Comparative Transcriptomic Profiling of Mesenchymal Stem Cells from Distinct Tissue Origins and Isolation Methods Highlights the Stability and Immunomodulatory Signature of Umbilical Cord-Derived Smumf Cells [0.03%]
来自不同组织来源和分离方法的间充质干细胞转录组学特征分析突显了脐带来源的Smumfs细胞的稳定性和免疫调节信号
Min Ji Lee,Kyungtaek Park,Sungho Won et al.
Min Ji Lee et al.
Background: Mesenchymal stem cells (MSCs) derived from bone marrow (BM), adipose tissue (AD), and umbilical cord (UC) exhibit therapeutic potential in regenerative medicine. However, their properties, including transcript...
Using Low-Speed Rotation in Heparin Immobilization Improved Antithrombogenicity of Tubular Acellular Vascular Scaffolds [0.03%]
低速旋转硫酸肝素固定法可改善脱细胞血管移植物的抗凝血性能
Hoang Minh Lam,Nho Thuan Nguyen,My Thi Ngoc Nguyen et al.
Hoang Minh Lam et al.
Background: Acellular tubular artery scaffolds offer structural support for vascular regeneration but are inherently limited by poor anticoagulant properties, which increases the risk of thrombus formation following impla...
Derivation of Granulosa-Like Cells from Human Endometrial iPSCs for Autologous Estradiol Production [0.03%]
人子宫内膜诱导多能干细胞向颗粒细胞样分化用于自身雌二醇生产
Hyun Kyung Kim,Eun Jung Suh,SiHyun Cho et al.
Hyun Kyung Kim et al.
Background: Granulosa-like cells (GLCs) were differentiated from human endometrium-derived induced pluripotent stem cells (heiPSCs). This study aimed to establish a GLC differentiation protocol as a defined means to produ...
Chondrogenic Differentiation of Stem Cells for Cartilage Regeneration: Advances and Future Perspectives [0.03%]
干细胞软骨分化的进展及未来前景应用于 cartilage再生
Ahmed Abdal Dayem,Abdelbary Prince,Ahmed M M Gabr
Ahmed Abdal Dayem
Background: Cartilage has limited self-repair capacity, making it vulnerable to damage from aging, trauma, or mechanical stress, which can progress into severe joint disorders. Stem cell-based therapies offer a promising ...
A 3D Printed Poly(ε-caprolactone)-Collagen Hybrid Mesh (TissueDerm) for Breast Reconstruction after Mastectomy in a Pig Model [0.03%]
一种用于猪乳腺癌乳房切除术后重建的3D打印聚己内酯-胶原杂化网片(TissueDerm)
Kyu-Sik Shim,Han-Saem Jo,Shin Hyun Kim et al.
Kyu-Sik Shim et al.
Background: Implant supporting materials are currently used in breast reconstruction. However, when used in humans, they are associated with several problems. To address these issues, a new mesh called TissueDerm was crea...
A Novel Scaffold-Free Engineered Cartilage Using Combined Chondrocyte Pellets and Sheets in Chondrogenic Differentiation Medium [0.03%]
一种新型无支架工程软骨：联合使用软骨细胞 pellet 和 sheet 在软骨诱导分化培养基中的应用
Sopita Wongin-Sangphet,Pinprapha Sribenjarat,Pojchong Chotiyarnwong et al.
Sopita Wongin-Sangphet et al.
Background: The scaffold-free approach has emerged with a focus on creating cartilage-like tissues using cell pellets, cell spheroids, and cell sheets. However, complete repair of damaged cartilage using these tissues rem...
Mycophenolic Acid Induces Osteogenesis in Tonsil-Derived Mesenchymal Stem Cells through Inhibition of IMPDH and HDAC3 [0.03%]
霉酚酸通过抑制次黄嘌呤单核苷酸脱氢酶和组蛋白去乙酰化酶3诱导扁桃体来源的间充质干细胞成骨分化
Young Min Choi,Yeseul Jang,Saeseul Choi et al.
Young Min Choi et al.
Background: Mycophenolic acid (MPA) is a well-known inhibitor of inosine monophosphate dehydrogenases (IMPDH), and our previous study also highlighted its inhibitory effects on histone deacetylases (HDACs). This study aim...
Hyaluronic Acid-Modified N,N,N-trimethyl Chitosan-Poly (β-Aamino Ester) Nanocarriers Loaded with miR210 for Targeted Inhibition of Renal Fibrosis [0.03%]
透明质酸修饰的N，N，N-三甲基壳聚糖-聚（β-氨基酸酯）纳米载体负载miR210用于靶向抑制肾纤维化
Qin-Ke Lv,Mou-Ying Du,Ai-Mei Gong et al.
Qin-Ke Lv et al.
Background: The clinical application of miR210, which possesses the capability to effectively alleviate renal interstitial fibrosis (RIF), is greatly constrained by its poor stability and lack of targeting abilities. ...
Mulberry Silk Worm Pupae Oil and Prussian Blue Nanoparticle Enriched Multi-Faceted Polyvinyl Alcohol Nanofiber for Infectious Full Thickness Skin Wound Healing [0.03%]
含桑蚕蛹油和柏林蓝纳米粒子的多功能聚乙烯醇纳米纤维用于感染性全层皮肤伤口修复
Manish Kumar,Dilip Kumar Arya,Salem Salman Almujri et al.
Manish Kumar et al.
Background: Recently, electrospun nanofiber composite scaffolds encaged with bioactive agents have gained prominence as an innovative therapy for managing full-thickness infectious wounds. ...
Global Research Trends in EV-Based Cell-Free Therapy for Osteoarthritis: A Bibliometric Analysis [0.03%]
基于细胞外囊泡的自由疗法治疗骨关节炎的研究趋势分析—— bibliometric视角
Chuanhui Zhang,Chen Xu,Chengshuai Sun et al.
Chuanhui Zhang et al.
Background: Osteoarthritis (OA) represents a major global health challenge with no ideal treatment options available. Early-stage treatment typically focuses on symptomatic relief of pain and stiffness; while late-stage p...