Clinical relevance of extrapulmonary chest computed tomography findings in COPD and asthma: A narrative review of established evidence in COPD and emerging insights in asthma [0.03%]
慢性阻塞性肺疾病和哮喘患者胸部CT影像的临床意义：慢阻肺已有证据及哮喘新兴观点的文字叙述性回顾
Naoya Tanabe,Shotaro Chubachi
Naoya Tanabe
Chronic obstructive pulmonary disease (COPD) and asthma pose health and socioeconomic challenges worldwide. While management strategies mainly target airway and parenchymal pathology, extrapulmonary abnormalities also influence clinical out...
Inflammation-induced cysts mimic honeycombing on high-resolution computed tomography in rheumatoid arthritis-associated usual interstitial pneumonia [0.03%]
炎症诱发的囊肿可模仿高分辨率CT下的蜂窝肺改变-类风湿关节炎相关的 UIP病例报告
Yasuhiko Yamano,Hitoshi Tokuda,Tamiko Takemura et al.
Yasuhiko Yamano et al.
Background: Rheumatoid arthritis-associated interstitial lung disease (RA-ILD) often manifests with a usual interstitial pneumonia (UIP) pattern and has a poor prognosis similar to idiopathic pulmonary fibrosis (IPF). Des...
Nontuberculous mycobacterial pulmonary disease: Epidemiology, prognostic determinants, and implications for treatment decision [0.03%]
非结核分枝杆菌肺病的流行病学、预后因素及其对治疗决策的影响
Kazuaki Takeda,Takahiro Takazono,Hiroshi Mukae
Kazuaki Takeda
The global burden of nontuberculous mycobacterial pulmonary disease (NTM-PD) continues to increase, particularly in East Asia, including Japan. Although epidemiological understanding has expanded, the clinical course of NTM-PD remains highl...
The therapeutic dilemma triangle in rheumatoid arthritis-related respiratory disease [0.03%]
类风湿关节炎相关呼吸疾病的治疗困境三角
Hideaki Yamakawa
Hideaki Yamakawa
Rheumatoid arthritis (RA) is increasingly well controlled with conventional disease-modifying antirheumatic drugs (DMARDs) including methotrexate, as well as the widespread use of biologic agents and Janus kinase (JAK) inhibitors, which hav...
Pulmonary fibrosis with a rare SFTPC variant (c.304G>A, p.Val102Met): A case report [0.03%]
携带罕见SFTPC变异体(c.304G>A,p.Val102Met)的肺纤维化一例报告
Hirokazu Yura,Takashi Kido,Noriho Sakamoto et al.
Hirokazu Yura et al.
Genetically associated pulmonary fibrosis often occurs at a younger age, progresses rapidly, and has poor prognosis; however, its diagnosis and management remain challenging. Causative gene mutations are classified into two main categories:...
Clinical evidence on BCG vaccination and COVID-19 infection: A systematic review [0.03%]
结核菌素(BCG)疫苗与新冠肺炎感染关系的临床证据：系统综述
Praneta Yadav,Arpita Singh,Manju Kumari et al.
Praneta Yadav et al.
The COVID-19 pandemic, starting in late 2019, led to the rapid development of SARS-CoV-2 vaccines, though early availability was limited, and variants like Delta and Omicron impacted their effectiveness. The Bacillus Calmette-Guérin (BCG) ...
Genetic susceptibility, terminal bronchiole pathology, and inflammation: An integrated mechanisms of the pathogenic process in chronic obstructive pulmonary disease [0.03%]
遗传易感性、终末呼吸性细支气管病理性变化和炎症：慢性阻塞性肺疾病的发病机制整合模型
Naoya Fujino,Takuya Saito,Mitsuhiro Yamada et al.
Naoya Fujino et al.
Chronic obstructive pulmonary disease (COPD) remains a leading cause of mortality yet understanding of disease initiation and progression is incomplete. Current therapeutic agents provide symptomatic relief but fail to halt disease progress...
Pneumonitis risk from pembrolizumab in non-small cell lung cancer: Interstitial abnormalities matter, and so does treatment [0.03%]
派姆单抗治疗非小细胞肺癌肺炎风险：间质异常和治疗均有关
Hideaki Yamakawa,Daisuke Nakatani,Rie Kawabe et al.
Hideaki Yamakawa et al.
Background: Immune checkpoint inhibitors (ICIs) such as pembrolizumab have improved outcomes in non-small cell lung cancer (NSCLC), but immune-related pneumonitis remains a clinically important concern. While interstitial...
Possible impact of sputum viscoelastic changes and airway fungal colonization on asthma exacerbation: Observations from 7 patients with severe asthma receiving biologics [0.03%]
痰粘弹性改变和气道真菌定植对生物制剂治疗重度哮喘患者急性加重的影响：7例患者的观察指标变化
Haruhiko Ogawa,Yuka Uchida
Haruhiko Ogawa
We report a case series of 7 patients with severe asthma who initiated biologic therapy due to frequent exacerbations. Sputum viscoelasticity was measured using a benchtop rheometer (Rheomuco®). After initiation of biologic therapy, sputum...
Survival of patients with newly diagnosed IPF at the time of respiratory-related hospitalization [0.03%]
新诊断的IPF患者在呼吸系统相关住院时的生存率
Ryo Yamazaki,Osamu Nishiyama,Yoshiyuki Kawabata et al.
Ryo Yamazaki et al.
Background: Some patients are newly diagnosed with idiopathic pulmonary fibrosis (IPF) in acute condition at the time of a respiratory-related hospitalization (RH). However, among patients with IPF, these patients have ne...