PP054. Elevated maternal plasma glycogen phosphorylase isoenzyme BB as time of disease biomarker of pre-eclampsia and small-for-gestational-age [0.03%]
妊娠期高血压疾病发病时间的生物标志物：母体血浆糖原磷酸化酶同工酶BB水平升高与胎儿宫内发育迟缓的关系研究
Louise Kenny,Aisling Doyle,Ali Khashan
Louise Kenny
Introduction: Glycogen phosphorylase isoenzyme BB (GPBB) is a marker of acute coronary syndromes. Pre-eclampsia (PE) and coronary syndrome share several aetiological and pathophysiological features. GPBB levels have previ...
PP053. The role of peroxisome proliferator-activated receptor gamma co-activator 1-alpha in pregnancy [0.03%]
PP053.孕产期过氧化物酶体增殖激活受体γ共激活因子1α的作用
Aoife Delany,Fergus McCarthy,Sarah Walsh et al.
Aoife Delany et al.
Introduction: PGC-1α is a transcriptional co-activator that drives mitochondrial biogenesis in many tissues, including cardiac. PGC-1α is a powerful regulator of angiogenesis, a process of fundamental importance to the ...
PP051. Budget impact analysis of maternal plasma PIGF concentrations in women with suspected pre-eclampsia: The potential for improved health service usage [0.03%]
疑似子痫前期孕妇母体血浆PIGF浓度的预算影响分析：改善医疗服务使用的潜力
Rachael Hunter,Suzy Duckworth,Paul Seed et al.
Rachael Hunter et al.
Introduction: Existing methods of assessing women with suspected pre-eclampsia are expensive and labour intensive, yet perform poorly. Objectives and meth...
PP052. Diagnosis of pre-eclampsia and prediction of time to delivery in women with suspected pre-eclampsia presenting before 36 weeks' gestation [0.03%]
PP052．评估小于36孕周疑似子痫前期患者的子痫前期诊断和预测分娩时间
Claudia Daubert,Christine Morfeld,Ralf Schild
Claudia Daubert
Introduction: The pro-angiogenic factor PlGF has an important role in the development and maintenance of the placenta. Incomplete remodelling of uterine spiral arteries is associated with placental oxidative stress, place...
PP050. NT-Pro-BNP: Correlation with adverse outcome markers in hypertensive gestational syndromes [0.03%]
妊娠高血压综合征中NT-pro-BNP与不良预后标志物的相关性研究
Marcela Clelia Cabo Fustaret,Ana Escobar,Ricardo Illia et al.
Marcela Clelia Cabo Fustaret et al.
Introduction: Brain-type natriuretic peptide is released by cardiomyocites in response to parietal stress augmentation and systemic endothelial dysfunction. Hypertensive Gestational Syndromes (HGS) share this mechanism, b...
PP048. Carotid intima-media-thickness in the first trimester as a predictor of preeclampsia [0.03%]
妊娠早期颈动脉内膜中层厚度预测子痫前期价值的研究
Andreas Brueckmann,Christin Seeliger,Dietmar Schlembach et al.
Andreas Brueckmann et al.
Introduction: Carotid intima media thickness (IMT) is an established marker for endothelial dysfunction and cardiovascular risk. The aim of this study was to assess IMT in the first trimester and it's predictive value for...
PP047. Fetal gender specific differences in markers of placentation and maternal adaptation to pregnancy - The generation R study [0.03%]
基于胎盘标志物和孕妇对妊娠适应性的 GenerationR 研究中的性别差异分析
Zoe Brown,Sarah Timmermans,Eric Steegers
Zoe Brown
Introduction: Evidence indicates a gender specific interaction between the mother, placenta and fetus in which maternal adaptation to pregnancy and outcome partly depends on fetal gender. ...
PP049. The arterio-venous ratio of retinal vessels in the first trimester as a predictor for preeclampsia [0.03%]
早孕期视网膜动静脉比作为预测子痫前期的标志物
Andreas Brueckmann,Christin Seeliger,Markus Schwefer et al.
Andreas Brueckmann et al.
Introduction: Retinal changes are known in severe preeclampsia (PE). This is the first study evaluating static retinal vessel analysis in pregnancy to measure retinal vessel diameter and in women destined to develop preec...
PP046. A unique urinary proteome profile at 15 weeks' gestation in low-risk women with subsequent pre-eclampsia [0.03%]
孕15周低风险孕妇先兆子痫的特异性尿液蛋白谱特征
Kate Bramham,Hiten Mistry,Steven Lynham et al.
Kate Bramham et al.
Introduction: Pre-eclampsia remains one of the leading causing of maternal and perinatal morbidity and mortality. Recent plasma biomarker discovery has improved the diagnosis of pre-eclampsia; however no factors which are...
PP043. Oxidative stress in the maternal body also affects the fetus in preeclamptic women with fetal growth restriction [0.03%]
子痫前期合并胎儿生长受限孕妇母体氧化应激对胎儿的影响
Kazushi Watanabe,Ai Iwasaki,Toshitaka Mori et al.
Kazushi Watanabe et al.
The purpose of the present study was to determine whether oxidative stress occurring in the maternal body also affects the fetus in preeclamptic women with FGR. We ∥@consecutively recruited 17 preeclamptic women with FGR, 16 preeclamptic w...