Recent Patents on Solid Dispersions Emphasize Promising Benefits in Solubility Enhancement of Poorly Water-soluble Drugs [0.03%]
近期固体分散体的相关专利强调了其在改善难溶性药物溶解性方面的潜在优势
Manisha Saini,Shailender Bhatt,Harish Dureja et al.
Manisha Saini et al.
Background: In the development of drug delivery systems, drugs' solubility remains the most challenging constraint. Many newly synthesized chemical compounds are available, but they involve low solubility and poor permeab...
Emerging Treatment Options of Pluronic in Designing Colloidal Nano and Microcarriers Carriers for Various Therapies [0.03%]
Pluronic在设计用于各种疗法的胶体纳米和微载体中的新兴治疗选项
Pooja Mathur,Ravinder Verma,Laxmi Rani et al.
Pooja Mathur et al.
Poloxamers, commonly known as Pluronics, are a special family of synthetic tri-block copolymers with a core structure made of hydrophobic poly (propylene oxide) chains sandwiched by two hydrophilic poly (ethylene oxide) chains. It is possib...
Imaging and Non-imaging Analytical Techniques Used for Drug Nanosizing and their Patents: An Overview [0.03%]
药物纳米化所用的 imaging 和 non-imaging 分析技术及其专利：综述
Vijay Agarwal,Meenakshi Bajpai
Vijay Agarwal
Background: Nanosizing is widely recognized as an effective technique for improving the solubility, dissolution rate, onset of action, and bioavailability of poorly water-soluble drugs. To control the execution and behavi...
An Efficient Suppression of EGFR and B-Raf mRNA Overexpression in the Lung of Benzo[a]pyrene-induced mice by Cationic Lipo-ATRA Nanoformulation [0.03%]
阳离子脂质ATRA纳米制剂有效抑制苯并[a]芘诱导小鼠肺组织中EGFR和B-Raf的过度表达
Berlin Grace Viswanathan Mariammal,David Wilson Devarajan,Siddikuzzaman et al.
Berlin Grace Viswanathan Mariammal et al.
Background: The molecular drug all-trans retinoic acid (ATRA) acts on cancer cells via different molecular pathways, but its poor bioavailability in cancer cells limits its potency. This study was, therefore, carried out ...
Ritu Karwasra,Shivkant Sharma,Isha Sharma et al.
Ritu Karwasra et al.
The convergence of diabetology and nanotechnology has emerged as a promising synergy with the potential to revolutionize the management and treatment of diabetes mellitus. Diabetes, a complex metabolic disorder affecting millions worldwide,...
Applications of Nanomedicine in Brain Tumor Therapy: Nanocarrierbased Drug Delivery Platforms, CChallenges, and Perspectives [0.03%]
纳米医学在脑肿瘤治疗中的应用：纳米载体药物递送平台、挑战及前景分析
Ravinder Verma,Lakshita Rao,Harish Kumar et al.
Ravinder Verma et al.
Background: The most difficult kind of cancer to treat is brain cancer, which causes around 3% of all cancer-related deaths. The targeted delivery is improved with the use of technologies based on nanotechnology that are ...
Piyali Barik,Pooja Rani Bhaisal,Sonia Singh
Piyali Barik
In recent years, nanotechnology has been the focus of study for the cure of different diseases, among which nanosponge delivery system is one of a kind. Nano sponges are tiny, highly porous, three-dimensional nanostructures with a size rang...
Exploring the Prospective of Curcumin-loaded Nanomedicine in Brain Cancer Therapy: An Overview of Recent Updates and Patented Nanoformulations [0.03%]
姜黄素载药纳米医学在脑癌治疗中的前景探索：近期进展和专利纳米制剂概述
Ravinder Verma,Lakshita Rao,Diksha Nagpal et al.
Ravinder Verma et al.
Cancer is a complex, one of the fatal non-communicable diseases, and its treatment has enormous challenges, with variable efficacy of traditional anti-cancer agents. By 2025, it is expected that 420 million additional cases of cancer will b...
Shubhrat Maheshwari,Aditya Singh
Shubhrat Maheshwari
Cells and nervous system connections that are crucial for movement, coordination, strength, sensation, and thought are gradually damaged in neurodegenerative illnesses. Amyloid beta (Aβ)- accumulating macromolecules in the brain are the pr...
Nano - Based Therapeutic Strategies in Management of Rheumatoid Arthritis [0.03%]
基于纳米技术的治疗策略在类风湿性关节炎管理中的应用
Gunjan Nautiyal,Shiv Kant Sharma,Dhirender Kaushik et al.
Gunjan Nautiyal et al.
Background: Rheumatoid arthritis (RA) is a chronic autoimmune disease, progressively distinctive via cartilage destruction, auto-antibody production, severe joint pain, and synovial inflammation. Nanotechnology represents...