Zeenat Iqbal,Fahima Dilnawaz
Zeenat Iqbal
Background: Vaginal drug delivery approach represents one of the imperative strategies for local and systemic delivery of drugs. The peculiar dense vascular networks, mucus permeability, and range of physiological charact...
A Review on Enteric Coated Pellets Composed of Core Pellets Prepared by Extrusion-Spheronization [0.03%]
采用挤出圆整法制备素芯的肠溶微丸制剂研究进展
Hetal Patel,Mukesh Gohel
Hetal Patel
Enteric coated dosage form bypasses the stomach and releases the drug into the small intestine. Advantages of enteric coated pellets in comparison with enteric coated tablets are a) Pellets provide rapid onset of action and faster drug rele...
Design, Development and In vitro/Ex vivo Evaluation of Mucoadhesive Buccal Film of Benzydamine Hydrochloride for the Effective Treatment of Aphthous Stomatitis [0.03%]
设计、开发和体外/ ex vivo评估苯扎明盐酸盐粘膜颊部薄膜以有效治疗口疮性口炎
Deepak Sharma,Amit Sharma,Rajeev Garg
Deepak Sharma
Background: During the recent two decades, the development of mucoadhesive drug delivery system has been gained tremendous importance to cure many recurrent diseases of the oral cavity. The drug delivery through the bucca...
Nazlı Erdoğar,Safiye Akkın,Erem Bilensoy
Nazlı Erdoğar
Background: For the past few decades, there has been considerable research interest in drug delivery strategies using nanoparticulate systems as carriers for a wide range of active pharmaceutical ingredients. ...
Jing Wang,Guqi Wang,Hannah Wang et al.
Jing Wang et al.
Skeletal muscle is a highly-specialized tissue that is capable of contractile function and able to withstand and adapt to daily mechanical and physiological stress. Musculoskeletal disorders, including muscular dystrophies, result in chroni...
Montelukast Sodium Formulation Containing Green Tea Extract to Reduce the Oxidative Stress in Guinea Pig Model of Chronic Allergic Asthma [0.03%]
含有绿茶提取物的孟鲁司特钠递送体系对慢性过敏性哮喘模型氧化应激的影响研究
Neelam Singh,Giriraj T Kulkarni,Yatendra Kumar
Neelam Singh
Aim and background: The rationale of this study is that, treatment of asthmatic Guinea pig with combined administration of Montelukast sodium and Green Tea Extract (GTE) as a single capsule will mitigate the inflammatory ...
Mesoporous Silica Nanoparticles: A Versatile Platform for Biomedical Applications [0.03%]
介孔二氧化硅纳米颗粒：一种多功能的生物医药应用平台
Pooja Jain,Nazia Hassan,Zeenat Iqbal et al.
Pooja Jain et al.
Background: Nanotechnology-based drug delivery approach has emerged as a promising field, where different kinds of formulations are developed for therapeutic applications. Inflowing of nanomedicine developed through vario...
Simpal Kumari,Vipan Kumar Kamboj,Diksha Rajpoot et al.
Simpal Kumari et al.
Gold nanoparticles possess unique mechanical, chemical, photo-optical and biological properties and have been an interesting field of research on life sciences. The research studies produced new nanodevices and nanotechnology-based biosensi...
Self-Emulsifying Drug Delivery System of Simvastatin: Formulation Development, Optimization by Box- Behnken Design, In-Vitro and In-Situ Single-Pass Intestinal Perfusion (SPIP) Studies [0.03%]
辛伐他丁自乳化药物传递系统的设计开发、箱-贝恩肯设计优化以及体外和在体单向肠道灌流研究
Madhu Verma,Arun Nanda,Yatendra Kumar
Madhu Verma
Purpose: The purpose of the study was formulation development, optimization and evaluation of a Self-Emulsifying Drug Delivery System (SEDDS) of Simvastatin (SIM) for improvement in dissolution and bioavailability of SIM....
Role of Porous Carriers in the Biopharmaceutical Performance of Solid SMEDDS of Canagliflozin [0.03%]
多孔载体在固体SMEDDS中卡格列净生物药剂学性能中的作用机制研究
Dilpreet Singh,Ashok K Tiwary,Neena Bedi
Dilpreet Singh
Objective: The aim of the present investigation entails the development of solid SMEDDS for improving the oral bioavailability of canagliflozin using porous carriers. The previous patent (WO2017046730A1) was based on enha...