PP003. Heat shock protein 27 expression is spatially distributed in human placenta and selectively regulated during preeclampsia [0.03%]
人胎盘热休克蛋白27的表达具有空间分布的特点并在妊娠高血压综合征中选择性调节
Akrem Abdulsid,Fiona Lyall
Akrem Abdulsid
Introduction: Placental oxidative stress is a feature of the pregnancy syndrome preeclampsia. Heat shock proteins (HSPs) can be induced in cells as a protective mechanism to cope with cellular stress. We hypothesized that...
PP001. The vascular tree during pregnancy and at follow-up - A longitudinal study of maternal vascular function [0.03%]
孕期及随访期间的血管树--一项关于母亲血管功能的纵向研究
Ellika Andolf,Thomas Kahan,Charlotte Iacobaeus et al.
Ellika Andolf et al.
Introduction: Normal maternal vascular function and optimal cardiovascular adaptation to the increasing demands of pregnancy is a prerequisite for a successful outcome of pregnancy. How different levels of the vascular tr...
PP002. Metabolomic biomarkers in serum and urine of preeclamptic women [0.03%]
子痫前期患者血清及尿液代谢组生物标志物研究
Marie Austdal,Ragnhild Bergene Skråstad,Astrid Solberg Gundersen et al.
Marie Austdal et al.
Introduction: Preeclampsia (PE) affects about 3% of pregnancies. The syndrome cannot be accurately predicted, and large variation complicates the search for early biomarkers. Metabolites are components of the metabolism; ...
Individual artery wall layer dimensions indicate increased cardiovascular risk in previous severe preeclampsia -an investigation using non-invasive high-frequency ultrasound [0.03%]
应用高频率超声检测技术评估子痫前期患者动脉壁各层厚度及心血管风险增加情况
Akhter Tansim,Larsson Marita,Wikström Anna-Karin et al.
Akhter Tansim et al.
Background: Preeclampsia (PE) is associated with increased risk for cardiovascular disease later in life. Studies using gold standard of non-invasive estimation of atherosclerosis, the common carotid artery intima-media-t...
OP0011. Impaired autophagy in extravillous trophoblast may induce poor placentation in preeclampsia [0.03%]
极重度子痫前期患者合体滋养细胞自噬受损可能导致胎盘着床不良
Saito Shigeru,Nakashima Akitoshi
Saito Shigeru
Shallow invasion of extravillous trophoblast (EVT) and inadequate vascular remodeling by EVT are the major cause of poor placentation in preeclampsia. In early pregnancy period, trophoblast experience hypoxic and low-nutrient condition. Aut...
OP0010. Optimizing time from diagnosis to delivery in preeclampsia based on the future health prospects of offspring [0.03%]
子癇前期诊断到分娩时间的优化以期改善后代未来的健康状况
Jacob Alexander Lykke,Jacobus J Boomsma,Birgitte Hollegaard
Jacob Alexander Lykke
Introduction: Limited data exist on long-term health-consequences of maternal preeclampsia for offspring. Objectives: We investigated l...
OP008. Different dysregulation of placental mirnas in early- and late-onset preeclampsia [0.03%]
子痫前期患者胎盘mirna的异常表达与其发生的时间相关
M Susanne Weedon-Fekjær,Ying Sheng,Florian Herse et al.
M Susanne Weedon-Fekjær et al.
Introduction: miRNAs are small ∼22nt RNAs, important in the fine-tuning of mRNA in many organs including placenta. Preeclampsia (PE) is a heterogenous disease which may be divided into early-onset PE, which is a more sev...
OP005. Preeclampsia is associated with the presence of transcriptionally active placental fragments in the maternal lung [0.03%]
前置胎盘导致妊娠高血压与孕妇肺部存在具有转录活性的胎盘片段有关
Buurma Aletta,Penning Marlies,Prins Frans et al.
Buurma Aletta et al.
Introduction: Preeclampsia is associated with increased levels of the circulating anti-angiogenic factor sFlt-1 as well as with an excessive shedding of placenta-derived multinucleated syncytial aggregates into the matern...
OP007. PLGF in combination with other commonly utilised tests and other biomarkers for predicting need for delivery for pre-eclampsia within 14days in women presenting prior to 35weeks' gestation [0.03%]
胎龄小于35周的子痫前期孕妇在两周内需要分娩高风险预测模型的研究：PLGF与其他常用检查及生物标志物联合应用的价值研究
Chappell Lucy,Duckworth Suzy,Griffin Melanie et al.
Chappell Lucy et al.
Introduction: Current means of assessing women presenting with suspected pre-eclampsia using BP and proteinuria are of limited use in predicting need for imminent delivery. ...
OP006. A preeclampsia genome-wide linkage scan in norwegian families [0.03%]
挪威家族的子痫前期全基因组连锁扫描（OP006）
Linda Tømmerdal Roten,Matthew P Johnson,Liv Cecilie V Thompsen et al.
Linda Tømmerdal Roten et al.
Introduction: Several maternal susceptibility loci for preeclampsia (PE) have been discovered amongst Icelandic, Australian/New Zealand, Dutch and Finnish family cohorts, implicating locus heterogeneity. Through candidate...