PP045. Different associations between phenotypes of preeclampsia and thrombophilias [0.03%]
子痫前期的临床表型与遗传性易栓症的关系分析
Durk Berks,Hans Duvekot,Hillal Basalan et al.
Durk Berks et al.
Introduction: Studies on the association of preeclampsia (PE) with thrombophilias (TRPH) are conflicting. Clinical heterogeneity of PE may be one of the explanations. ...
PP044. Differential expression of trophoblast-, endothelial- and embryonic stem cell-associated transcription factors in 1st trimester, and in 3rd trimester preeclampsia and intrauterine growth restriction [0.03%]
滋养层、内皮和胚胎干细胞相关转录因子在早期妊娠以及晚期先兆子痫和宫内发育迟缓妊娠中的表达差异
Maja Weber,Dietmar Schlembach,Ekkehard Schleussner et al.
Maja Weber et al.
Objectives: Trophoblast progenitor cells express stem cells markers (SCM) to maintain the proliferative characteristic of stem cells. Beyond blastocyst stage or in preeclampsia (PE) or intrauterine growth restriction (IUG...
PP042. Cell surface toll-like receptors in primary first trimester trophoblasts [0.03%]
特异人早孕滋养细胞表面 Toll 样受体的表达及功能研究
Line Haugstad Tangerås,Guro Sannerud Stødle,Guro Dalheim Olsen et al.
Line Haugstad Tangerås et al.
Introduction: The first trimester of pregnancy is characterised by a mild pro-inflammatory environment, however excessive inflammation threatens placental development and function. Toll-like receptors (TLRs) are crucial i...
PP039. ETK/BMX and renin-angiotensin system (RAS) components are differentially expressed in renal tissue in both normal and preeclamptic pregnancy [0.03%]
ETK/BMX和肾素血管紧张素系统(RAS)组分在正常和先兆子痫妊娠的肾脏组织中的差异表达
Helena Strevens,Lesia Kurlak,Hiten Mistry et al.
Helena Strevens et al.
Introduction: Renal ETK/BMX activity is reduced in preeclampsia. Systemic RAS has been studied in preeclampsia; the renal RAS has not. None of the proteins in either pathway have previously been located in renal tissue fr...
PP040. Activation of endosomal toll-like receptors in first trimester trophoblasts [0.03%]
蜕膜自然杀伤细胞的起源和功能异质性
Guro Stødle,Line Haugstad Tangerås,Guro Dalheim Olsen et al.
Guro Stødle et al.
Introduction: A mild systemic inflammation may be beneficial to normal pregnancy, however exaggerated inflammation may contribute to pregnancy complications. Infections and cell stress or damage may evoke placental inflam...
PP041. The underlying mechanisms in reduced action of endothelial nitric oxide in resistance artery in preeclampsia [0.03%]
PPEC041.妊娠高血压综合征中抵抗性动脉内皮衍生一氧化氮作用降低的潜在机制研究
Yoshikatsu Suzuki,Tamao Yamamoto
Yoshikatsu Suzuki
Objective: In preeclampsia (PE), the action of endothelial nitric oxide (eNO) is reduced by in vitro investigation of characteristic changes using vascular strips of resistance artery. We studied underlying mechanisms in ...
Helena Strevens,Dag Wide-Swensson,Ola Hansson et al.
Helena Strevens et al.
Introduction: Vascular endothelial growth factors (VEGF's) are essential to angiogenesis and play a central role in the pathophysiology of preeclampsia. Specifically, antagonists of VEGFR2 cause a preeclampsia-like syndro...
PP037. Relationship of serum leptin levels to circulating cytokines, chemokines, adhesion molecules and angiogenic factors in women with preeclampsia [0.03%]
妊娠高血压疾病患者血清瘦素水平与循环细胞因子、趋化因子、粘附分子和血管生成因子的关系
János Rigó Jr,András Szarka,Attila Molvarec
János Rigó Jr
Introduction: Serum leptin levels are known to be increased in preeclampsia. Objectives: To determine circulating levels of leptin alon...
PP036. The intrarenal renin-angiotensin system and pregnancy outcome [0.03%]
PP036. 肾内肾素血管紧张素系统与妊娠结局
Kirsty Pringle,Eugenie Lumbers,Shane Sykes et al.
Kirsty Pringle et al.
Objectives: The intrarenal renin angiotensin system (iRAS) may be activated in normal pregnancy. Failure of activation may predispose to preeclampsia. Met...
PP034. Renal histology in preeclampsia: A special role for the podocyte [0.03%]
子痫前期的肾小球病理表现：足细胞发挥重要作用
Marlies Penning,Kitty Bloemenkamp,Joke Schutte et al.
Marlies Penning et al.
Introduction: In preeclampsia (PE), the kidney is one of the major target organs. Growing evidence suggests PE increases the risk of subsequent microalbuminuria and end-stage renal disease (ESRD). Endotheliosis and podocy...