Human Amniotic Mesenchymal Stromal Cells Promote Bone Regeneration via Regulating Ameloblastoma-Derived-Bone Marrow Mesenchymal Cells Crosstalk and Autophagy in Ameloblastoma Microenvironment [0.03%]
人源胎盘间充质干细胞通过调节成釉细胞瘤微环境内骨髓间充质干细胞交叉信号和自噬促进成釉细胞瘤骨骼再生
Yuhuan Xiao,Xiaofeng Fu,Weina Zhou et al.
Yuhuan Xiao et al.
Background: Growing evidence validates the vital function of mesenchymal stem cells (MSCs) in tumor development. Our previous findings have illustrated the role of MSCs in the invasion and recurrence of ameloblastoma. Ste...
Transcriptomic Profiling Reveals Mechanisms of Anoikis Resistance in Spheroid-Cultured Human Umbilical Cord Mesenchymal Stem Cells [0.03%]
转录组分析揭示人脐带间充质干细胞球形培养中抗 anoikis 的机制
Yuma Iwata,Tomofumi Kodama,Takahiro Ishikawa et al.
Yuma Iwata et al.
Background: Mesenchymal stem (stromal) cells are a promising cell source for regenerative medicine, but their therapeutic efficacy is often limited by poor engraftment and survival post-transplantation. One major contribu...
Umbilical Cord Mesenchymal Stem Cells and Wnt Pathway Modulation: A Novel Therapy for Liver Cirrhosis and Steatosis [0.03%]
脐带间充质干细胞和Wnt信号通路调控：治疗肝硬化和脂肪变性的一种新疗法
Yanxuan Wen,Nouman Amjad,Omar Mukamab et al.
Yanxuan Wen et al.
Background: The Wnt signalling pathway, one of the key classical stem cell pathways, plays an important role in helping the liver regenerate after injury. Stem cells can influence changes in adult cell behaviour by either...
Polydeoxyribonucleotide (PDRN) in Dentistry: Narrative Review for Mechanisms and Emerging Clinical Applications [0.03%]
牙科中的聚脱氧核糖核酸(PDRN): 机制和新兴临床应用的叙述性综述
Jeong-Kui Ku,Pil-Young Yun,Yeong Kon Jeong
Jeong-Kui Ku
Background: Polydeoxyribonucleotide (PDRN) has emerged as a promising and cost-effective biological agent in regenerative medicine due to its anti-inflammatory, angiogenic, and tissue-regenerative properties. ...
Therapeutic Efficacy of Mesenchymal Stem Cells (MSCs) on Alzheimer's Disease: Review of Clinical Results [0.03%]
间充质干细胞(MSCs)治疗阿尔茨海默病的疗效：临床结果回顾性研究
Ae-Lee Kim,Woon Kyu Lee,Soonjo Kwon et al.
Ae-Lee Kim et al.
Background: Alzheimer's disease (AD) presents significant unmet medical needs with no effective therapeutic options. Current pharmacological treatments provide only symptomatic relief and do not prevent the ongoing neurod...
Ho Yong Kim,Sungwook Kang,Se Heang Oh
Ho Yong Kim
Background: It is well recognized that interesting biological phenomena occur in various organisms in microgravity. However, real microgravity research is limited by cost and accessibility. Furthermore, current ground-bas...
High-Concentration Type I Atelocollagen Enhances Early Cartilage Regeneration: An In Vivo Comparative Study [0.03%]
高浓度Ⅰ型胶原蛋白促进软骨早期再生：体内比较研究
Bo Seung Bae,Seon Ae Kim,Eun Jeong Go et al.
Bo Seung Bae et al.
Background: Type I atelocollagen is used to treat full-thickness chondral lesions. However, evidence on the concentration-dependent effects of atelocollagen-based scaffolds on chondrogenesis is lacking. This study aimed t...
Combining Surface Modification and Bioactive Cues to Enhance Medpor® Implant Integration In Vivo [0.03%]
结合表面修饰和生物活性信号以增强Medpor植入物的体内整合能力
Dina Gadalla,Maeve M Kennedy,Jamie E Ganem et al.
Dina Gadalla et al.
Background: Achieving stable and functional integration of synthetic implants with host tissue remains a key challenge in tissue engineering. Medpor®, a porous high-density polyethylene (HDPE) implant widely used in cran...
Bacteriophage Cocktail in Hydrogel Dressing Modulates Macrophage Responses and Induces Skin Cell Migration [0.03%]
水凝胶敷料中的噬菌体混合物可调节巨噬细胞反应并促进皮肤细胞迁移
Ming-Shun Wu,Sheng-Jie Shiue,Qiu-Yun Zheng et al.
Ming-Shun Wu et al.
Background: Bacteriophage mixtures have been explored as biomaterials to promote tissue repair. In this study, we tested the hypothesis that incorporating a phage mixture into a wound dressing could modulate immune cell r...
Recent Advances in Hydrogels as Therapeutic Tools for Spinal Cord Injury Regeneration [0.03%]
水凝胶在脊髓损伤再生治疗中的最新进展
Jiaxi Chen,Fangsu Yan,Jinyi Liu et al.
Jiaxi Chen et al.
Introduction: It is estimated that more than 27 million people worldwide suffer from spinal cord injury (SCI) due to road traffic accidents, falls, and other causes, with 1 million new cases occurring each year. The prima...