Pharmacological Interactions of Paraoxonase 1 (PON1): A HDL-Bound Antiatherogenic Enzyme [0.03%]
关于高密度脂蛋白结合的抗动脉粥样生成酶-卵磷脂胆固醇酰基转移酶的药理学相互作用(PON1)
Abdolkarim Mahrooz
Abdolkarim Mahrooz
A growing interest exists in documenting the role of paraoxonase 1 (PON1) in different human diseases including, cardiovascular disease, obesity, diabetes mellitus, cancers, aging, and several neurological disorders. Three aspects of PON1 h...
The Therapeutic Role of Lamotrigine And Topiramate In A Depressive Patient With Anxiety Symptoms And Cognitive Decline: Neurometabolic Correlates [0.03%]
拉莫三嗪和托吡酯在抑郁、焦虑和认知功能下降患者中的疗效：神经代谢研究指标相关的治疗作用
Lutfu Hanoglu,Burak Yulug,Tansel Cakir et al.
Lutfu Hanoglu et al.
We describe here 67 years old women presented with symptoms of anxiety and cognitive impairment that responded well to the combined treatment of lamotrigine and topiramate. In contrast to recent data, we have shown that lamotrigine and topi...
In Vivo Measurement in Pigs of Wash-In Kinetics of Xenon at its Site of Action [0.03%]
猪体内测量氙气在作用位点的洗入动力学
Gebhard Froeba,Oliver Adolph
Gebhard Froeba
Background: Xenon (Xe) in many respects is an ideal anaesthetic agent. Its blood/gas partition coefficient is lower than that of any other anaesthetic, enabling rapid induction of and emergence from anaesthesia. While the...
Ethosomes as Vesicles for Effective Transdermal Delivery: From Bench to Clinical Implementation [0.03%]
用于有效透皮给药的脂质体 vesicle：从实验室到临床应用
Nida Akhtar,Anurag Varma,Kamla Pathak
Nida Akhtar
Background: Drug delivery across the deeper layers of skin to make it systemically available is a considerable challenge in the development of a carrier. Numerous efforts have been put forward to find ways to overcome the...
Klára Krempaská,Ladislav Vaško,Janka Vašková
Klára Krempaská
Background: The toxicity of lead and its compounds is well known, causing anemia by inhibiting the synthesis of porphyrins. The neurotoxic effects, particularly in the young, alter the structure of cell membranes and DNA....
Pramipexole Responsive Neck Numbness: The Therapeutic Role of Dopamine Agonists in the Spinal Cord Indicating to a Common Spinal Pathophysiology with Restless Leg Syndrome (RLS)? [0.03%]
普拉克索治疗颈麻木：多巴胺激动剂在脊髓中的治疗作用与不安腿综合征(RLS)的共同脊髓病理生理学指示？
Burak Yulug,Lütfü Hanoglu
Burak Yulug
Background: There is still speculative data regarding the role of spinal dopaminergic neurotransmission in restless leg syndrome (RLS). Methods: ...
Preoperative Plasma Aldosterone Levels and Postoperative Atrial Fibrillation Occurrence Following Cardiac Surgery: A Review of Literature and Design of the ALDO-POAF Study (ALDOsterone for Prediction of Post-Operative Atrial Fibrillation) [0.03%]
术前血浆醛固酮水平与心脏手术后房颤发生的相关性：文献回顾及ALDO-POAF研究（醛固酮预测术后房颤）的设计
Mathieu Chequel,Pierre Ollitrault,Eric Saloux et al.
Mathieu Chequel et al.
Background: Post-operative atrial fibrillation (POAF) is a major and frequent complication occurring after cardiac surgery, contributing to prolonged intensive care and hospital stays and is associated with several cardio...
Musa Ahmed,Abir Rghigh
Musa Ahmed
Endothelin-1, (ET-1, EDN1) is an endogenous polypeptide which demonstrates dominant vasoconstriction activity and mitogenic effect. It has positive inotropic and chronotropic effects on the heart, stimulates the sympathetic and the renin-an...
Preetika Chandna,Nikhil Srivastava,Sabika Ali
Preetika Chandna
Remineralizing agents represent a new frontier in dentistry. They may be classified as fluoride agents, calcium and phosphate based agents, herbal agents or combinations. The modes of delivery of remineralizing agents may be as dentifrices,...
Incorporating Natural Products, Pharmaceutical Drugs, Self-Care and Digital/Mobile Health Technologies into Molecular-Behavioral Combination Therapies for Chronic Diseases [0.03%]
将天然产品、药物制剂、自我保健和数字/移动卫生技术结合用于慢性病的分子-行为综合疗法
Grzegorz Bulaj,Margaret M Ahern,Alexis Kuhn et al.
Grzegorz Bulaj et al.
Merging pharmaceutical and digital (mobile health, mHealth) ingredients to create new therapies for chronic diseases offers unique opportunities for natural products such as omega-3 polyunsaturated fatty acids (n-3 PUFA), curcumin, resverat...