Emergence of oseltamivir resistance: control and management of influenza before, during and after the pandemic [0.03%]
奥司他韦耐药性的出现：大流行前、期间和之后的流感控制与管理
Rashmi Dixit,Gulam Khandaker,Scott Ilgoutz et al.
Rashmi Dixit et al.
Neuraminidase inhibitors (NAIs), such as oseltamivir and zanamivir, are the medicines of choice against influenza A or B. Oseltamivir resistance can be conferred by a single point missense mutation from histidine to tyrosine at position 275...
Towards a personalised approach to managing influenza infections in infants and children - food for thought and a note on oseltamivir [0.03%]
关于婴幼儿流感感染的个性化处理方法的思考及奥司他韦点评
Barbara Rath,Franziska Tief,Katharina Karsch et al.
Barbara Rath et al.
Acute respiratory infections represent common diseases in childhood and a challenge to infection control, public heath, and the clinical management of patients and their families. Children are avid spreaders of respiratory viruses, and seas...
Oseltamivir in neonates, infants and young children: a focus on clinical pharmacology [0.03%]
奥司他韦在新生儿、婴儿和幼儿中的应用：临床药理学方面不容忽视
Eda Karadag-Oncel,Mehmet Ceyhan
Eda Karadag-Oncel
Influenza is a cause of significant morbidity and mortality in young children. It is associated with high annual attack rates as well as being responsible for frequent outpatient visits and hospitalisations. Children aged
Pharmacokinetics and pharmacodynamics of oseltamivir in neonates, infants and children [0.03%]
奥司他韦在新生儿、婴儿和儿童中的药代动力学和药效学研究
Joseph F Standing,Maria Tsolia,Irja Lutsar
Joseph F Standing
Pharmacokinetic-pharmacodynamic (PKPD) studies have the potential to yield useful information on whether and how a drug works, and what dose to use. This approach is often best suited to situations where dose-response relationships need to ...
Mohamed A Kamal
Mohamed A Kamal
Oseltamivir is listed by the World Health Organization as an essential drug for the treatment and prophylaxis of both seasonal and pandemic influenza. Since influenza mortality is highest in neonates and infants, optimal dosing of oseltamiv...
Harunor Rashid,Leon Heron
Harunor Rashid
Nicholas Chim,Cedric P. Owens,Heidi Contreras et al.
Nicholas Chim et al.
Withdrawn by the publisher.
Nutritional antioxidants and their applications in cardiometabolic diseases [0.03%]
营养抗氧化剂及其在心血管代谢性疾病中的应用研究进展
Mena Soory
Mena Soory
There is an increasing global trend in cardiometabolic disorders being a leading cause of morbidity and mortality. Adverse dietary habits and sedentary lifestyles contribute to cardiovascular disease (CVD) and diabetes mellitus (DM). Dietar...
Lessons from Anaplasma phagocytophilum: chromatin remodeling by bacterial effectors [0.03%]
阿纳普lasma phagocytophilum的启示：细菌效应子介导的染色质重塑
Kristen E Rennoll-Bankert,J Stephen Dumler
Kristen E Rennoll-Bankert
Bacterial pathogens can alter global host gene expression via histone modifications and chromatin remodeling in order to subvert host responses, including those involved with innate immunity, allowing for bacterial survival. Shigella flexne...
Venkataramanujam Srinivasan,Mahaneem Mohamed,Rahimah Zakaria et al.
Venkataramanujam Srinivasan et al.
Malaria, one of the most deadly diseases of our time affects more than 200 million people across the globe and is responsible for about one million deaths annually. Until recently Plasmodium falciparum has been the main cause for malarial i...