Biomarker for infection in children with decompensated chronic liver disease: Neutrophilic CD64 or procalcitonin? [0.03%]
CD64与procalcitonin在儿童肝硬化失代偿期感染标志物中的应用
Vignesh Vinayagamoorthy,Anshu Srivastava,Anamika Kumari Anuja et al.
Vignesh Vinayagamoorthy et al.
Objective: Biomarkers with high accuracy for identification of infection in decompensated chronic liver disease (DCLD) are urgently needed. We compared the accuracy of neutrophilic cluster of differentiation 64 (nCD64) wi...
Laparoscopic anatomical right hepatectomy using a four-incision anterior approach: Technical details and surgical outcomes (with Video) [0.03%]
四切口前入路解剖性右半肝切除术的手术要点及临床疗效（附视频）
Cong Liu,Haoling Liu,Maria A Parra et al.
Cong Liu et al.
With the continuous advancements of laparoscopic techniques, many surgeons have enhanced the feasibility and safety of this approach for carefully selected patients. This study aims to offer a comprehensive account of the technical aspects ...
The construction of a prognostic model by apoptosis-related genes to predict survival, immune landscape, and medication in cholangiocarcinoma [0.03%]
基于凋亡相关基因的胆管癌预后模型的构建及其在生存预测、免疫景观和用药指导中的应用研究
Peng Shen,Yinsheng Shi,Pengcheng Xu et al.
Peng Shen et al.
Background: Cholangiocarcinoma (CCA) is a highly aggressive and invasive malignant tumor of the bile duct, with a poor prognosis and a high mortality rate. Currently, there is a lack of effective targeted treatment method...
Yulei Tao,Chunming Cheng
Yulei Tao
Dysregulation of the polyamine metabolism is common in different cancer types. SMOX is upregulated in hepatocellular carcinoma (HCC) but the relationship between SMOX and liver inflammation and fibrosis, remains unclear. In this issue of Cl...
Silymarin suppresses proliferation and PD-L1 expression in colorectal cancer cells and increases inflammatory CD8+ cells in tumor-bearing mice [0.03%]
奶蓟素通过增加携带肿瘤小鼠中炎症性CD8T细胞的水平来抑制结直肠癌细胞的增殖和PD-L1表达
Maysoon Al-Haideri
Maysoon Al-Haideri
Introduction: Silymarin as an herbal medicine has shown anticancer effects on tumor cells, while having low toxicity in normal cells. In this study, the effects of Silymarin on proliferation and apoptosis of colorectal ca...
Patients with chronic liver diseases are at risk for diabetes even before development of cirrhosis [0.03%]
慢性肝病患者在发生肝硬化之前就有糖尿病风险
Georgia Bale,Frédéric Clarembeau,Peter Stärkel et al.
Georgia Bale et al.
Background and aims: The prevalence of insulin resistance (IR) and type 2 diabetes mellitus (T2DM) is higher in patients with cirrhosis, compared to control patients without liver disease. The exact mechanism for this is ...
Nationwide trends over 10 years in epidemiology and management of pancreatic ductal adenocarcinoma: A real-world study from the French administrative database [0.03%]
法国行政数据库对胰腺导管腺癌流行病学及管理十年趋势的全国性真实世界研究
Léo Mas,Christel Castelli,Amandine Coffy et al.
Léo Mas et al.
Background & aims: Significant progress has been made in the management of pancreatic ductal adenocarcinoma (PDAC) in recent years. In this population-based study, we aimed to compare incidence, therapeutic strategies, an...
A laterally spreading tumor surrounding a barely visible appendiceal orifice [0.03%]
围绕几乎看不见的阑尾开口的侧向扩散肿瘤
Flore de Castelbajac,Salome Ouazana,Xavier Dray
Flore de Castelbajac
Siwei Tan
Siwei Tan
Portal hypertensive gastropathy (PHG) is a serious complication and the most common gastric mucosal injury amongst patients afflicted with cirrhotic or non-cirrhotic portal hypertension (PHT). The pathogenesis of PHG is not completely under...
Remifentanil represses oxidative stress to relieve hepatic ischemia/reperfusion injury via regulating BACH1/PRDX1 axis [0.03%]
瑞芬太尼通过调节BACH1/PRDX1轴抑制氧化应激以缓解肝脏缺血再灌注损伤
Yujuan You,Shoulin Chen,Huanling Deng et al.
Yujuan You et al.
Background: Hepatic ischemia-reperfusion injury (HIRI) is a major cause of liver dysfunction after clinical liver surgery, which seriously affects the prognosis of patients. Remifentanil (RE) has been verified to attenuat...