Qian Huang,Huishu Liu,Bihui Hu et al.
Qian Huang et al.
Introduction: Eclampsia is the most serious state of hypertensive disorder in pregnancy, but the pathogenesis of eclampsia seizures is poorly understood. ...
PP012. Abnormal vascular umbilical cord morphology in vascular-related pregnancy complications [0.03%]
血管相关妊娠并发症中的脐带血管异常形态学改变
Emilie Herzog,Anniek Reijnierse,Ronald Krijger de et al.
Emilie Herzog et al.
Background: Preeclampsia (PE), foetal growth restriction (FGR) and preterm birth (PTB) are associated with an increased risk on the development of cardiovascular disease in offspring. Abnormal programming of the embryonic...
PP011. Placental expression of the major protein components of caveolae, eNOS and iNOS in pre-eclampsia [0.03%]
胎盘膜足蛋白主要成分、eNOS和iNOS在子痫前期的表达
Marta Hentschke,Kate Smith-Jackson,Carlos E Poli-de-Figueiredo et al.
Marta Hentschke et al.
Introduction: Caveolins and Cavins are the major protein components of caveolae and regulate many cardiovascular functions. Caveolin-1 inhibits eNOS activity. The possible regulation of vascular reactivity/blood pressure ...
PP007. Nicotinic acetylcholine receptor subunits in the pre-eclamptic and cigarette smoke exposed human placenta [0.03%]
胎盘尼古丁乙酰胆碱受体亚单位在子痫前期和香烟暴露中的变化研究
Emma Ghazavi,Rona David,Tina Hinton et al.
Emma Ghazavi et al.
Introduction: Cigarette smoking during pregnancy is associated with low birth weight, prematurity and neonatal morbidity and mortality. Nicotine, a major constituent of cigarette smoke, binds to nicotinic acetylcholine re...
PP010. Alpha-1-microglobulin protects from heme induced placenta and kidney damage in a pregnant ewe model for preeclampsia [0.03%]
α-1微球蛋白通过保护胎盘和肾脏免受血红素诱导的损伤来预防妊娠 ewe 羊模型中的子痫前期
Anneli Edström-Hägerwall,Stefan Hansson,Vera Casslén et al.
Anneli Edström-Hägerwall et al.
Introduction: Previous gene expression analysis have identified fetal hemoglobin (HbF) as a plausible etiological factor in preeclampsia. Free hemoglobin and its degradation products, e.g. heme, are known to cause oxidati...
PP009. Hypoxia alters syncytiotrophoblastic microparticles (STBM)-related coagulation capacities [0.03%]
缺氧改变合体滋养层微粒相关凝血功能
Claudia Göhner,Dietmar Schlembach,Ekkehard Schleussner et al.
Claudia Göhner et al.
Introduction: Endothelial dysfunction is thought to be the cause of preeclampsia (PE) symptoms. Severe forms of PE are correlated to the release of syncytiotrophoblastic microparticles (STBM), which triggers inflammatory ...
Stefano Raffaele Giannubilo,Monia Cecati,Franca Saccucci et al.
Stefano Raffaele Giannubilo et al.
Introduction: An aging-suppressor gene, klotho, is a candidate factor for vascular disease because its deficiency leads to impaired endothelium-dependent vasodilation and impaired angiogenesis. This protein is involved in...
Louise Bjørkholt Andersen,Florian Herse,Henrik Thybo Christesen et al.
Louise Bjørkholt Andersen et al.
Introduction: Vitamin D may ameliorate hypertension and kidney disease through genomic and extra-genomic pathways. Objective: To invest...
PP006. Gene expression profiling of first trimester placentas from pregnancies at high risk of developing preeclampsia [0.03%]
孕早期高危子痫前期妊娠胎盘基因表达谱分析
Ulrik Dolberg Anderson,Baskaran Thilaganathan,Magnus Gram et al.
Ulrik Dolberg Anderson et al.
Introduction: Preeclampsia (PE) is an important cause of fetal and maternal morbidity and mortality. It is considered a two-stage disease, the first stage characterized by a defect placentation and the second stage by mat...
PP004. The polymorphism C677T of methylenetetrahydrofolate reductase (MTHFR), may increase risk for future higher blood pressure in women with previous hypertension in pregnancy [0.03%]
甲基四氢叶酸还原酶（MTHFR）的多态性C677T可能会增加既往妊娠期高血压妇女未来发生较高血压的风险
Andreia Matos,Alda Pereira da Silva,Helena Maia et al.
Andreia Matos et al.
Introduction: The MTHFR is a key enzyme in the folate cycle involved in homocysteine remethylation. The T allele of MTHFR C677T polymorphism is associated with lower activity inhibiting the DNA methylation and protecting ...