Clinical characteristics of autoantibodies neutralizing type I interferons in patients with coronavirus disease 2019 across phases of severe acute respiratory syndrome coronavirus 2 circulation [0.03%]
抗I型干扰素自身抗体阳性的新型冠状病毒肺炎患者的临床特征贯穿于SARS-CoV-2流行各阶段
Haruka Sofuku,Ami Aoki,Natsumi Sakai et al.
Haruka Sofuku et al.
Background: Autoantibodies neutralizing type I interferons (AAN-I-IFNs) have been identified as major risk factors for life-threatening coronavirus disease 2019 (COVID-19), particularly during the early phase of severe ac...
Comorbidity of autoimmune diseases in patients with autoimmune pulmonary alveolar proteinosis [0.03%]
伴有自身免疫性肺泡蛋白沉积症的自身免疫性疾病共病情况研究
Eisuke Fujishiro,Takuma Katano,Masaya Fukami et al.
Eisuke Fujishiro et al.
Background: Autoimmune diseases coexisting with autoimmune pulmonary alveolar proteinosis (APAP) are rare. Therefore, the clinical characteristics of complications of these diseases are not well known. ...
Efficacy and safety of nintedanib for older adults with idiopathic pulmonary fibrosis or progressive fibrosing interstitial lung disease: A multicenter retrospective study in Japan [0.03%]
尼达尼布治疗日本特发性肺纤维化或进行性纤维化间质性肺病患者的疗效和安全性：一项多中心回顾性研究
Shiho Goda,Tadaaki Yamada,Yasuhiro Goto et al.
Shiho Goda et al.
Background: Nintedanib is widely used for idiopathic pulmonary fibrosis (IPF) and progressive fibrosing interstitial lung disease (PF-ILD). However, real-world data regarding its efficacy and safety in patients aged 75 ye...
Toward refining hemoptysis severity classification using acute-phase CT findings [0.03%]
基于急性期CT表现的咯血严重程度分类的优化研究
Hideo Ishikawa,Takashi Nishihara
Hideo Ishikawa
Clinical outcome following benralizumab discontinuation in patients with severe eosinophilic asthma: A single-center study [0.03%]
重症嗜酸性粒细胞性哮喘患者停用本纳利珠单抗后的临床结局：一项单中心研究
Satoshi Hamada,Eriko Ogino,Hirotaka Yasuba
Satoshi Hamada
Currently, no clear guidance exists regarding the optimal duration of biologic therapy in asthma. This study retrospectively examined clinical outcomes following benralizumab discontinuation in patients with severe eosinophilic asthma. Nine...
Epidemiology and clinical characteristics of primary ciliary dyskinesia in Japan: A nationwide database analysis [0.03%]
日本原发纤毛运动障碍的流行病学和临床特征：全国数据库分析结果
Koichi Miyashita,Hironao Hozumi,Tomoyuki Fujisawa et al.
Koichi Miyashita et al.
Background: Primary ciliary dyskinesia (PCD) is a rare genetic disorder characterized by impaired mucociliary clearance causing chronic respiratory infections and progressive lung disease. Despite its clinical significanc...
Masato Tashiro,Tomoyuki Shirahige,Takahiro Takazono et al.
Masato Tashiro et al.
Azole-resistant Aspergillus, particularly azole-resistant Aspergillus fumigatus (ARAf), is an increasingly consequential problem in Japan because triazoles remain central to aspergillosis management and chronic pulmonary aspergillosis (CPA)...
Decline in physical function and baseline depressive symptoms are associated with worsening asthma outcomes in older adults: A 12-month prospective cohort study [0.03%]
身体功能下降和基线抑郁症状与老年人哮喘恶化的相关性：一项为期12个月的前瞻性队列研究
Akiko Maeda,Kazunori Tobino,Norihiro Harada et al.
Akiko Maeda et al.
Background: Comprehensive geriatric assessment (CGA) may identify non-pulmonary vulnerabilities that influence asthma outcomes in older adults; however, longitudinal associations with clinical outcomes remain unclear. We ...
Clinical features of macrolide-resistant Mycoplasma pneumoniae pneumonia: Can the JRS pneumonia guidelines be applied? [0.03%]
宏环素耐药肺炎支原体肺炎的临床特点分析：JRS指南是否适用？
Naoyuki Miyashita,Makoto Ogata,Naoki Fukuda et al.
Naoyuki Miyashita et al.
Background: The JRS pneumonia guidelines 2024 created and recommend a predictive score for clinical diagnosis of Mycoplasma pneumoniae pneumonia. However, there are no data examining its usefulness in macrolide-resistant ...
Clinical significance of 18F-FDG uptake in interstitial lung lesions in lung cancer patients with interstitial lung disease treated with immune checkpoint inhibitor therapy [0.03%]
免疫检查点抑制剂治疗合并间质性肺病的肺癌患者中間質性肺 lesion 的 18F-FDG 吸收的意义
Tsuguhiro Furukawa,Kimitaka Akaike,Koichi Saruwatari et al.
Tsuguhiro Furukawa et al.
Background: Patients with lung cancer (LC) complicated by interstitial lung disease (ILD) exhibit an increased incidence of immune-related adverse event associated pneumonitis (irAEp), precipitating severe respiratory com...