GPRC6A-Duox1 Axis Regulates the Hair Cycle Through H2O2 Generation [0.03%]
GPRC6A-Duox1轴通过生成H2O2调节毛囊生长周期
Kkotnara Park,Areum Cho,Jung Min Park et al.
Kkotnara Park et al.
Background: Emerging evidence suggests that G-protein-coupled receptor family C group 6 member A (GPRC6A) and Dual oxidase 1 (Duox1) mediate a non-classical testosterone signaling pathway. However, the molecular mechanism...
Intralesional Adipose-Derived Stem Cells Reverse Established Dermal Fibrosis and Modulate Angiogenesis-Related Readouts in a Murine Systemic Sclerosis Model [0.03%]
自体脂肪源性干细胞逆转小鼠系统性硬化模型 established 皮肤纤维化并调节与血管生成相关的分子标志物
Eunji Lee,Yeon Hee Ryu,Su Jin Lee et al.
Eunji Lee et al.
Background: Systemic sclerosis (SSc) is characterized by progressive dermal fibrosis and microvascular dysfunction, and no approved therapy reliably reverses established skin fibrosis or durably restores microvascular per...
Optimal Protocol for Differentiation of Human Tonsil-Derived Mesenchymal Stem Cells into Pancreatic β-like Cells [0.03%]
人类扁桃体来源的间充质干细胞向胰岛β样细胞分化的最佳方案
Jiin Yang,Ha Yeong Kim,So Jeong Kim et al.
Jiin Yang et al.
Background: Diabetes mellitus, characterized by β-cell dysfunction and loss, results in impaired insulin secretion and chronic metabolic complications. Mesenchymal stem cells represent a promising source for β-cell rege...
Impact of Probiotic-Adjunctive Vonoprazan-Amoxicillin Dual Therapy on Gut Microbiota and Clinical Symptoms in Helicobacter pylori Eradication [0.03%]
益生菌联合伏诺拉生-阿莫西林二联疗法对根除幽门螺杆菌的胃肠道微生态及临床症状的影响研究
YingYing Yang,ChunHui Lan,Zheng Jiang
YingYing Yang
Background: This study evaluates the impact of Bacillus subtilis dual-strain enteric-coated capsules combined with vonoprazan-amoxicillin (VA) therapy on Helicobacter pylori (Hp) eradication rates, gastrointestinal sympto...
Optimizing Cell Isolation for Adipose- and Synovium Derived Mesenchymal Stem Cells from Infrapatellar Fat Pad [0.03%]
来源于鹅足脂肪垫的间充质干细胞的细胞分离优化方法
Yeeun Kim,Hee-Woong Yun,Sujin Noh et al.
Yeeun Kim et al.
Background: The infrapatellar fat pad (IFP) is a rich source of mesenchymal stem cells (MSCs) with dual contributions from adipose and synovial tissues. The heterogeneity of IFP-derived MSCs and the lack of standardized i...
Human Amniotic Fluid Stem Cell-mediated Biomechanical Restoration of Urinary Continence in Rats [0.03%]
人羊水干细胞介导的恢复大鼠尿失禁生物力学功能的研究
Shing-Hwa Lu,Shiaw-Min Hwang,Navneet Kumar Dubey et al.
Shing-Hwa Lu et al.
Background: Stress urinary incontinence (SUI) adversely impacts millions worldwide due to weakened pelvic floor muscles and urethral sphincter dysfunction. To date, there is a lack of effective non-surgical treatment for ...
Regenerative effects of myogenic gene transfected MSC derived exosomes on radiation esophagitis [0.03%]
基因转染的间充质干细胞来源的外泌体对放射性食管炎再生修复作用的研究
Min-Kyung Kim,In Gul Kim,So Young Eom et al.
Min-Kyung Kim et al.
Background: Radiation esophagitis is a common adverse effect of radiotherapy for head and neck cancers, and is marked by irreversible damage and fibrosis of esophageal muscle tissue. Although mesenchymal stem cell (MSC) t...
Poly(2-Methacryloxyethyl Phosphorylcholine-Co-Butyl Methacrylate) Coating Enhances Biomimetic Mineralization of Bioglass and Promotes Cellular Proliferation [0.03%]
聚[2-(甲基丙烯酸氧乙基磷酰胆碱)-共-丁基丙烯酸甲酯]涂层可增强生物玻璃的仿生矿化并促进细胞增殖
Hye June Byun,Mi Yeon Ha,Gun-Jae Jeong et al.
Hye June Byun et al.
Background: Biologically active glasses (BG) are widely studied as potential materials for bone tissue engineering, owing to their capacity to form hydroxyapatite (HA) layers when exposed to body fluids. However, the deme...
Recent Progress of Dopamine-Modified Tissue Adhesives for Biomedical Applications in Underwater Environments [0.03%]
用于水下环境 biomedical 应用的多巴胺改性组织粘合剂的最新进展
Chong-Su Cho,Gi-Yeon Han,Eun Byul Koh et al.
Chong-Su Cho et al.
Background: Underwater adhesion of polymeric adhesives is highly desirable in specific applications such as wound dressings, wearable devices, bioelectronic devices, biosensors, and water pipeline leakage repairing. Howev...
Liraglutide Promoted Osteogenic Differentiation of Dental Pulp Stem Cells via H3K18 Lactylation-Dependent DSPP Activation [0.03%]
利拉鲁肽通过组蛋白H3K18乳酰化激活DSPP促进牙髓干细胞成骨分化
Ruixue Li,Jing Zhang,Xixi Song et al.
Ruixue Li et al.
Background: Dental pulp stem cells (DPSCs) are critical for periodontal tissue regeneration, yet their therapeutic potential is limited by suboptimal osteogenic differentiation. Liraglutide (LIRA), a glucagon-like peptide...