OP003. Placental perfusion in normal pregnancy and in early and late preeclampsia: A magnetic resonance imaging study [0.03%]
基于磁共振成像的正常妊娠及子痫前期早期和晚期胎盘灌注研究
Sohlberg Sara,Lindgren Peter,Lutvica Ajlana et al.
Sohlberg Sara et al.
Introduction: Placental perfusion is of key interest for the understanding of the pathophysiology of different types of preeclampsia (PE). With magnetic resonance imaging (MRI) perfusion can be estimated non-invasively by...
OP004. A SNP associated with susceptibility to preeclampsia near the inhibin, beta B gene, is also associated with cardiovascular disease risk traits [0.03%]
临近抑制素βB基因与先兆子痫易感性相关的SNP也与心血管疾病风险特征相关
Mari Løset,Matthew P Johnson,Phillip E Melton et al.
Mari Løset et al.
Introduction: It is well established that preeclampsia (PE) increases later life cardiovascular disease (CVD) risk. Consequently, PE has started to gain a role as an early screening criterion for CVD. PE and CVD share sev...
OP001. A longitudinal study of maternal vascular reactivity, circulating endothelial progenitor cells and inflammatory response during the second half of pregnancy [0.03%]
课题编号OP001：孕期后半段母亲血管反应性、循环内皮祖细胞和炎症反应的纵向研究
Flo Kari,Husebekk Anne,Vårtun Åse et al.
Flo Kari et al.
Introduction: Maternal endothelial dysfunction and inflammation are associated with hypertensive pregnancy disorders. Objectives: To in...
OP002. Impact of the NO-donor pentaerythrithyltetranitrate on perinatal outcome in high-risk pregnancies: A prospective randomized double blinded pilot study [0.03%]
一氧化氮供体右美尼莫硝酸酯对高危妊娠围产结局影响的前瞻性随机双盲临床研究
Schlembach Dietmar,Groten Tanja,Lehmann Thomas et al.
Schlembach Dietmar et al.
Objective: To evaluate the effectiveness of the oral NO-donor PETN in secondary prevention of intrauterine growth restriction (IUGR), preterm birth and preeclampsia in high risk pregnancies. ...
Paul Leeson
Paul Leeson
Preeclampsia is well established as one of the leading causes of maternal and fetal mortality and morbidity. Furthermore, it is now clear that women who have had preeclampsia have an increased risk of cardiovascular events over the next 10-...
A multi-centre phase IIa clinical study of predictive testing for pre-eclampsia. IMproved PRegnancy Outcomes Via Early Detection (IMPROVED) [0.03%]
预测检测子痫前期的多中心IIa期临床研究。通过早期检测改善妊娠结局（IMPROVED）
Louise Kenny;IMPROVED Consortium
Louise Kenny;IMPROVED Consortium
1 in 20 first time pregnancies is complicated by pre-eclampsia, the leading cause of maternal death in Europe. No clinically useful early pregnancy screening test exists, consequentially clinicians are unable to offer targeted surveillance ...
Hannele Laivuori
Hannele Laivuori
This presentation will consider approaches to discover susceptibility genes for a complex genetic disorder such as preeclampsia. The clinical disease presumably results from the additive effects of multiple sequence variants from the mother...
Maternal circulating PlGF concentrations and placenta-related pregnancy complications: First results from the CoLab AngF Study [0.03%]
母体循环PlGF浓度与胎盘相关妊娠并发症的关系：CoLab AngF研究的初步结果
A C Staff,Ó Burke,S Benton et al.
A C Staff et al.
Introduction: Circulating angiogenic factors are potential markers for preeclampsia, but heterogeneous studies have failed to identify precise predictive/diagnostic properties. The Global CoLaboratory is investigating how...
Linda Morgan
Linda Morgan
Over half of the familial predisposition to pre-eclampsia can be attributed to genetic factors in the mother and/or fetus. The search for genetic susceptibility variants has progressed through candidate gene studies, family-based linkage st...
Developing potential biomarkers for preeclampsia: Why is the current strategy failing? [0.03%]
妊娠高血压综合征潜在生物标志物的研究：目前研究策略的弊端是什么？
Berthold Huppertz
Berthold Huppertz
During the last decade major progress has been achieved in identifying new predictive biomarkers as well as setting up screening strategies for preeclampsia. A number of biochemical markers in combination with biophysical markers coupled to...