Diagnostic Accuracy of Serum P16ink4A and FOX-P3 Concentrations for Detection of Cervical Lesions Among Women Attending a Cervical Cancer Clinic in Western Uganda: A Case-Control Study [0.03%]
乌干达西部子宫颈癌门诊部子宫颈病变患者血清P16ink4a和FOX-P3浓度检测准确性:一项病例对照研究
Frank Ssedyabane,Nixon Niyonzima,Joseph Ngonzi et al.
Frank Ssedyabane et al.
Introduction: Expression of P16ink4A and FOXP3 is correlated with the grades of cervical lesions. In this study, we determined the diagnostic accuracy of serum P16ink4A and FOXP3 concentrations for detection of cervical intraepithelial neop...
Gallic Acid Inhibits the Proliferation and Migration of Ovarian Cancer Cells via Inhibition of the PI3K-AKT Pathway and Promoting M1-Like Macrophage Polarization [0.03%]
没食子酸通过抑制PI3K-AKT途径和促进M1型巨噬细胞极化来抑制卵巢癌细胞增殖和迁移
Ran Meng,Zhengmao Zhang
Ran Meng
Ovarian cancer is one of the leading malignant women tumors that causes higher mortality, and immunotherapy has shown high potential in the treatment of advanced ovarian cancer patients by activating and mobilizing the human immune system, ...
Metformin Enhances the Chemosensitivity of Gastric Cancer to Cisplatin by Downregulating Nrf2 Level [0.03%]
二甲双胍通过下调Nrf2水平增强胃癌细胞顺铂化疗敏感性
Guihua Duan,Min Qi,Linting Xun et al.
Guihua Duan et al.
Cisplatin-based chemotherapy resistance is a common issue for cancer clinical efficacy. Metformin is being studied for its possible anticancer effect. The present study aimed to investigate whether metformin affects the chemosensitivity of ...
Omp34-Mediated Acinetobacter baumannii Invasion of Human Cervical Carcinoma Epithelial, HeLa Cells, and the Influence of Anti-Omp34 Antibodies [0.03%]
Omp34介导的阿氏不动杆菌对人宫颈癌上皮细胞(HeLa细胞)的侵袭及抗Omp34抗体的影响
Seyedeh Faezeh Hosseini,Mohammadreza Jalali Nadoushan,Zahra Fekrirad et al.
Seyedeh Faezeh Hosseini et al.
Acinetobacter baumannii is known for its ability to invade and persist within eukaryotic cells, impacting infection outcomes and disease progression. This study investigates the role of Omp34, a key outer membrane protein (Omp), in A. bauma...
An Interplay Between Pericytes, Mesenchymal Stem Cells, and Immune Cells in the Process of Tissue Regeneration [0.03%]
周细胞、间充质干细胞及免疫细胞在组织再生过程中的相互作用
Vladislav Volarevic,Carl Randall Harrell,Aleksandar Arsenijevic et al.
Vladislav Volarevic et al.
Immediately after injury, damaged cells elicit tissue regeneration, a healing process that enables optimal renewal and regrowth of injured tissues. Results obtained in a large number of experimental studies suggested that the cross talk bet...
Comparison and Analysis of the Drug-Resistance Mechanism of Osimertinib- and Almonertinib-Resistant Cell Lines [0.03%]
奥希替尼和阿美替尼耐药细胞系的药物抵抗机制比较与分析
Chuangjie Zheng,Yingfang Ren,Ke Wang et al.
Chuangjie Zheng et al.
Background: Non-small-cell lung cancer remains the leading cause of cancer-related deaths globally, and epidermal growth factor receptor mutations have been identified as crucial drivers of the disease. Encouragingly, epidermal growth facto...
Comprehensive Analysis of Potential Common Pathogenic Mechanisms for COVID-19 Infection and Gastric Cancer [0.03%]
新型冠状病毒感染与胃癌潜在的共通发病机制全面分析
Guiqian Zhang,Ning Wang,Shixun Ma et al.
Guiqian Zhang et al.
A growing body of data suggests that the prevalence of COVID-19 pneumonia in patients with stomach cancer is much higher than in the general population. However, these mechanisms are still not fully understood. After a thorough examination ...
Recombinant Human Endostatin Suppressed the Biological Behavior of Human Umbilical Vein Endothelial Cells Under Hypoxic and Hypoxic/Starvation Conditions In Vitro [0.03%]
重组人端粒酶抑制人脐静脉内皮细胞在体外缺血及缺血乏氧条件下的生物学行为
Yongsheng Jia,Cuicui Zhang,Jimin Zhao et al.
Yongsheng Jia et al.
Recombinant human endostatin (rh-endostatin) has been shown to act as an inhibitor of angiogenesis. Previous studies have indicated that rh-endostatin combined with chemotherapy can improve the objective response rate (ORR), time to progres...
Peroxiredoxin 1 Promotes Proinflammatory Cytokine Secretion in Human Dysplastic Oral Keratinocytes and Mouse Tongue Precancerous Tissues [0.03%]
过氧化氢酶1促进人类口腔黏膜不典型增生的角质形成细胞和小鼠舌癌前组织分泌促炎性细胞因子
Min Zhang,Wenjing Li,Jing Li et al.
Min Zhang et al.
Oxidative stress, a widespread phenomenon involved in many pathological conditions, may be closely related with the progression of oral leukoplakia (OLK). Under chronic inflammation, oxidative stress could stimulate the local formation of a...
Chemopreventive Potential of Paddy Waste: A Promising Approach Against Benign Prostate Hyperplasia in Spontaneously Hypertensive Rats [0.03%]
稻杆废物的化学预防潜力:对自发性高血压大鼠良性前列腺增生的一种有前景的方法
Azman Seeni,Atif Amin Baig,Mogana Das Murtey
Azman Seeni
Background: Benign prostate hyperplasia (BPH) is common in elderly men. Previously, paddy waste (both husk and straw) reportedly had chemopreventive potential. The main aim of this study was to explore the chemopreventive properties of padd...