Design of RNA Polymerase Inhibitors as Therapeutics for Tuberculous Meningitis [0.03%]
RNA聚合酶抑制剂的设计及其在结核性脑膜炎治疗中的应用
Varalakshmi Vummidi,Sekhar Talluri
Varalakshmi Vummidi
Background: Tuberculosis is an infectious disease caused by Mycobacterium tuber-culosis. The current treatment protocols for pulmonary tuberculosis are quite effective, even though the treatment requires 3-6 months. The c...
Characterization of Antibiotic Actinomycin D Isolated from Streptomyces parvulus Collected from Marine Sponge of Barrang Lompo Island, Makassar, Indonesia [0.03%]
采自印度尼西亚巴朗咯木坡岛海洋海绵的链霉菌中分离得到活性抗肿瘤抗生素actinomycin D的结构鉴定
Herlina Rante,Gemini Alam,Yosi Bayu Murti et al.
Herlina Rante et al.
Background: Microorganisms associated with sea sponges have proven to be good natural product resources that are biologically active and pharmaceutically important. ...
A Review on the Epidemiology and Clinical Management of Neglected Tropical Diseases [0.03%]
被忽视的热带病的流行病学和临床管理综述
Medha Dwivedi,Aiswarya Pawar,Mahima Kori et al.
Medha Dwivedi et al.
Infectious disorders known as Neglected Tropical Diseases (NTDs) initially affect the world's underprivileged citizens. They have been disregarded for many years, first as a result of a general indifference to such a developing world and, m...
Drug Discovery and Exploration of Heterocycles for the Development of Anti-HIV Agents [0.03%]
用于开发抗艾滋病药物的药物发现和杂环研究
Mayura A Kale,Mamata V Jain
Mayura A Kale
It is a known fact that HIV infection remains a serious public health problem throughout the world, and the need to constantly develop new antiretroviral drugs to combat HIV emerges from the fact that repetitive mutations occurring in viral...
A Review of the Difficulties Faced by Low and Middle-income Countries in Hygiene and Healthcare Practices [0.03%]
低收入和中等收入国家在卫生保健实践中面临困难的回顾性分析
Jashan Girdhar,Kapil Shandilya,Munnawar Husaain et al.
Jashan Girdhar et al.
Hygiene has been identified as an important step in anticipating health-related pol-lution, with conflicting reports about consistent sanitation standards in the nation. This narrative review of published studies has led to the discussion o...
The Human Monkeypox Virus and Host Immunity: Emerging Diagnostic and Therapeutic Challenges [0.03%]
人猴痘病毒与宿主免疫：新兴的诊断和治疗挑战
Vijay Singh,Shailendra Dwivedi,Ruchika Agrawal et al.
Vijay Singh et al.
This article explores the Human Monkeypox Virus (MPV), a contagious virus that causes disease in both vertebrates and insects. It originated in Denmark in 1958 and expanded beyond Africa during the 1970s. The virus was initially detected in...
Screening and Identification of Natural Compounds as Potential Inhibitors of Glutamate Racemase, an Emerging Drug Target of Food Pathogen E. coli O157:H7: An In-silico Approach to Combat Increasing Drug Resistance [0.03%]
筛选和鉴定作为潜在抑制剂的天然化合物以对抗新兴药物靶点E.coli O157:H7的麸胺酸 racemase：一种应对日益严重的抗生素抗药性的计算方法
Rajnish Kumar,Samarth Gupta,Sujata Adhana et al.
Rajnish Kumar et al.
Background: Shiga Toxin-Producing Escherichia coli (E. coli O157:H7), capable of causing serious food-borne illnesses, is extensively studied and is known to be transmitted through animal reservoirs or person-to-person co...
Shivang Saxena,Shubhi Saxena,Nihar Ranjan Sahoo et al.
Shivang Saxena et al.
Echoes of the Black Death: Yersinia Pestis Resurgence and Public Health Perspectives [0.03%]
黑死病的回响：耶尔森菌再次流行及其公共卫生学视角分析
Anish Soni,Prabhjot Kaur,Naresh Kumar Rangra
Anish Soni
A Comparison of Antibiotics' Resistance Patterns of E. coli and B. Subtilis in their Biofilms and Planktonic Forms [0.03%]
生物被膜和浮游培养的大肠杆菌及枯草芽孢杆菌的抗生素抗性模式比较分析研究
Shagun Sharma,Vandana Jhalora,Shubhita Mathur et al.
Shagun Sharma et al.
Background: A biofilm refers to a community of microbial cells that adhere to surfaces that are surrounded by an extracellular polymeric substance. Bacteria employ various defence mechanisms, including biofilm formation, ...