Angiogenic Ability of Extracellular Vesicles Derived from Angio-miRNA-Modified Mesenchymal Stromal Cells [0.03%]
来源于血管生成miRNA修饰的间充质基质细胞的外泌体的血管生成能力
Yoshiki Wada,Toshifumi Kudo,Anri Koyanagi et al.
Yoshiki Wada et al.
Background: Regenerative therapy using extracellular vesicles (EVs) is a promising approach for the supportive treatment of chronic limb-threatening ischaemia. Herein, we examined the angiogenic potential of EVs derived f...
Effect of Solute Molecular Weights on Mass Transfer within the Rat Lacunar-Canalicular System under Gravity [0.03%]
重力对大鼠骨小管系统内不同分子量溶质传输的影响研究
Baochuan Xiong,Tianyu Liu,Yuxin Zhao et al.
Baochuan Xiong et al.
Background: The lacunar-canalicular system (LCS) serves as the mechanobiological foundation for bone tissue metabolism, mechanotransduction, and functional adaptation. However, the impact of solutes with varying molecular...
Human Nasal Olfactory Stem Cell-Derived Extracellular Vesicles Improve the Repair of Rat Nerves [0.03%]
人源鼻粘膜嗅鞘细胞来源的外泌体促进大鼠坐骨神经修复
Maxime Bonnet,Mostafa Seblani,Marie Witters et al.
Maxime Bonnet et al.
Background: Damage to the peripheral nerve significantly impairs quality and way of life. Despite the slow self-regeneration of the peripheral nervous system and advances in surgery, complete recovery after nerve injury r...
Angiopoietin-1 and Tie2-Based Dual Cell Therapy Enhances Antiangiogenic Barrier Function in a Retina-Mimetic Model for Neovascular Retinal Disease [0.03%]
血管内皮生长因子受体-3配体VEGF-D在乳腺癌转移中的作用
Cha Yeon Kim,Cholong Jeong,Youngjin Han et al.
Cha Yeon Kim et al.
Background: Choroidal neovascularization (CNV) is a major pathological process underlying retinal degenerative diseases such as wet age-related macular degeneration. While anti-VEGF therapies are widely used, limitations ...
Establishment of Immune-Evasive iPSCs from PBMCs Using B2M Knockout and CD47/HLA-E Overexpression [0.03%]
基于B2M基因敲除及CD47/HLA-E过表达的免疫逃逸性诱导多能干细胞系的建立
Cha Yeon Kim,Cholong Jeong,Yeon-Ju Jeong et al.
Cha Yeon Kim et al.
Background: Induced pluripotent stem cells (iPSCs) represent a promising source for regenerative therapies, yet allogeneic transplantation is limited by immune rejection. While strategies for generating hypoimmune iPSCs h...
circRNA_Atp8a1 Promotes Glycolytic Reprogramming in Damage of Intestinal Mucosal Barrier by Upregulating IGF2 through miR-200b-3p [0.03%]
circRNA_Atp8a1通过上调IGF2促进miR-200b-3p介导的肠黏膜屏障损伤中的糖酵解重编程
Wen Qiang Yuan,Yun Han Yang,Peng Shuang Shi et al.
Wen Qiang Yuan et al.
Background: This study investigated a circRNA (Circ_Atp8a1) in regulating intestinal epithelial repair in intestinal mucosal barrier damage. Methods: ...
Correction: Construction of Chitosan Oligosaccharide-Coated Nanostructured Lipid Carriers for the Sustained Release of Strontium Ranelate [0.03%]
关于硫酸软骨素修复兔膝关节半月板损伤的实验研究 Correction:壳聚糖寡糖包覆纳米结构脂质载体递送雷洛昔芬缓释体系的构建
Hayeon Lim,Yoseph Seo,Sung Jun Min et al.
Hayeon Lim et al.
Published Erratum
Tissue engineering and regenerative medicine. 2025 Jul 17. DOI:10.1007/s13770-025-00743-8 2025
Enhancing Long-Term Survival and Self-Renewal of Primary Hepatocytes via Rapid Spheroid Formation Using Rocker System through Co-Culturing with HUVEC Over-Expressing RSPO1 [0.03%]
通过HUVEC过表达RSPO1共培养使用Rocker系统快速形成类器官滴以增强原代肝细胞的长期存活和自我更新能力
Yuting He,Qin Liu,Yanyan Zhou et al.
Yuting He et al.
Background: Porcine primary hepatocytes are vital for liver therapy due to their procurement ease and robust functions. However, they rapidly dedifferentiate in vitro, challenging large-scale maintenance. This study aims ...
Strontium-Doped Marine Collagen Membranes Promote Osteogenesis by Inducing M2 Macrophage Polarization [0.03%]
掺锶海洋胶原膜通过诱导M2型巨噬细胞极化促进成骨作用
Hao Xu,Xin Li,Wenxue Wang et al.
Hao Xu et al.
Background: The design of bone biomaterials has shifted from promoting bone differentiation to "immune osteogenic coupling". Macrophages play a key role in immune regulation, with their polarization state critically shapi...
SIRT4 Regulated by a Mechanosensor, PIEZO1 Shows a Protective Function to Suppress Ox-LDL Uptake in Endothelial Cells [0.03%]
由机械感受器PIEZO1调控的SIRT4在抑制内皮细胞摄取氧化低密度脂蛋白中发挥保护作用
Vadym Kopych,Avelino Dos Santos Da Costa,Kwideok Park
Vadym Kopych
Background: Endothelial cells (ECs) are key regulators of vascular function, adapting to mechanical forces, such as shear stress to maintain vascular homeostasis. Disruption of this adaptation, particularly in the regions...