Awareness and Perception of Thromboembolism and Thromboprophylaxis among Hospitalized Patients in Jordan [0.03%]
关于血栓栓塞和血栓预防的知识和认知在约旦住院患者中的调查研究
Anan S Jarab,Sayer Al-Azzam,Rawan Badaineh et al.
Anan S Jarab et al.
Background and objective: Despite the established importance of thromboprophylaxis in patients with Venous Thromboembolism (VTE), a limited number of studies have assessed the awareness of VTE and thromboprophylaxis thera...
The New Immunotherapy Combinations in the Treatment of Advanced Non-Small Cell Lung Cancer: Reality and Perspectives [0.03%]
免疫疗法在晚期非小细胞肺癌治疗中的新联合应用：现状与未来展望
Danilo Rocco,Luigi D Gravara,Cesare Gridelli
Danilo Rocco
Background: In the recent years, immunotherapeutics and specifically immunecheckpoints inhibitors have marked a significant shift in the diagnostic and therapeutic algorithm of Non-Small Cell Lung Cancer (NSCLC), allowing...
Massumeh Niazi,Nasrin Galehdar,Mohammad Jamshidi et al.
Massumeh Niazi et al.
Background: Heart failure is a common medical problem in the world, which has a high prevalence in both developed and developing countries. Today, among the medications used for the heart failure treatment, there are many...
Cadazolid vs Vancomycin for the Treatment of Clostridioides difficile Infection: Systematic Review with Meta-analysis [0.03%]
Cadazolid与万古霉素治疗艰难梭菌感染的系统评价和 meta 分析
Aziz Muhammad,Weissman Simcha,Fatima Rawish et al.
Aziz Muhammad et al.
Background: Current guidelines recommend the use of vancomycin for the initial treatment of Clostridioides difficile Infection (CDI). Cadazolid, an experimental drug, has been utilized and compared in several studies with...
Oral and Intra-nasal Administration of Nanoparticles in the Cerebral Ischemia Treatment in Animal Experiments: Considering its Advantages and Disadvantages [0.03%]
动物实验中纳米颗粒口服和鼻内给药用于脑缺血治疗的利弊探讨
Firoozeh Alavian,Nasrin Shams
Firoozeh Alavian
Background: Over the past few decades, nanotechnology has dramatically advanced; from the precise strategies of synthesizing modern nanostructures to methods of entry into the body. Using nanotechnology in diagnosis, drug...
Comparison of the Mean Minimum Dose of Bolus Oxytocin for Proper Uterine Contraction during Cesarean Section [0.03%]
剖宫产术中适度子宫收缩的单次缩宫素剂量的比较研究
Siavash Beiranvand,Arash Karimi,Sepideh Vahabi et al.
Siavash Beiranvand et al.
Background: Cesarean section is the most common midwifery operation. The aim of this study is to determine the mean minimum dose of bolus oxytocin for proper uterine contraction during cesarean section. ...
Comparative Study
Current clinical pharmacology. 2019;14(3):208-213. DOI:10.2174/1574884714666190524100214 2019
Melatonin Modulates Regulation of NOX2 and NOX4 Following Irradiation in the Lung [0.03%]
褪黑激素调节放射后的NOX2和NOX4调控
Masoud Najafi,Alireza Shirazi,Elahe Motevaseli et al.
Masoud Najafi et al.
Background: Exposure to ionizing radiation may lead to chronic upregulation of inflammatory mediators and pro-oxidant enzymes, which give rise to continuous production of reactive oxygen species (ROS). NADPH oxidases are ...
Medication Management Issues in Old Age: A Call for Submissions to Current Clinical Pharmacology [0.03%]
老年患者的用药问题：征集当前临床药理学投稿通知
Arduino A Mangoni,Kimberley Bryant,Elzbieta A Jarmuzewska
Arduino A Mangoni
Concomitant Use of Cotrimoxazole and Atazanavir in HIV-infected Patients: A Therapeutic Drug Monitoring and Pharmacovigilance Based Dual Approach [0.03%]
曲霉属感染患者的康替唑和阿扎那韦合并使用：基于治疗药物监测和药物警戒的双重方法
Miantezila B Joe,Landman Roland,Chouchana Laurent et al.
Miantezila B Joe et al.
Background: Cotrimoxazole is the main antibiotic used in primary prophylaxis for opportunistic infections in advanced HIV infection. This drug can inhibit one of the metabolic pathways of atazanavir (ATV), such as the cyt...
Science-based Ethnic Bridging in Drug Development; Review of Recent Precedence and Suggested Steps Forward [0.03%]
基于科学的民族融合在药物开发中的作用；近期先例回顾及未来建议步骤
Ewoud-Jan van Hoogdalem,John P Jones Iii,John Constant et al.
Ewoud-Jan van Hoogdalem et al.
Background: Exposure, safety and/or efficacy of drugs are subject to potential differences between human races or ethnicities, as acknowledged by regulatory guidance and by label texts of various, but not all approved dru...