Tzu-Chun Chen,Shin-Ru Shih
Tzu-Chun Chen
Enteroviruses (EVs) are common and significant human pathogens in Asia. EV infections can cause a wide spectrum of acute diseases, including CNS complications. These EV infection-related CNS syndromes include acute flaccid paralysis, asepti...
Human rabies encephalitis prevention and treatment: progress since Pasteur's discovery [0.03%]
人用狂犬病脑炎预防和治疗的进展——自巴斯德发现以来的成就回顾
Laurent Dacheux,Olivier Delmas,Hervé Bourhy
Laurent Dacheux
Rabies remains one of the most ancient and deadly of human infectious diseases. This viral zoonosis is transmitted principally by the saliva of infected dogs, inducing a form of encephalomyelitis that is almost invariably fatal. Since the f...
Kallol Dutta,Arshed Nazmi,Anirban Basu
Kallol Dutta
Chemotherapy in Japanese encephalitis (JE) is at present entirely supportive and not targeted at the virus. There are no available drugs to effectively counter the viral infection, thereby making the fight against JE a daunting task. With a...
Withdrawn by the publisher.
Kenneth Mutton,Malcolm Guiver
Kenneth Mutton
Encephalitis is an inflammatory process involving the parenchyma of the brain. It typically presents as a clinical syndrome characterised by fever, headache and altered conscious level, often with focal neurological deficits and fits. The c...
Frederic Vigant,Benhur Lee
Frederic Vigant
The Paramyxoviridae family comprises of several genera that contain emerging or re-emerging threats for human and animal health with no real specific effective treatment available. Hendra and Nipah virus are members of a newly identified ge...
Chromium-picolinate therapy in diabetes care: molecular and subcellular profiling revealed a necessity for individual outcome prediction, personalised treatment algorithms and new guidelines [0.03%]
糖尿病护理中 Chromium-picolinate疗法：分子和亚细胞分析揭示了预测个体结果、个性化治疗算法和新指南的必要性
Kristina Yeghiazaryan,Viktoriya Peeva,Aparna Shenoy et al.
Kristina Yeghiazaryan et al.
Aims: Global figures clearly demonstrate inadequacy of current diabetes care: every 10 seconds one patient dies of diabetes-related pathologies. Nephropathy is the leading secondary complication of the disease. Nutritiona...
Quinoxaline 1,4-di-N-oxide and the potential for treating tuberculosis [0.03%]
喹诺酮并-dioxine-1,4-di-N-氧化物及治疗结核病的潜力
Esther Vicente,Raquel Villar,Silvia Pérez-Silanes et al.
Esther Vicente et al.
New drugs active against drug-resistant tuberculosis are urgently needed to extend the range of TB treatment options to cover drug resistant infections. Quinoxaline derivatives show very interesting biological properties (antibacterial, ant...
Targeting bacterial RNA polymerase: promises for future antisense antibiotics development [0.03%]
靶向细菌RNA聚合酶：未来反义抗生素研发的前景
Hui Bai,Ying Zhou,Zheng Hou et al.
Hui Bai et al.
The progress of transcription is synthesized by complex molecules, among which DNA-dependent RNA polymerase (RNAP) is the central enzyme. The prokaryotic RNAP is a large protein composed of core subunits (α2, β and β') and a σ factor th...
Targeting tuberculosis and HIV/AIDS: a global progress report of a deadly partnership [0.03%]
瞄准结核病和艾滋病：致命伙伴关系的全球进展报告
Jean B Nachega,Bernd Rosenkranz
Jean B Nachega