Surotomycin (A Novel Cyclic Lipopeptide) vs. Vancomycin for the Treatment of Clostridioides difficile Infection: A Systematic Review and Meta-analysis [0.03%]
苏特霉素（一种新型环状脂肽）与万古霉素治疗艰难梭菌感染的系统评价和Meta分析
Aziz Muhammad,Desai Madhav,Fatima Rawish et al.
Aziz Muhammad et al.
Background: Current guidelines recommend the use of vancomycin for the initial treatment of moderate to severe Clostridioides difficile Infection (CDI). Surotomycin, a novel antibiotic, has been utilized for the managemen...
Comparison of Fentanyl, Remifentanil, Sufentanil and Alfentanil in Combination with Propofol for General Anesthesia: A Systematic Review and Meta-analysis of Randomized Controlled Trials [0.03%]
一项系统评价和 meta 分析：与丙泊酚复合使用的四种芬太尼类阿片药（氟芬那君、瑞芬太尼、舒芬太尼及 Alfentanil）用于全身麻醉的比较：随机对照试验
Kannan Sridharan,Gowri Sivaramakrishnan
Kannan Sridharan
Background: Opioid analgesics are commonly used along with propofol during general anesthesia. Due to the dearth of data on the quality of anesthesia achieved with this combination, the present meta-analysis was carried o...
Investigation of the Roles of New Antiepileptic Drugs and Serum BDNF Levels in Efficacy and Safety Monitoring and Quality of Life: A Clinical Research [0.03%]
新型抗癫痫药物及血清脑源性神经营养因子在疗效与安全性监测和生活质量评价中的作用研究：临床研究报道
Meral Demir,Emel O Akarsu,Hava O Dede et al.
Meral Demir et al.
Objective: We aimed to determine the therapeutic drug monitoring (TDM) features and the relation to Brain-Derived Neurotrophic Factor (BDNF) of frequently used new antiepileptic drugs (NADs) including lamotrigine (LTG), o...
Randomized Controlled Trial
Current clinical pharmacology. 2020;15(1):49-63. DOI:10.2174/1574884714666190312145409 2020
A Comprehensive Review on the Screening Models for the Pharmacological Assessment of Antiulcer Drugs [0.03%]
抗溃疡药物药理评价筛选模型的研究进展与展望
Abhinav P Mishra,Ankit Bajpai,Suresh Chandra
Abhinav P Mishra
Background: Due to inappropriate diet, smoking, alcohol consumption, regular use of drugs like NSAIDs and sedentary lifestyle, one may feel upper abdominal pain which may be the predictor of the gastrointestinal disorder ...
Ehsan T Moghadam,Ali Tafazoli
Ehsan T Moghadam
Background: Azithromycin is one of the most popular antibiotics in current clinical practice. This medication generally considered to be safe and well-tolerated in different demographic populations. Like any other drug, a...
Minocycline Increases in-vitro Cortical Neuronal Cell Survival after Laser Induced Axotomy [0.03%]
米诺环素能增加激光损伤轴索后培养皮层神经元的细胞存活率
Burak Yulug,Mehmet Ozansoy,Merve Alokten et al.
Burak Yulug et al.
Background: Antibiotic therapies targeting multiple regenerative mechanisms have the potential for neuroprotective effects, but the diversity of experimental strategies and analyses of non-standardised therapeutic trials ...
Comparative Study
Current clinical pharmacology. 2020;15(2):105-109. DOI:10.2174/1574884714666190226093119 2020
Impact of Ondansetron on Withdrawal Signs, Fentanyl Requirement and Pain Relief in Opioid-addicted Patients under General Anesthesia [0.03%]
盐酸昂丹司琼对全麻下吗啡依赖患者戒断症状、术后镇痛药需求及镇痛效果的影响
Farzaneh Mahikhan,Morteza Hashemian,Tania Dehesh et al.
Farzaneh Mahikhan et al.
Background: Serotonin 5-HT3 receptor antagonists such as ondansetron have been investigated to attenuate opioid withdrawal signs in studies. Objective: ...
Randomized Controlled Trial
Current clinical pharmacology. 2019;14(3):232-241. DOI:10.2174/1574884714666190131122846 2019
Mark R Jones,Ivan Urits,John Wolf et al.
Mark R Jones et al.
Background: Peripheral neuropathy is a painful condition deriving from many and varied etiologies. Certain medications have been implicated in the iatrogenic development of Drug Induced Peripheral Neuropathy (DIPN) and in...
The Effect of Methylphenidate on Reed Scaling in Benzodiazepine Poisoning: A Prospective Trial [0.03%]
甲基苯丙胺对苯二氮卓类中毒患者牙龈上皮剥脱影响的前瞻性研究
Masoud Latifi-Pour,Hossein Hassanian-Moghaddam,Helya-Sadat Mortazavi et al.
Masoud Latifi-Pour et al.
Background: Benzodiazepine is one of the most important causes of substance abuse and intoxication throughout the world and Iran. Objective: ...
Randomized Controlled Trial
Current clinical pharmacology. 2020;15(1):81-88. DOI:10.2174/1574884714666190112153157 2020
Efficacy and Safety of Nilutamide in Patients with Metastatic Prostate Cancer who Underwent Orchiectomy: A Systematic Review and Metaanalysis [0.03%]
尼鲁苔胺治疗行睾丸切除术的转移性前列腺癌患者的疗效和安全性系统评价和 meta 分析
Muhammed Rashid,K Shamshavali,Manik Chhabra
Muhammed Rashid
Background: Prostate cancer is the sixth leading cause of death, among all cancer deaths By 2030, this burden is expected to increase with 1.7 million new cases and 499,000 new deaths. We aimed to evaluate the efficacy an...