Twin Glomeruli: a Newly Discovered Marker of Neonephrogenesis in the Ischemia-Reperfusion Injured Adult Mouse Kidney [0.03%]
异丙肾上腺素损伤的成年小鼠肾脏新生的双肾小球标志物发现及意义研究
Hanguk Hwang,Dongju Woo,You Ri Park et al.
Hanguk Hwang et al.
Background: The renal glomerulus, a capillary network between two arterioles, is essential for urine production in mammals. While it partially regenerates after renal injury, its precise mechanisms remain unclear, and ste...
Adipose-Derived Stem Cells in Traumatic Brain Injury: A Systematic Review of Preclinical Studies [0.03%]
脂肪源性干细胞在创伤性脑损伤中的作用：一项系统综述研究
Marcio Yuri Ferreira,Luis F Fabrini Paleare,Yasmin P Silva et al.
Marcio Yuri Ferreira et al.
Background: Although traumatic brain injury (TBI) is a significant cause of morbidity and mortality worldwide, there have been few significant therapeutic advances in recent years. Preclinical studies have explored the po...
3D Printed Patient-Specific Resorbable Bone Scaffolds for Alveolar Bone Regeneration [0.03%]
个性化3D打印可吸收骨支架用于牙槽骨再生
Puneet Wadhwa,Ho-Kyung Lim,Hyon-Seok Jang et al.
Puneet Wadhwa et al.
Background: Alveolar bone loss following trauma, periodontal disease, congenital anomalies, or tooth extraction poses a major challenge for oral rehabilitation, especially in implant dentistry. Traditional grafting techni...
Optimal IFN-γ Priming and Therapeutic Efficacy of 3D-Cultured Human Umbilical Cord-Derived Mesenchymal Stem Cells [0.03%]
三维培养的人脐带间充质干细胞的最优IFN-γ诱导和治疗效果研究
Siwoo Lee,So-Yeon Yun,Yerin Kim et al.
Siwoo Lee et al.
Background: This study focuses on addressing the challenges associated with temporomandibular joint osteoarthritis (TMJOA), a condition currently considered incurable. Osteoarthritis (OA) is a degenerative disease of cart...
Low-Intensity Electric Field Stimulation Modulates Proliferation, Stemness, and Chondrogenesis of Tonsil-Derived Mesenchymal Stem Cells [0.03%]
低强度电场刺激调节扁桃体来源的间充质干细胞增殖、干性及软骨分化的作用及机制研究
Gwangho Yoon,Ju Kwang Choi,Jee Hwan Jang et al.
Gwangho Yoon et al.
Background: Electric field (EF) stimulation is an emerging biophysical approach that enhances stem cell function by mimicking endogenous wound currents. However, its effects on tonsil-derived mesenchymal stem cells (TMSCs...
Vav1 Sustains the Expression of Insulin, PDX1 and miR-375 During Differentiation of hiPSCs to β Cells: A Potential Target to Improve the In Vitro Generation of Insulin-Producing Cells [0.03%]
Vav1促进hiPSC向β细胞分化过程中胰岛素、PDX1和miR-375的表达：一个提高体外产生胰岛素细胞潜能的新靶点
Marina Pierantoni,Valentina Zamarian,Federica Brugnoli et al.
Marina Pierantoni et al.
Backround: Human-induced pluripotent stem cells (hiPSCs) have emerged as a promising source of transplantable insulinproducing cells (IPCs) to restore insulin levels in Type 1 Diabetes (T1D) patients. Despite progress, ob...
GelMA Hydrogel/Alginate-Based Scaffolds: 3D Bioprinting for Cartilage Tissue Engineering [0.03%]
基于明胶和海藻酸盐的用于软骨组织工程的三维打印支架研究
Tae Hyung Kim,Young Sam Kim,In Kyong Shim et al.
Tae Hyung Kim et al.
Background: The perichondrium-a natural fibrous membrane encasing cartilage-plays a pivotal role in nutrient delivery and matrix regulation; however, it is often overlooked in engineered constructs. This study aimed to fa...
Engineering Mesenchymal Stem Cell-Derived Extracellular Vesicles for the Treatment of Chronic Kidney Diseases [0.03%]
工程化间充质干细胞来源的外泌体治疗慢性肾脏疾病
Hsiu-Jung Liao,Kai-Hsiang Shu,Wei-Che Yu et al.
Hsiu-Jung Liao et al.
Background: Chronic kidney disease (CKD) is a progressive disorder that leads to significant structural and functional changes in the kidneys, posing a major global health concern and contributing to high mortality rates....
Macrophage Paracrine Signalling Differentially Affects Fibroblast-Induced Collagenous Tissue Remodelling [0.03%]
巨噬细胞旁分泌信号通过不同的方式影响成纤维细胞诱导的胶原组织重塑
Hannah F M Brouwer,Amal K Mansoor,Sylvia Dekker et al.
Hannah F M Brouwer et al.
Background: Upon injury, tissue repair often leads to a loss in functionality, organisation, and structure. The immune system, particularly macrophages, is crucial during tissue healing. Macrophages polarise into pro-infl...
Fibroblast Dynamics Following Partial and Deep Burn Injury in a Reconstructed Human Skin Model [0.03%]
基于重建的人体皮肤模型的浅二度和深二度烧伤后成纤维细胞动力学变化研究
Britt van der Leeden,H Ibrahim Korkmaz,Sanne Roffel et al.
Britt van der Leeden et al.
Background: Burn injuries are characterized by extensive and prolonged inflammatory responses that impair wound healing, especially in deep burns. Understanding the post-burn fibroblast dynamics in wound healing is critic...