Endoplasmic reticulum stress in the pathogenesis of early-onset pre-eclampsia [0.03%]
内质网应激在早期子痫前期发病机制中的作用
Graham J Burton,Hong-Wa Yung
Graham J Burton
Recent data have provided molecular evidence of high levels of endoplasmic reticulum stress in non-laboured placentas from cases of early-onset pre-eclampsia. Endoplasmic reticulum stress is intricately linked to oxidative stress, and the t...
The Impact of Preeclampsia on Gene Expression at the Maternal-Fetal Interface [0.03%]
子痫前期对母胎界面基因表达的影响
Virginia D Winn,Matthew Gormley,Susan J Fisher
Virginia D Winn
Preeclampsia (PE) impacts 8 million mother-infant pairs worldwide each year. This human pregnancy-specific disease characterized by hypertension and proteinuria accounts for significant maternal and neonatal morbidity and mortality. The cur...
Isha Agarwal,S Ananth Karumanchi
Isha Agarwal
Preeclampsia is a major cause of maternal and fetal morbidity and mortality worldwide, however, its etiology remains unclear. Abnormal placental angiogenesis during pregnancy resulting from high levels of anti-angiogenic factors, soluble Fl...
James M Roberts,Lisa M Bodnar,Thelma E Patrick et al.
James M Roberts et al.
The incidence of obesity is increasing at an alarming rate. There is compelling evidence that obesity increases the risk of preeclampsia about 3-fold, and in developed countries is the leading attributable risk for the disorder. In this pre...