Preparation and Optimization of Fast Dissolving Film of Naratr iptan Hydrochloride [0.03%]
纳拉曲坦氢溴酸盐快速溶出膜的制备及优化
Koradia D Krishna,Sidhdhapara T Pradip,Sheth R Navin
Koradia D Krishna
Background: Naratriptan is second-generation triptan class of antimigraine drug which selectively bind with 5-HT(1B/1D) receptor. It is widely used to treat the migraine attack due to its better tolerability and lower rec...
Development and Characterization Pulsatile Microspheres of Nifedipine for Hypertension [0.03%]
用于治疗高血压的硝苯地平脉冲微球的开发与表征
Rahul Taneja,Ghanshyam D Gupta
Rahul Taneja
Background: To develop pulsatile microspheres of Nifedipine blend of polymers Carbopol 971P and Eudragit RS100 for antihypertensive to release the drug at a particular lag time. ...
Acyclovir Solid Lipid Nanoparticles for Skin Drug Delivery: Fabrication, Characterization and In vitro Study [0.03%]
用于皮肤药物递送的阿昔洛韦固脂纳米粒：制备、表征及体外研究
Kaur Bhupinder,Maria J Newton
Kaur Bhupinder
Objective: The fractionated coconut oil based Solid Lipid Nanoparticles (SLNs) of Acyclovir (ACV) were fabricated in two batches by using Glyceryl mono stearate (GMS) and Lipoid S75 (Fat free soybean phospholipids with 70...
Formulation Development and Evaluation of Lyophilized Nasal Inserts for Migraine Treatment [0.03%]
一种用于治疗偏头痛的冷冻干燥鼻内制剂的开发与评估
Sarode D Harshada,Atishkumar S Mundada
Sarode D Harshada
Background: Nasal inserts are novel, solid, bioadhesive dosage forms administered via nasal route for prolonged systemic drug delivery. The principle of the dosage form is that, after administration nasal inserts imbibe n...
Formulation and Optimization of Lansoprazole Pellets Using Factorial Design Prepared by Extrusion-Spheronization Technique Using Carboxymethyl Tamarind Kernel Powder [0.03%]
卡波姆丙烯酸树脂复合凝胶层控释包衣雷贝拉唑钠素丸的制备及其体外释放度的影响因素考察
Sagar Sopanrao Muley,Tanaji Nandgude,Sushilkumar Poddar
Sagar Sopanrao Muley
Background: In the present study, Lansoprazole pellets were prepared employing a novel excipient Carboxymethyl tamarind kernel powder (CMTKP) using extrusion-spheronization technique. Various research studies including pa...
Development and Evaluation of Naproxen Sodium Gel Using Piper cubeba for Enhanced Transdermal Drug Delivery and Therapeutic Facilitation [0.03%]
使用胡椒虎眼草开发和评估那洛普森钠凝胶以增强经皮药物递送和治疗促进的疗效研究
Sunetra Patwardhan,Manohar Patil,Anbazhagan Sockalingam
Sunetra Patwardhan
Background: The absorption of drug through skin avoids many side effects of oral route like gastric irritation, nausea, systemic toxicity etc and thus improves patient compliance. Naproxen sodium (NPRS) is one of the pote...
Anti-Psychotic Activity of Aqueous Root Extract of Hemidesmus indicus: A Time Bound Study in Rats [0.03%]
印度地续根水提取物抗精神病作用的时间限制研究 rats 中的研究
Ashwathanarayana Madhu,Gaurav Gupta,Bharati Arali et al.
Ashwathanarayana Madhu et al.
Aims and background: Psychosis is a neurological disorder, which is usually defined as the "loss of contact with reality." As medicine 'Hemidesmusindicus' holds a reputed place in all systems of medicine in India. It is g...
Addressing the Challenge of Developing a Physiologically Relevant Dissolution Test for Regulatory Purposes [0.03%]
开发用于监管目的的生理相关溶出度测试的挑战及应对措施
Vivian Gray
Vivian Gray
The challenge of developing a physiologically relevant dissolution test to satisfy regulatory agencies has pushed drug manufacturers to engage in "design of experiment" method development, which helps manufacturers address variability, diss...
Multi-particulate Systems: Cutting-edge Technology for Controlled Drug Delivery [0.03%]
多单元传递系统：控制药物释放的前沿技术
Sarika Wairkar,Ram Gaud,Adhithi Raghavan
Sarika Wairkar
Background: In the last two decades, multi-particulate dosage forms have caught the attention of formulation scientists due to their tremendous potential as a drug delivery system with a broad range of applications. ...
Development of Self Emulsifying Formulations of Poorly Soluble Naproxen for Enhanced Drug Delivery [0.03%]
开发难溶性萘普生自乳化药物传递体系的优化研究
Subhash C B Penjuri,Damineni Saritha,Nagaraju Ravouru et al.
Subhash C B Penjuri et al.
Background: The objective of this investigation was to develop a self emulsifying drug delivery system (SEDDS) of naproxen, a poorly water soluble drug, which could improve its solubility and oral bioavailability. ...