S A Ross,Z Novak,S Pati et al.
S A Ross et al.
Cytomegalovirus (CMV) is recognized as the most common congenital viral infection in humans and an important cause of morbidity and mortality in immunocompromised hosts. This recognition of the clinical importance of invasive CMV disease in...
Amina Ahmed
Amina Ahmed
Cytomegalovirus (CMV) is an opportunistic pathogen associated with significant morbidity and mortality in immunocompromised hosts. Antiviral agents specifically targeting CMV were initially developed during the human immunodeficiency virus ...
The genetic basis of human cytomegalovirus resistance and current trends in antiviral resistance analysis [0.03%]
人类巨细胞病毒抗性的作用基因及当前抗病毒抵抗分析趋势
S H James,M N Prichard
S H James
Infections due to resistant human cytomegalovirus (CMV) are an emerging problem, particularly in immunocompromised hosts. When managing such patients, clinicians should be aware of the possibility of developing CMV antiviral resistance, esp...
Saad Nseir,Alain Durocher
Saad Nseir
Usefulness of real-time PCR for the diagnosis of sepsis in ICU-acquired infections [0.03%]
实时PCR在ICU获得性感染性脓毒症诊断中的应用价值研究
Frédéric Wallet,Caroline Loïez,Stéphanie Herwegh et al.
Frédéric Wallet et al.
Real-time PCR methods are able to rapidly detect a wide panel of microorganisms. These methods are of interest in critically ill patients to determine the presence of bacteria in the blood and other biological samples, especially in those p...
Comparative Study
Infectious disorders drug targets. 2011 Aug;11(4):348-53. DOI:10.2174/187152611796504845 2011
Cytomegalovirus infections in non-immunocompromised and immunocompromised patients in the intensive care unit [0.03%]
重症监护病房中免疫功能正常和免疫功能低下患者的巨细胞病毒感染
Diana F Florescu,Andre C Kalil
Diana F Florescu
Infection, inflammatory response, activation of coagulation cascade and sepsis are tightly interconnected. In the initial phase, sepsis is characterized by a pro-inflammatory state, while in the late phase, by an anti-inflammatory state whi...
Caroline Blazejewski,Mary-Jane Guerry,Sébastien Preau et al.
Caroline Blazejewski et al.
Hospital-acquired infections (HAI) represent the most common adverse event in the intensive care unit (ICU). Their prevalence is high and they are associated with increased morbidity and mortality. The environment plays a central role in th...
Giulia De Angelis,Giovanni Restuccia,Roberto Cauda et al.
Giulia De Angelis et al.
The role of antibiotic pressure in the selection of antibiotic-resistant bacteria is still under debate in the scientific community and often confounded by scarce data on antibiotic usage. Several studies demonstrated that prior antibiotic ...
Thomas Baudry,Florence Ader
Thomas Baudry
Several forms of supportive techniques for respiration in intensive care units (ICU) are currently available. The most widely used is invasive mechanical ventilation through the use of an endotracheal tube (ETT). ETTs are proved to be impor...
Damien Roux,Jean-Damien Ricard
Damien Roux
P. aeruginosa is the bacteria most commonly responsible for hospital-acquired and ventilator-associated pneumonia. Numerous factors are encoded in its genome, and they explain its high virulence. P. aeruginosa also develops a quorum sensing...