Qi Zhao,Erin Weber,Haitao Yang
Qi Zhao
The recent, fatal outbreak of the novel coronavirus strain in the Middle East highlights the real threat posed by this unique virus family. Neither pharmaceutical cures nor preventive vaccines are clinically available to fight against coron...
Qi Zhao,Erin Weber,Haitao Yang
Qi Zhao
The recent, fatal outbreak of the novel coronavirus strain in the Middle East highlights the real threat posed by this unique virus family. Neither pharmaceutical cures nor preventive vaccines are clinically available to fight against coron...
Hanumantharao Paritala,Kate S Carroll
Hanumantharao Paritala
The identification of new antibacterial targets is urgently needed to address multidrug resistant and latent tuberculosis infection. Sulfur metabolic pathways are essential for survival and the expression of virulence in many pathogenic bac...
Mass spectrometry characterization of trypanothione and novel peptides of medical importance isolated from Acanthamoeba polyphaga [0.03%]
从Acanthamoeba polyphaga中分离得到新型医学重要化合物的串联质谱表征研究—— trypanothione及其他肽类成分
Raul N Ondarza,Eva Hernandez,Gerardo Hurtado et al.
Raul N Ondarza et al.
This paper presents unequivocal results about the presence of trypanothione and its precursor glutathionespermidine from the opportunistic human pathogen Acanthamoeba polyphaga. They were isolated by RP-HPLC as thiolbimane derivatives and c...
Proresolution mediators and receptors: novel drug targets for enhancing pharmacological armamentarium against periodontal inflammation [0.03%]
促Resolution介质和受体：增强牙周炎药物武器库中的新药靶点
Vishakha Grover,Ranjan Malhotra,Anoop Kapoor et al.
Vishakha Grover et al.
Periodontal diseases are comprised of a group of inflammatory conditions that result in the destruction of the supporting structures of the dentition. Emphasis has traditionally been placed on the deleterious actions of lipid mediators, suc...
Plant-based hydrocarbon esters from Tragia involucrata possess antimicrobial and anti-inflammatory activities [0.03%]
基底植物Tragia involucrata中的碳氢化合物酯具有抗菌和抗炎活性
Ramar Perumal Samy,Gautam Sethi,Vincent T K Chow et al.
Ramar Perumal Samy et al.
Antimicrobial and anti-inflammatory activities of hydrocarbon esters obtained from Tragia involucrata were evaluated by disk-diffusion (250 µg/ml), and broth-dilution (500-7.8 µg/ml), methods against bacteria. Among the compounds, shellso...
Jaana Suvisaari,Outi Mantere
Jaana Suvisaari
Recent research suggests that inflammation and immunity may have a role in the etiology of psychotic disorders. There is evidence of proinflammatory activation of the innate immune system and an activation of the T-cells of the adaptive imm...
Post marketing surveillance on safety and efficacy of IMOD in Iranian patients with HIV/AIDS [0.03%]
伊朗HIV/AIDS患者使用IMOD的上市后监测研究安全性及有效性
Minoo Mohraz,Abbas Sedaghat,SeyedAhmad SeyedAlinaghi et al.
Minoo Mohraz et al.
Acquired immune deficiency syndrome is one of the world's serious health problems. Immune-based therapy is a new approach in the treatment of HIV infected patients. IMOD™ with the ability to correct immune deficiencies has been introduced ...
Oseltamivir use in adolescents and adults: clinical and economic considerations [0.03%]
青少年及成人使用奥司他韦的临床和经济因素考量
J Kevin Yin,Leon Heron,Glenn Salkeld et al.
J Kevin Yin et al.
Influenza remains an important cause of morbidity and mortality, and incurs substantial economic costs (mainly due to hospitalisation) especially for the elderly aged 65 years or more, and among those with high-risk medical conditions. Infl...
Mohamed Tashani,Harunor Rashid,Iman Ridda et al.
Mohamed Tashani et al.
The use of oseltamivir at mass gatherings (MGs) or other crowded settings has not previously been systematically examined to synthesise the evidence of its usefulness. Here we have evaluated its effectiveness by reviewing the published lite...