Revolutionizing Drug Delivery: A Design Professional's Approach to Drug-loaded Transferosomal Vesicles for Transdermal Use [0.03%]
药物传输的革新：药载转移osome脂质体的设计开发及透皮应用的专业方法
Gopinath Subramaniyan,Rubina Shaik,Bachu Venkata Ramana et al.
Gopinath Subramaniyan et al.
Aim: This study aimed to develop and evaluate lornoxicam (LXM) and thiocolchicoside (TCS) transferosomal transdermal patches. Background: ...
Dyandevi Mathure,Sejal Bhandare,Dipanjan Karati et al.
Dyandevi Mathure et al.
Even with recent advancements in surgery and multimodal adjuvant therapy, brain cancer treatment is still difficult. The blood-brain barrier and the potentially deadly medications' nonspecificity have made pharmacological treatment for brai...
Enhancing Solubility of a BCS Class II Drug- Itraconazole by Developing and Optimizing Solid Lipid Nanoparticles using a Central Composite Design [0.03%]
使用中央组合设计开发和优化固体脂质纳米粒以增强BCSII类药物伊曲康唑的溶解度
Irfan A Mohammed,Sriramakamal Jonnalagadda
Irfan A Mohammed
Background: Itraconazole (ICZ) has been approved by the FDA to treat many fungal infections including, blastomycosis, histoplasmosis, and aspergillosis. ICZ can be also used as prophylaxis in the population who are at hig...
Polymeric Nano-discs: A Versatile Nanocarrier Platform for Delivering Topical Theranostics [0.03%]
聚合物纳米盘：一种用于输送局部治疗诊断药物的多功能纳米载体平台
Devesh U Kapoor,Mansi Gaur,Hetal Hingalajia et al.
Devesh U Kapoor et al.
Polymeric nano-discs offer a promising and adaptable nanocarrier platform for topical applications involving the targeted administration of drugs. These biocompatible polymer-based, disc-shaped, nanoscale structures have drawn interest due ...
An Enhanced Scrutiny of Mechanistic and Translational Approaches to Extinguish Cancer Hypoxia [0.03%]
熄灭癌症缺氧的机制和转化方法的增强审查
Arun Radhakrishnan,Nikhitha K Shanmukhan,Linda Christabel S
Arun Radhakrishnan
Cancer continues to pose a formidable challenge in global health due to its incidence and increasing resistance to conventional therapies. A key factor driving this resistance is tumor hypoxia, characterized by reduced oxygen levels within ...
Development of Nanoemulsion-Based Gel of Betulin for the Treatment of Psoriasis-Like Skin Inflammation in a Small Animal Model [0.03%]
一种用于治疗小动物模型银屑病样皮肤炎症的betulin纳米乳凝胶制剂的开发
Dev Prakash,Anjali Chaudhari
Dev Prakash
Introduction/ Background: This study aimed to introduce a gel (NEG) formulation containing betulin-loaded nanoemulsions for topical psoriasis treatment. Materials and method...
Somayeh Hajipour,Alireza Ghiasvand
Somayeh Hajipour
The drug was initially administrated relying on pills, eye drops, ointments, and intravenous solutions. In the last decades, several novel technologies have emerged to overcome significant challenges including poor solubility, drug aggregat...
A Comprehensive Review of Strategies of Topical Niosomes and Their Synergistic Effect for Enhanced Therapeutic Outcomes [0.03%]
拓扑nisome策略的全面回顾及其协同作用以增强治疗效果
N Bharathi Sai Thilagam,V P Karthik,C Sowmya et al.
N Bharathi Sai Thilagam et al.
The review aims to assess the potential of niosomes-nonionic surfactant-based vesicular systems-as carriers for topical and transdermal drug delivery. Niosomes enable targeted and controlled drug release while minimizing systemic toxicity. ...
A Comprehensive Review on Plant Bioactive Compounds-Based Novel Drug Delivery System for the Treatment of Rheumatoid Arthritis [0.03%]
基于植物生物活性化合物的新型给药系统治疗类风湿关节炎的研究进展综述
Akshat Agrawal,Vijayalakshmi Ghosh,Ajaz Uddin et al.
Akshat Agrawal et al.
Rheumatoid Arthritis (RA) is a chronic autoimmune disorder characterized by inflammation in the joints, leading to pain, swelling, stiffness, and eventual joint damage. This condition occurs when the body's immune system mistakenly attacks ...
Current Updates on Nanotechnology-based Drug Delivery Platforms for Treating Alzheimer's with Herbal Drugs [0.03%]
基于纳米技术的药物输送平台治疗阿尔茨海默病的草药药物当前更新
Shakeel Ahmed Ansari,Asim Muhammad Alshanberi,Rukhsana Satar et al.
Shakeel Ahmed Ansari et al.
Alzheimer's disease (AD) is an irreversible brain disorder that led to memory loss and disrupts daily life. Earlier strategies to treat AD such as acetylcholinesterase inhibitor (AChEI) drugs are not showing effectiveness due to the inabili...