Interaction of Antipsychotic Drugs with Sucrase, Kinetics and Structural Study [0.03%]
抗精神病药物与蔗糖酶的相互作用及动力学和结构研究
Narges Jafari,Helia Dehganpour,Nava Ghavanini et al.
Narges Jafari et al.
Background: In patients with the Congenital Sucrase-Isomaltase Deficiency (CSID), who lack intestinal sucrase-isomaltase enzyme, a suspension of yeast sucrase is applied as a drug to compensate the enzyme deficiency. Whil...
Comparative Study
Current clinical pharmacology. 2017;12(1):50-54. DOI:10.2174/1574884712666170118145901 2017
Therapeutic Approaches Blocking Glycan Synthesis as Targeting Strategy for Malaria [0.03%]
针对疟疾的治疗策略：通过阻断糖合成发挥作用
Pollyanna S Gomes,Alexandre Morrot
Pollyanna S Gomes
Over one million people die from malaria each year, mainly in the world's tropical and sub-tropical areas. Several research efforts have been devoted to the design of new therapeutic targets for disease control, as drug resistance is one of...
The Combination of New Immunotherapy and Radiotherapy: A N ew Potential Treatment for Locally Advanced Non-Small Cell Lung Cancer [0.03%]
新一代免疫治疗与放疗联合治疗局部晚期非小细胞肺癌的新策略
Paola C Sacco,Paolo Maione,Cesare Guida et al.
Paola C Sacco et al.
Lung cancer is the main reason of cancer death worldwide. About 30% of non-small-cell lung cancer (NSCLC) cases are diagnosed with locally advanced disease (stage III). This is a mixed population including patients who have far more extensi...
Kaushik Guha,Christopher J Allen,Adam Hartley et al.
Kaushik Guha et al.
Ivabradine, acting on the funny channel (If) in the sino-atrial node, reduces myocardial oxygen demand without inducing hypotension. It was developed as a specific bradycardic agent in the 1980s, avoiding the adverse effects of more traditi...
Ravi Kiran Chilivery,Sangilimuthu Alagar,Teepica P Darsini
Ravi Kiran Chilivery
Background: The current study was performed to evaluate the anti-urolithiatic activity of Argemone mexicana L. leaves extracts as natural remedy to over come side effects problem due to the usage of modern synthetic medic...
Comparative Study
Current clinical pharmacology. 2016;11(4):286-290. DOI:10.2174/1574884711666161010143649 2016
Urine Comprehensive Drug Screen, Low Birth Weight and Withdrawal Symptoms in a Neonatal Unit: A Case Control Study [0.03%]
一项关于新生儿病房的尿液综合药物筛查、低体重与戒断症状的病例对照研究
Kam L Hon,Michael H M Chan,Ming H J Ng et al.
Kam L Hon et al.
Objective: Maternal drug abuse may influence neonatal outcomes. We compared neonatal outcomes of patients with urine screened positive for commonly abused drugs (CAD) versus those who were screened negative, and reviewed ...
An Evaluation of the Efficacy of Local Hemostatic Measures in Dental Patients Taking Oral Anticoagulants: A Critical Review of the Literature Over the Past Two Decades [0.03%]
口服抗凝药物患者的局部止血措施的有效性评估：过去二十年文献的批判性回顾
Salomao I M L Queiroz,Helenilton S Alves,Gleysson M de Assis et al.
Salomao I M L Queiroz et al.
The increased risk of bleeding observed in patients on oral anticoagulant therapy (OAT) undergoing outpatient oral surgical procedures has been reported in the literature and remains a major concern in the care of these patients. This is st...
Therapeutic Effects of Rivastigmine and Alfa-Lipoic Acid Combination in the Charles Bonnet Syndrome: Electroencephalography Correlates [0.03%]
利凡斯的明联合硫胺酸治疗查尔斯-邦内特综合征的疗效：脑电图相关性研究
Lutfu Hanoglu,Sultan Yildiz,Burcu Polat et al.
Lutfu Hanoglu et al.
Background: Charles Bonnet Syndrome (CBS) is a rare clinical condition which is characterized by complex hallucinations in visually impaired patients. The pathophysiology of this disorder remains largely unknown, and ther...
An 8-Year Retrospective Study of Human Visceral Leishmaniasis [0.03%]
人 visceral leishmaniasis 的八年回顾性研究
Juliana F Barbosa,Sonia M de Figueiredo,Sandra Lyon et al.
Juliana F Barbosa et al.
Background: Visceral leishmaniasis (VL) is a zooanthroponosis affecting both rural and periurban areas, and can also spread into urban areas. VL has emerged in many countries in the world, presenting new cases in new coun...
Relationships Between Metformin, Paraoxonase-1 and the Chemokine (C-C Motif) Ligand 2 [0.03%]
二甲双胍、弹力酶-1和化学因子(C-C基序)配体2之间的关系
Jordi Camps,Anna Hernandez-Aguilera,Anabel Garcia-Heredia et al.
Jordi Camps et al.
Metformin is a biguanide used in the treatment of type 2 diabetes mellitus and obesity. The main mechanism of action is to decrease the intestinal glucose absorption and the hepatic glucose production, however, it does not influence insulin...