Toon J I De Munck,Pauline Verhaegh,Toine Lodewick et al.
Toon J I De Munck et al.
Background and aim: Insulin resistance (IR) plays a central role in the complex pathophysiology of nonalcoholic fatty liver disease (NAFLD). IR is linked to fat infiltration in skeletal muscle (myosteatosis) and loss of s...
Portal cavernoma or chronic non cirrhotic extrahepatic portal vein obstruction [0.03%]
门静脉瘤样扩张或慢性肝外门静脉阻塞
Laure Elkrief,Pauline Houssel-Debry,Oanez Ackermann et al.
Laure Elkrief et al.
Chronic non cirrhotic extrahepatic portal vein obstruction (EHPVO) refers to the cavernomatous transformation of the portal vein (the so-called "portal cavernoma") which occurs following acute thrombosis of the portal vein in the absence of...
Mutation pattern and methylation susceptibility of Hepatitis B virus American genotypes [0.03%]
美国基因型乙型肝炎病毒的变异模式和甲基化易感性
Rossana C Jaspe,Carmen L Loureiro,Isabelle Chemin et al.
Rossana C Jaspe et al.
Thierry Thévenot,Laurent Savale,Olivier Sitbon
Thierry Thévenot
Drastic decrease of urgent endoscopies outside regular working hours during the Covid-19 pandemic in the paris area [0.03%]
新冠疫情期间巴黎地区正常工作时间外紧急内镜检查大幅减少
Aymeric Becq,Benedicte Jais,Clémence Fron et al.
Aymeric Becq et al.
Background and study aims: The coronavirus 2019 (COVID-19) pandemic has significantly affected medical care. We surmise that the number of urgent endoscopies outside regular working hours in the Paris area decreased as a ...
Severe immune-related hepatitis induced by immune checkpoint inhibitors: Clinical features and management proposal [0.03%]
免疫检查点抑制剂引起的重度免疫相关性肝炎:临床特征和管理建议
Marie-Léa Gauci,Barouyr Baroudjian,Ulysse Bédérède et al.
Marie-Léa Gauci et al.
Background: Immune-related hepatitis (IRH) occurs in 1 to 18% of immune checkpoint inhibitor (ICI)-treated patients. Steroids are usually recommended for grade≥3 IRH, but their impact on IRH resolution and patient surviv...
Lisa F Barrett,Kevin Bryan Lo,Steven R Stanek et al.
Lisa F Barrett et al.
What is the impact of hepatic steatosis on liver stiffness in patients with chronic hepatitis B? [0.03%]
肝脂肪变性对慢性乙型肝炎患者肝脏硬度的影响是什么?
Noémi Reboux,Jean-François Cadranel,Jean-Baptiste Nousbaum
Noémi Reboux
Ubiquitin-conjugating enzyme E2T(UBE2T) promotes colorectal cancer progression by facilitating ubiquitination and degradation of p53 [0.03%]
泛素耦联酶E2T(UBE2T)通过促进p53的泛素化和降解来促进结直肠癌进展
Mengqiong Wu,Xianglu Li,Weiwei Huang et al.
Mengqiong Wu et al.
Objectives: The expression level of Ubiquitin-conjugating enzyme E2T (UBE2T) is upregulated in various types of human tumors. We explored the correlation and regulatory mechanism of UBE2T in the development of colorectal ...
Oral ibuprofen promoted cholestatic liver disease in very low birth weight infants with patent ductus arteriosus [0.03%]
口服布洛芬促进先天性动脉导管未闭的极低体重婴儿胆汁淤积性肝病的发展
Xintian Shen,Yie Huang,Huijuan Guo et al.
Xintian Shen et al.
Objectives: Hemodynamically significant patent ductus arteriosus (hsPDA) in very low birth weight (VLBW) infants is routinely treated in many countries with oral ibuprofen. This study retrospectively assessed whether the ...