah Bassir et al.
Bifocal musculoskeletal tuberculosis is a rare presentation of the disease. The following report documents the case of a 28-year-old Moroccan man presenting simultaneously with a swelling of the palm of the hand and the sternoclavicular joi...