Long noncoding RNA PVT1 promotes tumour progression via the miR-128/ZEB1 axis and predicts poor prognosis in esophageal cancer [0.03%]
长链非编码RNA PVT1通过miR-128/ZEB1轴促进食管癌进展并预示不良预后
Jing Hu,Weifang Gao
Jing Hu
Purpose: To confirm the value of PVT1 as a prognostic marker both in tumour tissue and serum of patients with esophageal cancer and clarify the mechanism. ...
Neutrophil extracellular traps induced by pro-inflammatory cytokines enhance procoagulant activity in NASH patients [0.03%]
促炎症细胞因子诱导的中性粒细胞胞外诱捕网增强NASH患者的促凝血活性
Jingwen Du,Jinming Zhang,Xiaojing Chen et al.
Jingwen Du et al.
Background: Nonalcoholic steatohepatitis (NASH) patients are at a high risk of developing venous thromboembolism, with a high rate of morbidity and mortality. The role of neutrophil extracellular traps (NETs) in procoagul...
Palliation of malignant esophageal obstruction using an anti-migration self-expandable metal stent: Results of a prospective multicenter study [0.03%]
应用防迁移自膨式金属支架治疗恶性食管狭窄的疗效分析：一项前瞻性多中心研究
Massimo Conio,Maria Flavia Savarese,Rosa Angela Filiberti et al.
Massimo Conio et al.
Background: Self-expanding metal stents (SEMS) placement is primarily indicated to palliate dysphagia for patients with expected short-term survival. We aimed to assess the migration rate and other stent-related adverse e...
Low serum alkaline phosphatase levels in patients with chronic liver diseases: Possible contributions to disease pathogenesis [0.03%]
慢性肝病患者低血清碱性磷酸酶水平：可能对疾病发病机制的贡献
Daniel Iluz-Freundlich,Micah Grubert Van Iderstine,Julia Uhanova et al.
Daniel Iluz-Freundlich et al.
Objectives: A low serum alkaline phosphatase (ALP) level is an uncommon finding in patients with chronic liver disease (CLD). The prevalence of this finding and whether low ALP expression influences CLD remain to be deter...
Practices and expectations on the use of circulating tumor DNA in colorectal cancer patients: A bi-national AGEO/AIOM/GERCOR/FFCD/FRENCH survey [0.03%]
关于结直肠癌患者循环肿瘤DNA应用实践和期望的国际调查研究报告
Debora Basile,Claire Gallois,Fabio Puglisi et al.
Debora Basile et al.
Background: Increasing evidence shows that circulating tumor DNA (ctDNA) is a valuable tool in providing molecular, prognostic, predictive and dynamic information in colorectal cancer (CRC) patients. This study aimed to m...
Hepatocellular carcinoma: French Intergroup Clinical Practice Guidelines for diagnosis, treatment and follow-up (SNFGE, FFCD, GERCOR, UNICANCER, SFCD, SFED, SFRO, AFEF, SIAD, SFR/FRI) [0.03%]
肝细胞癌的诊断、治疗和随访：法国跨学科协会临床实践指南(SNFGE，FFCD，GERCOR，UNICANCER，SFCD，SFED，SFRO，AFEF，SIAD，SFR/FRI)
Jean Frédéric Blanc,Audrey Debaillon-Vesque,Gaël Roth et al.
Jean Frédéric Blanc et al.
Introduction: This document is a summary of the French Intergroup guidelines regarding the management of hepatocellular carcinoma (HCC) published in March 2019. ...
Novel albumin, bilirubin and platelet criteria for the exclusion of high-risk varices in compensated advanced chronic liver disease: A validation study [0.03%]
用于排除代偿期晚期慢性肝病高危静脉曲张的新型白蛋白、胆红素和血小板标准：一项验证研究
Yu Jun Wong,Guan Sen Kew,Poh Seng Tan et al.
Yu Jun Wong et al.
Background and aims: Availability of transient elastography (TE) limits the application of Baveno-VI criteria. In a derivation study, the ABP criteria (Albumin >40 g/l, Bilirubin 114,000/μl) had been shown to perform wel...
Increased sTREM-1 levels identify cirrhotic patients with bacterial infection and predict their 90-day mortality [0.03%]
循环中sTREM-1水平升高的临床意义及其对肝硬化患者病死率的预测价值
David Tornai,Zsuzsanna Vitalis,Alexa Jonas et al.
David Tornai et al.
Background and aims: Patients with cirrhosis are susceptible to bacterial infections (BIs) that are major causes of specific complications and mortality. However, the diagnosis of BIs can often be difficult in advanced di...
Is targeting autophagy a promising lead to unveil the cloak of invisibility in pancreatic cancer? [0.03%]
靶向自噬能否成为揭示胰腺癌隐身斗篷的突破口？
C Cayron,S Rigal,J Guillermet-Guibert
C Cayron
Pancreatic ductal adenocarcinoma PDAC is considered as one of the less immunogenic solid tumor types. Pancreatic tumors are also known to present a high autophagy flux which supports tumor progression. Autophagy was recently described as a ...
Thermal ablation of medium-sized hepatocellular carcinomas using intraoperative ultrasound fusion imaging: A propensity score-matched analysis [0.03%]
使用术中超声融合影像技术治疗中型肝细胞癌的热消融疗效分析：倾向性匹配分析
Liping Luo,Xuqi He,Kai Li et al.
Liping Luo et al.
Objective: To explore the value of ultrasound fusion imaging for the thermal ablation of medium-sized hepatocellular carcinomas (HCCs). Materials and meth...