The prevalence of patients who mistakenly referred to upper respiratory tract secretions as sputum [0.03%]
上呼吸道分泌物被误称为痰的患病率
Tadao Nagasaki,Masato Muraki,Soichiro Hanada et al.
Tadao Nagasaki et al.
Background: Patients sometimes misidentify upper respiratory tract secretions or saliva as "sputum." The objective of this study was to investigate the prevalence of such misidentification and its clinical associations. ...
Effects of olfactory stimulation with L-menthol on sensations of discomfort on exertion in patients with chronic lung diseases [0.03%]
L-薄荷醇嗅觉刺激对慢性肺部疾病患者运动不适感的影响
Soh Imamura,Takeshi Inagaki,Koichiro Tatsumi et al.
Soh Imamura et al.
Background: Olfactory stimulation with L-menthol may reduce certain discomfort sensations, including dyspnea. Chronic obstructive pulmonary disease (COPD) and idiopathic interstitial pneumonias (IIPs) have distinct physio...
Clinical characteristics and systemic treatment in patients with elderly-onset sarcoidosis: A retrospective single-centre study in Japan [0.03%]
日本单中心回顾性研究中的老年期发病性狼疮病患者的临床特征及其系统治疗状况
Hitokazu Tsukao,Michiru Sawahata,Yoshitaka Yamanouchi et al.
Hitokazu Tsukao et al.
Background: The mean age at diagnosis of sarcoidosis has been increasing worldwide, yet the clinical characteristics and treatment patterns of elderly-onset cases remain insufficiently defined, particularly in Asian popul...
Extracellular DNA in bronchoalveolar lavage fluid as a candidate biomarker of disease severity in autoimmune pulmonary alveolar proteinosis [0.03%]
支气管肺泡灌洗液中的细胞外DNA可作为自身免疫性肺泡蛋白沉积症病情严重程度的候选生物标志物
Toshiki Kimura,Kosuke Imamura,Chieko Yoshida et al.
Toshiki Kimura et al.
Background: Autoimmune pulmonary alveolar proteinosis (aPAP) results from the neutralization of autoantibodies against granulocyte-macrophage colony-stimulating factor, which leads to alveolar macrophage (AM) dysfunction ...
Post-bronchoscopy sputum culture improves detection of nontuberculous mycobacterial pulmonary disease: A retrospective Study [0.03%]
支气管镜检查后痰培养可提高对非结核分枝杆菌肺病的检出率：一项回顾性研究
Kohei Yamamoto,Tatsuya Imabayashi,Toshiyuki Tanaka et al.
Kohei Yamamoto et al.
Background: In the diagnosis of Mycobacterium tuberculosis, collecting post-bronchoscopy sputum (PBS), as recommended by major guidelines, enhances the microbiological yield; however, evidence for PBS in nontuberculous my...
Handgrip strength in Japanese patients with chronic obstructive pulmonary disease: a prospective cohort study [0.03%]
日本慢性阻塞性肺疾病患者的手握力：前瞻性队列研究
Seiichi Kobayashi,Manabu Ono,Masatsugu Ishida et al.
Seiichi Kobayashi et al.
Background: Skeletal muscle dysfunction frequently accompanies chronic obstructive pulmonary disease (COPD). Handgrip strength (HGS) is a simple, reliable measure of muscle strength. This study aimed to evaluate its progn...
Diverse histopathological patterns in Fleischner-defined interstitial lung abnormalities: Radiologic-Pathologic correlation and reclassification using 2025 American Thoracic Society statement [0.03%]
Fleischner学会定义的间质性肺异常的多种组织病理学模式：使用美国胸科协会2025年声明进行影像学-病理学相关性和再分类的多样化.histopathological patterns
Taiki Fukuda,Kaori Ishida,Tomonori Tanaka et al.
Taiki Fukuda et al.
Background: Interstitial lung abnormalities (ILA) are CT-detected interstitial abnormalities that may represent early-stage interstitial lung disease (ILD). However, histopathologic correlations remain limited, with previ...
Clinical characteristics and severity of primary ciliary dyskinesia caused by large homozygous deletion including exons 1-4 of DRC1: A multicenter retrospective cohort study [0.03%]
DRC1外显子1-4大片段纯合缺失所致原发纤毛运动障碍的临床特征和严重程度：多中心回顾性队列研究
Masashi Ito,Atsuko Nakano,Yukiko Arimoto et al.
Masashi Ito et al.
Background: Approximately half of primary ciliary dyskinesia (PCD) patients in Japan carry a large homozygous deletion encompassing exons 1-4 of DRC1 gene. However, the clinical manifestations of PCD patients with DRC1 va...
A case of synchronous multiple primary lung cancers each harboring an EGFR mutation or an ALK fusion gene alone that responded to osimertinib with chemotherapy [0.03%]
一例伴有EGFR突变或ALK融合基因之一的同步多原发肺癌对奥希替尼联合化疗有效的病例报告
Doppo Fukui,Daisuke Morinaga,Jun Sakakibara-Konishi et al.
Doppo Fukui et al.
A comprehensive pathological evaluation is useful for diagnosing synchronous multiple primary lung cancer (sMPLC). However, a consensus regarding treatment for sMPLC with different driver mutations is lacking. We present a case of sMPLC har...
Performance validation of a closed loop fully automated AI model for lung nodule stratification in screening cases [0.03%]
基于筛查病例的肺结节分层闭环全自动AI模型性能验证
A Taha,M S Muneer,A Kalra et al.
A Taha et al.
Background: Several limitations hinder the effectiveness of human-based lung cancer screening (LCS): high false-positive rates leading to unnecessary follow-up imaging, procedures, and surgeries; inter-reader variability;...