Edward E Walsh,Ann R Falsey
Edward E Walsh
Respiratory Syncytial Virus, generally recognized for its role as the major respiratory pathogen in newborn infants and young children, is also a significant pathogen in adults. It is a frequent cause of upper and lower respiratory illness ...
The non-structural proteins of RSV: targeting interferon antagonists for vaccine development [0.03%]
RSV非结构蛋白：针对干扰素拮抗剂的疫苗研发
Michael N Teng
Michael N Teng
Over fifty years have passed since the identification of respiratory syncytial virus (RSV) as an important pediatric pathogen. However, an effective vaccine is still lacking. Immunization with formalin-inactivated RSV resulted in vaccine-en...
Caroline Breese Hall
Caroline Breese Hall
Respiratory syncytial virus (RSV) was first isolated from infants by Chanock and colleagues in 1957. However, control of this ubiquitous agent has yet to be achieved. RSV is recognized as the primary cause of hospitalization for acute lower...
Protein-protein interactions in RSV assembly: potential targets for attenuating RSV strains [0.03%]
RSV装配中的蛋白质-蛋白质相互作用：削弱RSV毒株的潜在靶点
Reena Ghildyal,David A Jans,Philip G Bardin et al.
Reena Ghildyal et al.
Respiratory syncytial virus (RSV) is the major respiratory pathogen of infants and children worldwide, with no effective treatment or vaccine available. Steady progress has been made in understanding the respiratory syncytial virus lifecycl...
Heather M Costello,William C Ray,Supranee Chaiwatpongsakorn et al.
Heather M Costello et al.
Respiratory syncytial virus (RSV) is the most significant cause of pediatric respiratory infections. Palivizumab (Synagis®), a humanized monoclonal antibody, has been used successfully for a number of years to prevent severe RSV disease in...
Reena Ghildyal,John Mills
Reena Ghildyal
Vaccines for cytomegalovirus [0.03%]
巨细胞病毒的疫苗
D I Bernstein
D I Bernstein
Cytomegalovirus (CMV) is a leading cause of congenital infection worldwide and therefore is recognized as an important target for vaccine development. Data from natural infections and work done with animal models, including models of congen...
Vaccines for cytomegalovirus [0.03%]
巨细胞病毒的疫苗
D I Bernstein
D I Bernstein
Cytomegalovirus (CMV) is a leading cause of congenital infection worldwide and therefore is recognized as an important target for vaccine development. Data from natural infections and work done with animal models, including models of congen...
Antiretroviral therapy does not block the secretion of the human immunodeficiency virus tat protein [0.03%]
抗逆转录病毒治疗不能阻止人类免疫缺陷病毒tat蛋白的分泌
Sonia Mediouni,Albert Darque,Gilbert Baillat et al.
Sonia Mediouni et al.
Tat is a viral protein secreted from HIV infected cells and extra cellular Tat is suspected to prevent destruction of HIV infected cells from cells of the cellular immunity. The effect of anti retroviral therapy (ART) on Tat secretion has n...
Dominic J Glover
Dominic J Glover
Improved understanding of the signals that direct the intracellular transport of endogenous mammalian proteins, as well as the means by which viral invaders hijack transport pathways during infection, has revealed a plethora of methods for ...