Georgios Papazisis,Spyridon Siafis
Georgios Papazisis
Background: Antipsychotic drugs are the cornerstone of schizophrenia treatment and are also indicated for other psychotic and mood disorders. Different antipsychotic drugs and their formulations are available, though liqu...
Efficacy of Zofenopril Alone or in Combination with Hydrochlorothiazide in Patients with Kidney Dysfunction [0.03%]
肾功能不全患者使用佐芬普利或佐芬普利联合氢氯噻嗪的疗效分析
Stefano Omboni,Claudio Borghi
Stefano Omboni
Hypertension and kidney disease often coexist, further increasing the risk of future cardiovascular events. Treatment of hypertensive adults with an angiotensin converting enzyme inhibitor in case of concomitant kidney disease may slow dise...
Metformin as a Radiation Modifier; Implications to Normal Tissue Protection and Tumor Sensitization [0.03%]
二甲双胍作为放射增敏剂的潜力及其对正常组织保护和肿瘤增敏的影响
Keywan Mortezaee,Dheyauldeen Shabeeb,Ahmed E Musa et al.
Keywan Mortezaee et al.
Background: Nowadays, ionizing radiation is used for several applications in medicine, industry, agriculture, and nuclear power generation. Besides the beneficial roles of ionizing radiation, there are some concerns about...
Biosimilars: An Approach to some Current Worldwide Regulation Frameworks [0.03%]
仿制生物药：目前部分世界范围监管框架的方法论思考
Efraín Esteban,Rosa-Helena Bustos,Julio-César García et al.
Efraín Esteban et al.
Developing new biologics has led to regulations and norms aimed at guaranteeing their safety, quality and effectiveness, in terms of marketing, prescription, use, interchangeability and switching. Biologics are of great importance in treati...
A Critique of Computer Simulation Software's Used in Pharmacokinetics and Pharmacodynamics Analysis [0.03%]
药代动力学和药效学分析中计算机模拟软件的批评
Vivek Dave,Renu Bala Yadav,Sachdev Yadav et al.
Vivek Dave et al.
Background: In the pharmaceutical sectors, the computer plays a crucial role as a commander of all the theoretical aspects and provides a workbench to improve the overall quality of pharmaceutical research and development...
Anaemogenic, Obesogenic and Thermogenic Potentials of Graded Doses of Monosodium Glutamate Sub-acutely Fed to Experimental Wistar Rats [0.03%]
分级剂量的单钠谷氨酸对实验大鼠的致贫血、致肥胖和产热潜力的亚急性影响研究
Salisu Nusaiba,Sulaiman Aliyu Fatima,Garba Hussaini et al.
Salisu Nusaiba et al.
Background: Monosodium Glutamate (MSG) is one of the most commonly used food additives for the enhancement of food taste and flavour. There are several conflicting reports of toxicity or otherwise safety of the compound, ...
Role of Nrf2/HO-1 and PI3K/Akt Genes in the Hepatoprotective Effect of Cilostazol [0.03%]
西洛他唑保肝作用中Nrf2/HO-1和PI3K/Akt基因的作用机制研究
Marwa Hassan,Mohamad A Ibrahim,Heba M Hafez et al.
Marwa Hassan et al.
Background: Cilostazol, a phosphodiesterase 3 inhibitor (PDE3I), is a platelet aggregation inhibitor and vasodilator that is useful for treating intermittent claudication. Experimental studies have shown that cilostazol h...
Preface: Vitamin D and QT Interval in Epilepsy: More than an Association? [0.03%]
前言：维生素D与癫痫患者的QT间期：不仅仅是关联？
Arduino A Mangoni,Elzbieta A Jarmuzewska
Arduino A Mangoni
Lipid-based siRNA Nanodelivery Systems: A Learning Process for Improving Transfer from Concepts to Clinical Applications [0.03%]
基于脂质的siRNA纳米传递系统：从概念到临床应用的学习过程
Sebastián Ezequiel Pérez,Adriana Mónica Carlucci
Sebastián Ezequiel Pérez
Background: The molecular mechanism of silencing genes using small interference RNA is as particular and innovative phenomenon as the proposed delivery systems to release them. Recent advances in RNAi have resulted in the...
Interventions for Improving Bone Mineral Density and Reducing Fracture Risk in Osteogenesis Imperfecta: A Mixed Treatment Comparison Network Meta-analysis of Randomized Controlled Clinical Trials [0.03%]
骨质疏松症患者改善骨矿物质密度和降低骨折风险的干预措施：随机对照临床试验的混合处理比较网络meta分析
Kannan Sridharan,Gowri Sivaramakrishnan
Kannan Sridharan
Background: Osteogenesis imperfecta is a rare metabolic disorder associated with reduced mineralization of bone and corresponds to increased fracture risk. We carried out the present network meta-analysis comparing all th...