Jérôme Boursier,Maeva Guillaume,Charlotte Bouzbib et al.
Jérôme Boursier et al.
NAFLD is a frequent disease that affects 25% of the worldwide population. There is no specific diagnostic test for NAFLD, and the diagnosis mainly relies on the elimination of the other causes of chronic liver diseases with liver biopsy kep...
Edouard Bardou-Jacquet,Houda Hamdi-Roze,Anita Paisant et al.
Edouard Bardou-Jacquet et al.
Increased serum ferritin is a very frequent cause of referral for which thorough evaluation is required to avoid unnecessary exploration and inaccurate diagnosis. Clinicians must thus know factors and tools that are relevant in this setting...
Jérôme Dumortier,Camille Besch,Lucile Moga et al.
Jérôme Dumortier et al.
The field of liver transplantation directly or indirectly embodies all liver diseases, in addition to specific ones related to organ rejection (cellular and humoral). The recommended non-invasive methods for determining the indication for l...
Pierre-Emmanuel Rautou,Laure Elkrief,Marie Decraecker et al.
Pierre-Emmanuel Rautou et al.
Vascular disorders of the liver are rare diseases, some of which are diagnosed mainly with non-invasive tests and others by liver biopsy. Non-invasive methods can be used to diagnose and monitor these diseases. However, their evaluation nee...
Non-invasive diagnosis and follow-up of chronic infection with Hepatitis C Virus [0.03%]
无创诊断和随访慢性丙型肝炎病毒感染患者
Albert Tran,Sarah Shili-Masmoudi,Lucile Moga et al.
Albert Tran et al.
Hepatitis C virus (HCV) infection is a major cause of chronic liver disease. Clinical care for patients with HCV-related liver disease has advanced considerably with developments in screening, diagnostic procedures to evaluate liver fibrosi...
Dominique Thabut,Delphine Weil,Charlotte Bouzbib et al.
Dominique Thabut et al.
Compensated advanced chronic liver disease (cACLD) describes the spectrum of advanced fibrosis/cirrhosis in asymptomatic patients at risk of developing clinically significant portal hypertension (CSPH, defined by a hepatic venous pressure g...
Rodolphe Sobesky,Olivier Guillaud,Charlotte Bouzbib et al.
Rodolphe Sobesky et al.
Rare genetic liver diseases can result in multi-systemic damage, which may compromise the patient's prognosis. Wilson's disease and alpha-1 antitrypsin deficiency must be investigated in any patient with unexplained liver disease. Cystic fi...
Sara Lemoinne,Alexandra Heurgue,Charlotte Bouzbib et al.
Sara Lemoinne et al.
Autoimmune hepatitis (AIH) is a liver disease characterised by necrotico-inflammatory lesions of hepatocytes, the presence of specific autoantibodies and response to corticosteroid treatment. AIH must be considered in any patient with acute...
Inhibition of USP11 sensitizes gastric cancer to chemotherapy via suppressing RhoA and Ras-mediated signaling pathways [0.03%]
USP11抑酶素通过抑制RhoA和Ras介导的信号通路增强胃癌化疗敏感性
Hongfang Liu,Mei Liu,Bin He et al.
Hongfang Liu et al.
Background: The poor outcomes in advanced gastric cancer (GC) necessitate alternative therapeutic strategy. Ubiquitin-specific protease 11 (USP11) has recently garnered attention as a therapeutic target in cancer because ...
Mobile app requirements for patients with rare liver diseases: A single center survey for the ERN RARE-LIVER [0.03%]
罕见肝病患者的移动应用程序需求：ERN RARE-LIVER单中心调查结果摘要
Darius F Rüther,Marcial Sebode,Ansgar W Lohse et al.
Darius F Rüther et al.
Background: More patient data are needed to improve research on rare liver diseases. Mobile health apps enable an exhaustive data collection. Therefore, the European Reference Network on Hepatological diseases (ERN RARE-L...