Elisabeth J Shaw,Brian Haylock,David Husband et al.
Elisabeth J Shaw et al.
Background: Oligodendroglial tumors with 1p/19q loss are more likely to be chemosensitive and have longer survival than those with intact 1p/19q, but not all respond to chemotherapy, warranting investigation of the biolog...
Activating mutation (V617F) in the tyrosine kinase JAK2 is absent in locally-confined or castration-resistant prostate cancer [0.03%]
jak2的酪氨酸激酶区域未发现激活突变(V617F)与局部局限性或雄激素剥夺治疗后的前列腺癌有关
Lei Gu,Xian-Hua Zhu,Tapio Visakorpi et al.
Lei Gu et al.
Background: Transcription factor Stat5a/b is highly critical for the viability of human prostate cancer cells in vitro and for prostate tumor growth in vivo. Stat5 is constitutively active in clinical prostate cancers but...
Glioblastomas with oligodendroglial component - common origin of the different histological parts and genetic subclassification [0.03%]
具有少突胶质细胞成分的胶质母细胞瘤-不同组织学部分的共同起源和遗传亚分类
Barbara Klink,Ben Schlingelhof,Martin Klink et al.
Barbara Klink et al.
Background: Glioblastomas are the most common and most malignant brain tumors in adults. A small subgroup of glioblastomas contains areas with histological features of oligodendroglial differentiation (GBMO). Our objectiv...
Immunohistochemical expression and localization of somatostatin receptor subtypes in androgen ablated prostate cancer [0.03%]
雄激素剥夺治疗后前列腺癌组织中生长抑素受体亚型的表达及定位分布免疫组化研究
Roberta Mazzucchelli,Doriana Morichetti,Alfredo Santinelli et al.
Roberta Mazzucchelli et al.
Objective: The aim was to examine the expression and localization of the five somatostatin receptors (termed SSTR1-5) in radical prostatectomies (RPs) from patients with prostatic adenocarcinoma (PCa) under complete andro...
p21/waf1 and smooth-muscle actin α expression in stromal fibroblasts of oral cancers [0.03%]
口腔癌基质成纤维细胞中P21/WAF1和平滑肌型肌动蛋白α的表达
Ioulia Chatzistamou,Nikolina Dioufa,George Trimis et al.
Ioulia Chatzistamou et al.
Background: Concerted alterations between stromal fibroblasts and neoplastic cells underline the carcinogenic process. Activation of alpha-smooth muscle actin (SMA) expression, a cytoskeleton protein normally expressed on...
p21/waf1 and smooth-muscle actin α expression in stromal fibroblasts of oral cancers [0.03%]
口腔癌间质成纤维细胞中P21/WAF1和平滑肌型肌动蛋白α的表达
Ioulia Chatzistamou,Nikolina Dioufa,George Trimis et al.
Ioulia Chatzistamou et al.
Background: Concerted alterations between stromal fibroblasts and neoplastic cells underline the carcinogenic process. Activation of alpha-smooth muscle actin (SMA) expression, a cytoskeleton protein normally expressed on...
ESR1 amplification is rare in breast cancer and is associated with high grade and high proliferation: a multiplex ligation-dependent probe amplification study [0.03%]
乳腺癌中ESR1扩增罕见并与高分级和高度增殖相关：基于多重连接依赖性探针扩增技术的研究
Cathy B Moelans,Hanneke N Monsuur,Johannes H de Pinth et al.
Cathy B Moelans et al.
Background: Expression of estrogen receptor alpha (ERα) is predictive for endocrine therapy response and an important prognostic factor in breast cancer. Overexpression of ERα can be caused by estrogen receptor 1 (ESR1)...
ESR1 amplification is rare in breast cancer and is associated with high grade and high proliferation: a multiplex ligation-dependent probe amplification study [0.03%]
乳腺癌中ESR1扩增罕见并伴高分级及高增值：多重连接依赖性探针扩增研究结果
Cathy B Moelans,Hanneke N Monsuur,Johannes H de Pinth et al.
Cathy B Moelans et al.
Background: Expression of estrogen receptor alpha (ERα) is predictive for endocrine therapy response and an important prognostic factor in breast cancer. Overexpression of ERα can be caused by estrogen receptor 1 (ESR1)...
TS gene polymorphisms are not good markers of response to 5-FU therapy in stage III colon cancer patients [0.03%]
TS基因多态性不能作为III期结肠癌患者5-FU治疗反应的标志物
A Fariña-Sarasqueta,M J E M Gosens,E Moerland et al.
A Fariña-Sarasqueta et al.
Aim: Although the predictive and prognostic value of thymidylate synthase (TS) expression and gene polymorphism in colon cancer has been widely studied, the results are inconclusive probably because of methodological diff...