Nifedipine blocks ondansetron electrophysiological effects in rabbit purkinje fibers and decreases early after depolarization incidence [0.03%]
硝苯地平阻断昂丹司琼对兔浦肯野纤维电生理效应并降低早期后除极发生率
Rene Rouet,Morel Elvis Worou,Paolo Emilio Puddu et al.
Rene Rouet et al.
We hypothesized that a high concentration of nifedipine (1 μM), known to inhibit at least 75%of L-type Ca++ current, might counteract proarrhythmic dose-dependent effects of ondansetron (0.1 to 10 μM) in rabbit Purkinje fibers. Ondansetro...
Comparative Study
Current clinical pharmacology. 2012 Feb 1;7(1):41-8. DOI:10.2174/157488412799218789 2012
Nifedipine blocks ondansetron electrophysiological effects in rabbit purkinje fibers and decreases early after depolarization incidence [0.03%]
硝苯地平阻断昂丹司琼对兔浦肯野纤维电生理作用并减少早期后除极发生率
Rene Rouet,Morel Elvis Worou,Paolo Emilio Puddu et al.
Rene Rouet et al.
We hypothesized that a high concentration of nifedipine (1 μM), known to inhibit at least 75%of L-type Ca++ current, might counteract proarrhythmic dose-dependent effects of ondansetron (0.1 to 10 μM) in rabbit Purkinje fibers. Ondansetro...
Comparative Study
Current clinical pharmacology. 2012 Feb 1;7(1):41-8. DOI:10.2174/157488412799218789 2012
Confounding issues in estimation of patient-specific pharmacokinetic parameters and dosage individualization of aminoglycosides [0.03%]
氨基糖苷类抗生素患者特异性药动学参数估计及个体化剂量调整中的混杂问题
Reza Mehvar
Reza Mehvar
Aminoglycoside antibiotics are usually administered by multiple short intravenous infusions at fixed intervals. Today, equations reported 35 years ago by Sawchuk and Zaske are still the cornerstone of methods used for determination of patie...
Confounding issues in estimation of patient-specific pharmacokinetic parameters and dosage individualization of aminoglycosides [0.03%]
氨基糖苷类药物患者特异性药动学参数估计及剂量个体化中的混杂问题
Reza Mehvar
Reza Mehvar
Aminoglycoside antibiotics are usually administered by multiple short intravenous infusions at fixed intervals. Today, equations reported 35 years ago by Sawchuk and Zaske are still the cornerstone of methods used for determination of patie...
Frederic Hasdenteufel,Samuel Luyasu,Nicolas Hougardy et al.
Frederic Hasdenteufel et al.
Structure-activity relationships (SARs) refer to the relation between chemical structure and pharmacologic activity for a series of compounds. Since the pioneering work of Crum-Brown and Fraser in 1868, they have been increasingly used in t...
Frederic Hasdenteufel,Samuel Luyasu,Nicolas Hougardy et al.
Frederic Hasdenteufel et al.
Structure-activity relationships (SARs) refer to the relation between chemical structure and pharmacologic activity for a series of compounds. Since the pioneering work of Crum-Brown and Fraser in 1868, they have been increasingly used in t...
Quality assessment of clinical practice guidelines for the prescription of antidepressant drugs during pregnancy [0.03%]
评估产科抗抑郁药处方的临床实践指南的质量
Fabiano Santos,Ivan Sola,David Rigau et al.
Fabiano Santos et al.
Antidepressant use during the gestational period remains a controversial issue. The objective of this study was to appraise the quality of the available clinical practice guidelines (CPGs) that includes recommendations for antidepressant us...
Quality assessment of clinical practice guidelines for the prescription of antidepressant drugs during pregnancy [0.03%]
评估孕期抗抑郁药处方的临床实践指南的质量
Fabiano Santos,Ivan Sola,David Rigau et al.
Fabiano Santos et al.
Antidepressant use during the gestational period remains a controversial issue. The objective of this study was to appraise the quality of the available clinical practice guidelines (CPGs) that includes recommendations for antidepressant us...
Deepti Chopra,Bharti Bhandari,Neeta Wardhan
Deepti Chopra
Ciclesonide (CIC) is a novel inhaled corticosteroid (ICS) approved by US Food and Drug Administration for the treatment of persistent asthma, available as a pressurized metered-dose inhaler in two strengths, 80 mcg/activation and 160 mcg/ac...
Deepti Chopra,Bharti Bhandari,Neeta Wardhan
Deepti Chopra
Ciclesonide (CIC) is a novel inhaled corticosteroid (ICS) approved by US Food and Drug Administration for the treatment of persistent asthma, available as a pressurized metered-dose inhaler in two strengths, 80 mcg/activation and 160 mcg/ac...