Xiwei Ji,Wei Lu,Kehua Wu et al.
Xiwei Ji et al.
Background: Nano-pharmaceutics have been actively studied for the encapsulation and targeted delivery of drugs to improve the treatment strategies for various diseases. Because of the size, nano-pharmaceutics show some sp...
Pharmacokinetic Consequences of PLGA Nanoparticles in Docetaxel Drug Delivery [0.03%]
聚乳酸-乙醇酸共聚物纳米粒在多西他赛药物递送中的药代动力学效应
Pedram Rafiei,Azita Haddadi
Pedram Rafiei
Background: Cancer chemotherapy is accompanied with administration of highly potent cytotoxic agents in doses that can result in non-specific drug toxicity and side effects. Chemotherapeutic agents possess limitations suc...
Ijeoma F Uchegbu
Ijeoma F Uchegbu
Rahul Maheshwari,Piyoosh Sharma,Muktika Tekade et al.
Rahul Maheshwari et al.
Background: Nifedipine is a potential therapeutic agent for the treatment of cardiovascular disturbances, although it suffers from short half-life (t1/2, 2 hr). ...
A Self-nanoemulsifying Drug Delivery System for Poorly Water Soluble Tolbutamide: Development, Optimization and Pharmacodynamic Studies [0.03%]
一种难溶于水的 tolbutamide 自微乳化药物传输系统：开发、优化与药动学研究
Deepti Pandita,Neelam Kumari,Viney Lather
Deepti Pandita
Background: Self-nanoemulsifying drug delivery system (SNEDDS) has immense potential in oral bioavailability enhancement of lipophilic drugs. Objective: ...
Design, Optimization and Characterization of Granisetron HCl Loaded Nano-gel for Transdermal Delivery [0.03%]
用于经皮给药的盐酸格拉司琼纳米凝胶的设计、优化及表征研究
Geeta Aggarwal,Vikash Kumar,Hema Chaudhary
Geeta Aggarwal
Background & objective: Our research objective was to design, develop, optimize and characterize Granisetron HCl transdermal gel in order to minimize side effects associated with oral delivery. ...
Development of Timolol Maleate Loaded Chitosan Nanoparticles For Improved Ocular Delivery [0.03%]
硫酸软骨素纳米颗粒的开发，以用于改善眼部递送的噻吗洛尔马来酸盐
Ajay Saroha,Parijat Pandey,Deepak Kaushik
Ajay Saroha
Background: The poor retention and penetration are the major issues in the bioavailability of drugs through ocular route. Recently, the natural polymers have been exploited for the development of nanoparticles to improve ...
Funmilola A Fisusi,Rebecca Notman,Louis A Granger et al.
Funmilola A Fisusi et al.
Background: Conventional nanofiber forming peptide amphiphiles comprise a beta sheet forming, short peptide sequence with an alkyl chain attached at one terminus. We report the selfassembly of a peptide amphiphile possess...
Application of Chitosan and its Derivatives in Nanocarrier Based Pulmonary Drug Delivery Systems [0.03%]
壳聚糖及其衍生物在基于纳米载体的肺部药物递送系统中的应用研究进展
Kamal Dua,Mary Bebawy,Rajendra Awasthi et al.
Kamal Dua et al.
Background: The respiratory tract as a non-invasive route of drug administration is gaining increasing attention in the present time on achieving both local and the systemic therapeutic effects. Success in achieving pulmo...
Vesicular Systems Containing Curcumin and Their Applications in Respiratory Disorders - A Mini Review [0.03%]
载姜黄素囊泡及其在呼吸系统疾病中的应用-综述
Dinesh Kumar Chellappan,Philip Michael Hansbro,Kamal Dua et al.
Dinesh Kumar Chellappan et al.
Background: Vesicular systems like nanotechnology and liposomes are gaining tremendous attention lately in the field of respiratory diseases. These formulations enhance bioavailability of the drug candidate, which could b...